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61,005 resultsShowing papers similar to Trends in Research on The Effects of Nutritional Supplements Against Nephrotoxicity; A Bibliometric Study
ClearThe Traditional Chinese Medicine in Treating Diabetic Nephropathy: A Bibliometric Analysis
This bibliometric analysis reviews research trends on Traditional Chinese Medicine for treating diabetic nephropathy. The study identifies key research hotspots including the clinical efficacy of herbal treatments and their pharmacological mechanisms, with improving oxidative stress and regulating gut microbiota highlighted as promising directions for future investigation.
Nutrition, cognition and chronic kidney disease: A comprehensive review of interactions and interventions.
This review examined the relationship between nutrition, cognition, and chronic kidney disease (CKD), finding that dietary deficiencies and uremic toxins in CKD patients impair cognitive performance across memory, attention, and executive functions. Exposure to environmental contaminants including plasticizers was identified as a contributing factor to cognitive decline in this population.
Attenuative Effects of Ginkgetin Against Polystyrene Microplastics-Induced Renal Toxicity in Rats
Researchers found that ginkgetin, a natural flavonoid, significantly reduced polystyrene microplastic-induced kidney damage in rats by restoring antioxidant enzyme activity and reducing oxidative stress and inflammation markers.
Wcn23-0028 Dietary Sodium and Potassium Intakes and Prevalent Kidney Stone: the National Health and Nutritional Examination Survey 2011-2018
Researchers examined associations between dietary sodium and potassium intakes and the prevalence of kidney stones using national survey data from 2011–2018, finding that dietary mineral ratios may influence kidney stone risk. The study contributes to understanding how diet composition relates to urinary tract health.
Nanoparticles Enhance Plant Resistance to Abiotic Stresses: A Bibliometric Statistic
This bibliometric analysis of nanoparticle research in plant abiotic stress tolerance mapped publication trends, key countries, institutions, and research themes, finding rapid growth in the field and identifying drought, salinity, and heavy metal stress as the most studied applications of nanoparticles for improving crop resilience.
Mapping research frontiers in microplastics-induced oxidative stress: a bibliometric analysis (2010–2024)
This bibliometric analysis mapped research trends in microplastic-induced oxidative stress across nearly 2,000 studies published between 2010 and 2024. Researchers identified key themes including gut health impacts, nanoplastic toxicity, and the role of specific cellular stress pathways as the most active research frontiers. The study provides a roadmap of where the science is headed and suggests that antioxidant-based interventions may be a promising area for future work.
Emerging tropane alkaloids: Global development and potential health threats
This bibliometric study maps the research landscape of tropane alkaloids, a class of plant-derived compounds with both pharmaceutical and toxic properties, by analyzing over 1,200 publications from 1953 to 2022. The study identifies an emerging trend since 2018 toward monitoring tropane alkaloid contamination in food products, suggesting growing concern about their potential health implications in the food supply.
Environmental Nephrotoxicity Across the Life Course: Oxidative Stress Mechanisms and Opportunities for Early Intervention
This review examines how environmental pollutants, including microplastics, nanoplastics, bisphenol A, and phthalates, can damage kidneys across a person's lifetime, with early-life exposure being particularly concerning. Researchers found that these pollutants promote oxidative stress, inflammation, and epigenetic changes that can program lifelong susceptibility to kidney problems. The study highlights antioxidant-based interventions as a potential strategy for protecting kidney health from environmental contaminant exposure.
Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of Bushen Huashi decoction against kidney stones
This study used network pharmacology and laboratory validation to reveal that a traditional Chinese herbal formula (Bushen Huashi decoction) combats kidney stones by modulating estrogen receptor, NRF2/HO-1 antioxidant, and apoptosis signaling pathways.
Global trends and hotspots of gastrointestinal microbiome and toxicity based on bibliometrics
This bibliometric analysis mapped global research trends and hotspots in gastrointestinal microbiome and toxicity studies, finding that modifications to the gut microbiome could offer new directions for treating and mitigating toxic exposures.
Ameliorative Effects of Rhamnetin against Polystyrene Microplastics-Induced Nephrotoxicity in Rats
Researchers investigated whether the flavonoid rhamnetin could protect against kidney damage caused by polystyrene microplastics in rats. The study found that microplastic exposure significantly increased oxidative stress and inflammatory markers while reducing antioxidant enzyme activity, but co-treatment with rhamnetin restored kidney parameters and mitigated the damage.
The threat of microplastics to human kidney health: Mechanisms of nephrotoxicity and future research directions
This review examines the growing evidence that microplastics can reach and damage human kidneys, where they were first detected in 2023. Short-term exposure triggers oxidative stress and inflammation, while long-term exposure may lead to kidney scarring through a process called ferroptosis, a type of cell death linked to iron buildup. The authors propose that microplastics may also activate the immune system in kidneys through a gut-kidney connection, highlighting that kidney health is an important but overlooked concern in microplastic research.
