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Papers
20 resultsShowing papers similar to Impact of MDRs on COVID-19 Patients Among Developing Countries
ClearCOVID-19 pandemic and antimicrobial resistance in developing countries
This review examined how the COVID-19 pandemic increased antimicrobial drug use and resistance in developing countries, highlighting that improper waste disposal, hospital effluents, and microplastics acting as vectors for antibiotic-resistant organisms compound resistance risks in lower-income settings that already lack diagnostic capacity and infection control infrastructure.
The Role of COVID-19 on Antibiotics Resistance: a Review-based Study
This review examines the role of COVID-19 in accelerating antibiotic resistance, discussing how overuse of antibiotics during the pandemic increased selective pressure on bacteria. The authors review mechanisms by which SARS-CoV-2 infection leads to secondary bacterial infections requiring antibiotic treatment. Antibiotic resistance is environmentally relevant because resistant genes are often co-located with microplastics in aquatic environments.
COVID-19 and antimicrobial resistance: A cross-study
This review explores how the COVID-19 pandemic accelerated antimicrobial resistance through increased antibiotic use, widespread disinfectant application, and massive volumes of plastic personal protective equipment waste. Researchers found that pandemic-related microplastic pollution creates additional surfaces for resistant bacteria to colonize and exchange resistance genes. The study highlights the intersection of pandemic waste management and the global antibiotic resistance crisis.
Antidrug resistance in the Indian ambient waters of Ahmedabad during the COVID-19 pandemic
Researchers compared antibiotic resistance patterns in Escherichia coli isolated from ambient water in Ahmedabad, India before and during the COVID-19 pandemic, finding increased multi-drug resistance during the pandemic period, likely linked to elevated antibiotic consumption.
Antibiotic Resistance Pattern in Intensive Care Unit Patients of Bangladesh
This observational study examined antibiotic resistance patterns in intensive care unit patients at a hospital in Bangladesh, characterizing the organisms and resistance profiles of infections in critically ill patients. The study found high rates of multi-drug resistance among ICU pathogens, with implications for empirical treatment protocols in resource-limited settings.
Combating antimicrobial resistance: the silent war
This review examines the growing global crisis of antimicrobial resistance, where bacteria become immune to antibiotics due to overuse in medicine and agriculture. Although focused on drug resistance, the paper is relevant to microplastic research because microplastics have been shown to harbor antibiotic-resistant bacteria and facilitate the transfer of resistance genes in the environment, potentially making this public health crisis worse.
A systematic review of sources, occurrence, behavior and risks of global marine antibiotics
This systematic review of global marine antibiotic contamination found that sulfamethoxazole is the most frequently detected antibiotic in seawater, sediment, and marine organisms, with the highest concentrations along coastal China. Coexisting contaminants like microplastics may enhance antibiotic impacts and drive antibiotic resistance gene development in marine environments.
Trends in and Future Research Direction of Antimicrobial Resistance in Global Aquaculture Systems: A Review
This review analyzed trends in antimicrobial resistance in global aquaculture systems, finding that antibiotic overuse has accelerated the development of resistance genes and identifying key research directions for addressing this growing public health concern.
Antimicrobial Resistance Development Pathways in Surface Waters and Public Health Implications
Researchers evaluated the pathways through which antibiotic-resistant bacteria develop and spread in surface waters, identifying healthcare facilities, wastewater, agricultural runoff, and wildlife as major vehicles. The study found that antibiotic residues, heavy metals, and even climate change drive the emergence of resistance in aquatic environments. The findings highlight that surface water contamination poses a growing public health threat, particularly for food and animal handlers who face higher exposure risk.
Multidrug-resistant Pseudomonas aeruginosa in ICU patients and hospital surfaces: β-lactamase burden, biofilm formation and clonal spread
Researchers characterized 216 Pseudomonas aeruginosa isolates from ICU patients and hospital surfaces in Brazil, finding that 30.5% were multidrug-resistant, 77.3% formed strong biofilms, and clonal analysis revealed cross-hospital transmission — highlighting the role of hospital environments in spreading antibiotic-resistant pathogens.
