Papers

61,005 results
|
Article Tier 2

Nanoplastics and their combined effects with sulphamethoxazole on the free-floating aquatic plant Lemna major

Researchers studied the combined effects of polystyrene nanoplastics and the antibiotic sulfamethoxazole on free-floating freshwater organisms, examining how co-exposure to these two pollutants interacts compared to individual exposures. Nanoplastics altered the bioavailability and toxicity of the antibiotic, demonstrating complex mixture effects in aquatic systems.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Toxic effects and mechanisms of nanoplastics and sulfonamide antibiotics on Scenedesmus obliquus

This study tested the combined toxic effects of nanoplastics and sulfonamide antibiotics on freshwater algae, finding that the pollutants together were more harmful than either one alone. The mixture reduced algae growth, damaged cell membranes, and increased oxidative stress. Since algae form the base of aquatic food chains, this damage could cascade through ecosystems and eventually affect the quality of water and food that humans depend on.

2025 Ecotoxicology and Environmental Safety 6 citations
Article Tier 2

Interactive toxicity effects of metronidazole, diclofenac, ibuprofen, and differently functionalized nanoplastics on marine algae Chlorella sp.

Researchers examined the combined toxicity of common pharmaceutical drugs and nanoplastics with different surface coatings on marine algae. They found that the interaction between drugs and nanoplastics produced effects ranging from additive to synergistic, depending on the specific combination, with amine-coated nanoplastics generally causing more harm. The study highlights that real-world mixtures of pharmaceutical and plastic pollutants in oceans may pose greater risks to marine life than either contaminant alone.

2025 Environmental Science Processes & Impacts 3 citations
Article Tier 2

Toxicity interaction of polystyrene nanoplastics with sulfamethoxazole on the microalgae Chlamydomonas reinhardtii: A closer look at effect of light availability

Researchers studied how light availability influences the combined toxicity of polystyrene nanoplastics and the antibiotic sulfamethoxazole on the microalga Chlamydomonas reinhardtii. The study found that the interaction between these two pollutants was largely antagonistic under low and normal light conditions, as nanoplastics could adsorb the antibiotic and reduce its bioavailability, highlighting the importance of environmental factors in determining combined pollutant toxicity.

2023 Journal of Environmental Management 17 citations
Article Tier 2

Combined effects of polyethylene microplastics and nanoparticles on Lemna minor

Researchers adsorbed ZnO and TiO2 nanoparticles onto polyethylene microplastics extracted from cosmetics and tested their combined toxicity on the aquatic plant Lemna minor, finding that while specific growth rate and chlorophyll a content were unaffected, both nanoparticle-coated microplastic combinations inhibited root growth and reduced chlorophyll b content.

2022 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Toxicological Effects of Microplastics and Sulfadiazine on the Microalgae Chlamydomonas reinhardtii

Researchers examined the combined toxicity of polystyrene microplastics and the antibiotic sulfadiazine on the freshwater microalga Chlamydomonas reinhardtii. The results suggest that both substances individually and in combination inhibited algal growth, and the interaction between microplastics and antibiotics may alter their respective toxic effects on aquatic organisms.

2022 Frontiers in Microbiology 40 citations
Article Tier 2

The combined toxicity effect of nanoplastics and glyphosate on Microcystis aeruginosa growth

Researchers found that cationic nanoplastics adsorb glyphosate so strongly that co-exposure actually reduces the herbicide's toxicity to algae by sequestering it — but the nanoplastics coated in glyphosate adhere more readily to algal surfaces, potentially concentrating both pollutants further up the food chain.

2018 Environmental Pollution 271 citations
Article Tier 2

Combined toxic effects of enrofloxacin and microplastics on submerged plants and epiphytic biofilms in high nitrogen and phosphorus waters

Researchers studied the combined effects of the antibiotic enrofloxacin and microplastics on the submerged plant Myriophyllum verticillatum in nutrient-rich water. The study found that while microplastics alone had little effect, their combination with enrofloxacin produced synergistic toxic effects, reducing the plant's ability to absorb nitrogen and phosphorus and decreasing photosynthetic pigment content.