Microplastic exposure and its consequences for renal and urinary health: systematic review of in vivo studies
This systematic review examines animal studies on how microplastic exposure affects the kidneys and urinary system. The evidence suggests that microplastics can accumulate in kidney tissue and may cause inflammation and oxidative stress, raising concerns about potential long-term effects on human kidney health as our exposure to these particles continues to grow.
Protective Effect of Resveratrol on Kidney Disease and Hypertension Against Microplastics Exposure in Male Juvenile Rats
Researchers investigated whether resveratrol, a natural plant compound, could protect young rats from kidney damage and high blood pressure caused by microplastic exposure. They found that microplastics elevated blood pressure and creatinine levels through oxidative stress, and that resveratrol treatment effectively prevented these effects. The study suggests resveratrol may offer protective benefits against organ damage linked to microplastic exposure, partly by improving gut microbiota balance.
Microplastics and CKD: Are we overlooking the role of ecotoxins
This review argues that microplastics deserve greater consideration as a contributing factor to chronic kidney disease, synthesizing evidence that MPs can accumulate in renal tissue, trigger inflammation and oxidative stress, and may represent an underappreciated environmental driver of CKD.
Micro/nano plastics in the urinary system: Pathways, mechanisms, and health risks.
This review synthesizes emerging evidence on how micro- and nano-plastics reach the urinary system, accumulate in kidney and bladder tissue, and cause damage through oxidative stress, inflammation, and disruption of cellular function. The authors conclude that the urinary system is a primary site of microplastic accumulation and call for more research on long-term health impacts.
Evaluation of Possible Ameliorative Role of Robinetin to Counteract Polystyrene Microplastics Instigated Renal Toxicity in Rats
Researchers tested whether robinetin, a plant-derived compound, could protect rat kidneys from damage caused by polystyrene microplastic exposure. They found that microplastics caused significant kidney harm through oxidative stress, inflammation, and cell death, but robinetin supplementation substantially reversed these effects. The study suggests that natural antioxidant compounds may offer a protective strategy against microplastic-related organ damage.
Nexus Between Sarcopenia and Microbiome Research: A Bibliometric Exploration
Researchers conducted a bibliometric analysis of the intersection between sarcopenia and microbiome research, analyzing 997 articles from the Science Citation Index Extended Database to map scientific production, international collaboration networks, and emerging research hotspots in this growing field.
Protective Effect of Astragaloside IV against Cadmium-Induced Damage on Mouse Renal Podocytes (MPC5)
This paper is not about microplastics; it investigates how the plant compound Astragaloside IV protects kidney cells from cadmium-induced damage, examining mitochondrial and autophagy pathways.
Galangin attenuates oxidative stress-mediated apoptosis in high glucose-induced renal tubular epithelial cells through modulating renin–angiotensin system and PI3K/AKT/mTOR pathway
Researchers found that a plant compound called galangin protected kidney cells from damage caused by high blood sugar by reducing oxidative stress and activating protective signaling pathways. While focused on diabetes treatment, this research is not directly related to microplastic contamination.
Gut Microbiota Interventions to Retain Residual Kidney Function
This review examines strategies to modify gut bacteria in patients with chronic kidney disease in order to slow further kidney damage. Researchers found that gut imbalances in these patients lead to increased production of harmful substances that can worsen kidney function. The study suggests that dietary interventions, probiotics, and other approaches to restore healthy gut microbiota may help preserve remaining kidney function and improve patient outcomes.
Progress of Ecological Restoration Research Based on Bibliometric Analysis
This bibliometric analysis of over 23,000 publications from 1990 to 2022 mapped global ecological restoration research trends, identified key hotspots around topics like soil and vegetation recovery, and projected future directions for the field.
Bibliometric and visual analysis of heavy metal health risk assessment: development, hotspots and trends
Researchers conducted a bibliometric analysis of heavy metal health risk assessment literature from 2000 to 2022, identifying development trends and research hotspots. The study reveals growing global attention to environmental heavy metal contamination, which often co-occurs with microplastic pollution in soil and water systems.
Polyethylene microplastics disrupt renal function, mitochondrial bioenergetics, redox homeostasis, and histoarchitecture in Wistar rats
Researchers gave rats polyethylene microplastics orally for 28 days and found dose-dependent kidney damage, including impaired filtration, electrolyte imbalances, and tissue inflammation. The microplastics depleted antioxidant defenses, increased oxidative stress markers, and disrupted mitochondrial energy production in kidney cells, identifying the kidneys as a critical target of microplastic toxicity.