Prevalence of pharmaceuticals and personal care products, microplastics and co-infecting microbes in the post-COVID-19 era and its implications on antimicrobial resistance and potential endocrine disruptive effects
This review examines how the COVID-19 pandemic increased environmental contamination from pharmaceuticals, personal care products, and microplastics, all of which can promote antibiotic resistance and disrupt hormones. The surge in mask use, sanitizer disposal, and medication contributed to higher levels of these pollutants in waterways. The combination of microplastics with pharmaceutical residues creates a compounding threat where plastics can carry drug-resistant bacteria and hormone-disrupting chemicals into water supplies.
Interplay Between Antimicrobial Resistance and Global Environmental Change
This review explores how global environmental changes, including pollution, climate change, and habitat destruction, are accelerating the spread of antimicrobial resistance. Researchers found that factors like microplastic pollution, heavy metals, and pharmaceutical waste create conditions that promote the evolution of resistant bacteria. The study suggests that addressing antimicrobial resistance requires considering it as an environmental problem, not just a medical one.
Impact of Pharmaceutical Waste Generation and Handling on Environmental Health in Developing Countries: COVID – 19 Pandemic in Perspective!
This paper examines how pharmaceutical waste generation and handling during the COVID-19 pandemic exacerbated environmental health risks in developing countries, where inadequate waste management infrastructure led to increased contamination of soil and water.
The role of emerging organic contaminants in the development of antimicrobial resistance
Researchers reviewed how emerging organic contaminants — including plastics, pharmaceuticals, and biocides found throughout the environment — can promote the development and spread of antibiotic resistance in microbes. The study argues that tackling antimicrobial resistance requires addressing not just antibiotic overuse but also the broader chemical pollution that shapes microbial communities.
Antibiotic Resistance: Moving From Individual Health Norms to Social Norms in One Health and Global Health
This review argues that antibiotic resistance should be understood as a global pandemic requiring coordinated One Health and Global Health approaches, rather than just an individual patient concern. Researchers explain how resistant bacteria and resistance genes spread across humans, animals, food systems, water, and natural environments including those contaminated with microplastics. The study advocates for social norms and socioeconomic frameworks that address antibiotic resistance within the broader context of environmental sustainability.
Review on designing a comprehensive macroeconomic modeling strategy for antimicrobial resistance
This review examines the macroeconomic dimensions of antimicrobial resistance (AMR), which caused 1.27 million deaths in 2019, proposing three conceptual frameworks that integrate drivers including climate variability, demographic trends, and plastic pollution to model the economy-wide consequences of AMR spread.
Occurrence, Bioaccumulation, Metabolism and Ecotoxicity of Fluoroquinolones in the Aquatic Environment: A Review
This review examines fluoroquinolone antibiotic contamination in waterways across 32 countries, finding widespread pollution especially in developing nations. These antibiotics accumulate in aquatic organisms and move through the food chain, with toxicity varying by species and environmental conditions. The co-occurrence of antibiotics and microplastics in water is a growing concern, as microplastics can absorb and transport these drugs, potentially increasing human exposure.
Evolution and Emergence of Antibiotic Resistance in Given Ecosystems: Possible Strategies for Addressing the Challenge of Antibiotic Resistance
This review traces the history of antibiotic resistance and examines how it evolves and spreads across aquatic and terrestrial ecosystems. Researchers discuss the ecological roles of antibiotics and the modern tools used to identify resistant organisms in various environments. The study highlights the ecotoxicological impact of antibiotic-resistant bacteria and explores potential strategies, including environmental monitoring, to address this growing public health challenge.
Antibiotic and Non-Antibiotic Determinants of Antimicrobial Resistance: Insights from Water Ecosystems
This review explains how non-antibiotic pollutants like heavy metals, biocides, and microplastics are contributing to antibiotic resistance in water systems, beyond the well-known problem of antibiotic overuse. Wastewater treatment plants are hotspots where these pollutants interact with bacteria, promoting the spread of resistance genes through mobile genetic elements. The findings are concerning for human health because drug-resistant bacteria from water environments can ultimately reach people through drinking water and food.
Microplastic-associated antimicrobial resistance: an AI-aided systematic literature review and distribution mapping
An AI-aided systematic literature review and distributional analysis examined microplastic-associated antimicrobial resistance (AMR) in aquatic and other environments. The authors found growing evidence that microplastics accelerate AMR spread, with important implications for environmental and health policy.