2022 Chemosphere 52 citations
Article Tier 2

Single and combined effects of antibiotics and nanoplastics from surgical masks and plastic bottles on pathogens

Researchers examined the combined effects of nanoplastics from surgical masks and plastic bottles with antibiotics on pathogens, finding that co-exposure created synergistic toxic effects and altered antimicrobial resistance patterns in bacteria.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 23 citations
Article Tier 2

Combined toxic effects of nanoplastics and norfloxacin on mussel: Leveraging biochemical parameters and gut microbiota

Researchers exposed mussels to nanoplastics and the antibiotic norfloxacin, both alone and together, and found that the combination caused greater biochemical stress than either pollutant alone. Nanoplastics appeared to carry the antibiotic into mussel tissues, increasing its bioavailability and impact on gut microbiota. The findings suggest that nanoplastics can amplify the toxicity of other contaminants in marine organisms.

2023 The Science of The Total Environment 30 citations
Article Tier 2

Microplastics and co-pollutant with ciprofloxacin affect interactions between free-floating macrophytes

Researchers found that polyethylene microplastics and ciprofloxacin co-pollutants altered competitive interactions between free-floating macrophytes, with combined exposure affecting plant growth and physiological responses differently than individual pollutant exposure.

2022 Environmental Pollution 39 citations
Article Tier 2

Single and combined effects of polystyrene nanoplastics and Cd on submerged plants Ceratophyllum demersum L.

Researchers studied the combined effects of nanoplastics and cadmium, a toxic heavy metal, on the aquatic plant Ceratophyllum demersum. They found that nanoplastics worsened cadmium's harmful effects on plant growth, photosynthesis, and cellular health, reducing growth rates by over 35%. The study suggests that when nanoplastics and heavy metals co-occur in water, their combined impact on aquatic plants may be more severe than either pollutant alone.

2023 The Science of The Total Environment 51 citations
Article Tier 2

Interactive effects of selected pharmaceutical products (metronidazole, diclofenac, ibuprofen) and differently functionalized nanoplastics on marine algae Chlorella sp.

The combined toxicity of three pharmaceutical products (metronidazole, diclofenac, ibuprofen) and polystyrene nanoplastics with different surface functionalization (NH2 and COOH) was tested on marine algae Chlorella sp. Polystyrene nanoplastics at 1 mg/L caused substantial growth inhibition, while combining pharmaceuticals with nanoplastics reduced rather than amplified toxicity.

2024 Research Square (Research Square) 1 citations
Article Tier 2

Interactive effect of nanoplastic particles and phototoxicant on microalgae

Researchers studied the combined effects of polystyrene nanoparticles and methylene blue, a phototoxic compound, on two species of freshwater microalgae. Depending on concentrations and exposure duration, the combination produced synergistic, additive, or antagonistic toxic effects on algal growth. The study highlights that nanoplastics can modify the toxicity of other pollutants in complex and sometimes unpredictable ways.

2026 Advances in Natural Sciences Nanoscience and Nanotechnology
Article Tier 2

Integrating transcriptomics and biochemical analysis to understand the interactive mechanisms of the coexisting exposure of nanoplastics and erythromycin on Chlorella pyrenoidosa

Researchers used transcriptomics and biochemical analysis to study how nanoplastics and the antibiotic erythromycin interact when both are present in water with the green alga Chlorella pyrenoidosa. They found that the combined toxicity was dynamic, shifting from synergistic to antagonistic effects depending on nanoplastic concentration and exposure duration. The study indicates that co-exposure disrupts algal cell membranes, induces oxidative stress, and reduces photosynthetic efficiency.

2023 Chemosphere 11 citations
Article Tier 2

Co-Exposure to Glyphosate and Polyethylene Microplastic Affects Their Toxicity to Chlorella vulgaris: Implications for Algal Health and Aquatic Risk

Researchers assessed the individual and combined toxicity of polyethylene microplastics and glyphosate to the microalga Chlorella vulgaris in acute and chronic exposures. The combination caused greater toxicity than either contaminant alone, particularly at chronic exposure durations, indicating synergistic effects relevant to agricultural runoff contamination.

2025 Molecules
Article Tier 2

Combined toxicity of nanoplastics and microcystin-LR to sulfate-reducing bacteria and the underlying mechanisms

Researchers exposed freshwater aquaculture microcosms to polyethylene nanoplastics and the algal toxin microcystin-LR, finding that nanoplastics strongly adsorb the toxin and that combined exposure disrupts sulfur cycling bacteria more severely than either contaminant alone, raising ecological concerns for aquaculture water quality.

2026 Environmental Pollution
Article Tier 2

Fluorescent nanoplastics enhanced toxicity of Graphene oxide nanoparticles in freshwater algae Scenedesmus obliquus

The presence of fluorescent polystyrene nanoplastics significantly increased the toxicity of graphene oxide nanoparticles to the freshwater alga Scenedesmus obliquus, demonstrating that nanoplastics can act as vectors that amplify the effects of co-occurring nanocontaminants.

2024
Article Tier 2

Higher toxicity induced by co-exposure of polystyrene microplastics and chloramphenicol to Microcystis aeruginosa: Experimental study and molecular dynamics simulation

Researchers studied what happens when the antibiotic chloramphenicol and polystyrene microplastics are present together in water containing blue-green algae. The study found that the combined exposure was more toxic to the algae than either pollutant alone, disrupting photosynthesis and gene expression. The findings suggest that microplastics and antibiotics may interact in ways that amplify their harmful effects on aquatic ecosystems.

2023 The Science of The Total Environment 38 citations
Article Tier 2

Single and combined toxicity effects of nanoplastics and bisphenol F on submerged the macrophyte Hydrilla verticillata

Researchers investigated the combined toxicity of polystyrene nanoplastics and bisphenol F on the aquatic plant Hydrilla verticillata, finding that nanoplastics alone and in combination with BPF significantly reduced growth rates and chlorophyll content, while BPF alone had no impact.

2021 The Science of The Total Environment 45 citations
Meta Analysis Tier 1

When antibiotics encounter microplastics in aquatic environments: Interaction, combined toxicity, and risk assessments

A meta-analysis of the combined toxicity of antibiotics and microplastics in aquatic environments found significant adverse effects on algae but limited apparent effects on fish and daphnia. Microplastics alter antibiotic environmental behavior through adsorption and co-transport, and their coexistence is widespread across global aquatic study sites, though standardized risk assessment methods for combined exposure remain lacking.

2024 The Science of The Total Environment 33 citations
Article Tier 2

Effects of polystyrene nanoplastics and PCB-44 exposure on growth and physiological biochemistry of Chlorella vulgaris

Researchers studied the combined effects of polystyrene nanoplastics and a common industrial pollutant (PCB-44) on a freshwater green algae species over both short and long exposure periods. They found that both contaminants individually inhibited algae growth and disrupted cell functions, but their combined presence intensified the damage. The study highlights that when nanoplastics and chemical pollutants co-exist in water, they can create compounding harmful effects on aquatic organisms.

2024 The Science of The Total Environment 7 citations
Article Tier 2

Unraveling individual and combined toxicity of nano/microplastics and ciprofloxacin to Synechocystis sp. at the cellular and molecular levels

Researchers studied the individual and combined toxic effects of nano- and microplastics with the antibiotic ciprofloxacin on a freshwater cyanobacterium. They found that while each pollutant caused harm on its own, the antibiotic actually showed an antagonistic interaction with the plastic particles, reducing some of their combined toxicity. The study provides important insights into how microplastics and pharmaceutical pollutants interact in aquatic environments, which may complicate pollution risk assessments.

2021 Environment International 105 citations
Article Tier 2

Nanoplastics amplify ARG colonization and Alter microbial communities in the phycosphere of Chlorella pyrenoidosa under antibiotic stress

Researchers studied how nanoplastics combined with antibiotics affect the bacterial communities surrounding the green alga Chlorella pyrenoidosa and the spread of antibiotic resistance genes. They found that while nanoplastics alone had minimal effects on algal growth, the combination with antibiotics significantly increased toxicity and amplified the abundance of antibiotic resistance genes. The findings suggest that nanoplastic pollution in waterways may worsen the spread of antibiotic resistance, which has implications for both ecosystem and human health.

2025 Environmental Chemistry and Ecotoxicology 3 citations