Papers

61,005 results
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Article Tier 2

Micro(nano)plásticos en el medio ambiente: una descripción de los efectos potenciales a la salud humana

This Spanish-language review summarizes in vitro and in vivo evidence on how micro- and nanoplastics (1 µm–5 mm and below 1 µm) accumulate in the human body and trigger adverse biological responses. It emphasizes the growing public health concern as plastic fragmentation accelerates and human internal exposure becomes increasingly documented.

2023 EPISTEMUS
Article Tier 2

Effects of Nanoplastics on Human Health: A Comprehensive Study

This comprehensive review examines the diverse health effects of nanoplastics, drawing on toxicology, environmental science, and epidemiology to document how these particles interact with human biological systems. The authors conclude that nanoplastics represent a growing public health concern requiring further investigation.

2024 International Journal of Innovative Science and Research Technology (IJISRT) 1 citations
Systematic Review Tier 1

Toxicity and Accumulation of Nanoplastics Materials: A Review of Experimental Evidence Across Biological Systems

This systematic review of studies from 2010 to 2025 found that nanoplastics can penetrate biological barriers and accumulate in tissues across many organisms. Their tiny size makes them especially concerning because they can enter cells, cause oxidative stress and inflammation, and potentially affect organ function in ways that larger plastic particles cannot.

2025 Biomedical & Pharmacology Journal
Review Tier 2

Micro- and nanoplastics: origin, sources of intake and impact on human health (literature review)

This literature review synthesizes mechanisms by which micro- and nanoplastics interact with living organisms, examining their physicochemical properties, routes of human exposure, and documented health effects across multiple organ systems.

2025 Hygiene and Sanitation
Meta Analysis Tier 1

Systemic Accumulation and Distribution of Micro- and Nanoplastics in Human Tissues and Their Impact on Health: A Systematic Review

This systematic review synthesizes human evidence on the presence of micro- and nanoplastics in body tissues and fluids, including blood, lungs, placenta, breast milk, and liver. The research confirms that plastic particles can cross biological barriers and accumulate in multiple organ systems. While the long-term health effects are still being studied, the widespread presence of plastics inside the human body raises significant health concerns.

2026 Open Science Framework
Article Tier 2

Implicaciones de la exposición a microplásticos en salud humana. Revisión bibliográfica

This Spanish-language review summarizes health implications of microplastic exposure, covering how microplastics enter the human body through food, water, and air, and what biological effects have been observed. The review notes that virtually all products in modern life contain some form of plastic.

2019
Article Tier 2

Micro and nano-plastics, a threat to human health?

This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.

2022 PubMed 38 citations
Systematic Review Tier 1

A systematic review of the impacts of exposure to micro- and nano-plastics on human tissue accumulation and health

This systematic review found growing evidence that micro- and nanoplastics accumulate in human tissues including lungs, gut, and blood, with lab studies showing potential disruption to immune, reproductive, endocrine, and nervous systems. The review identifies ingestion, inhalation, and dermal contact as the three main exposure routes and highlights that the smallest nanoplastic particles pose the greatest concern due to their ability to cross biological barriers.

2023 Eco-Environment & Health 180 citations
Article Tier 2

Recent advances in toxicological research and potential health impact of microplastics and nanoplastics in vivo

This review summarizes the growing body of research on how micro- and nanoplastics affect living organisms, covering impacts from physical tissue damage and gut disruption to reproductive harm and immune system interference. Researchers found that these tiny particles can also act as carriers for heavy metals, toxic chemicals, and pathogens, potentially amplifying their harmful effects. The evidence indicates that microplastics may move up the food chain and ultimately reach humans, though the full extent of health risks remains under investigation.

2022 Environmental Science and Pollution Research 117 citations
Article Tier 2

Microplastics in Human Tissues: Sources, Distribution, Toxicological Effects, and Health Implications

Researchers reviewed the growing body of evidence that microplastics accumulate in human tissues — including lung, blood, placenta, breast milk, and heart tissue — where they can trigger inflammation, oxidative stress, and cell death. The review highlights urgent knowledge gaps around how plastic particles move through the body and what their long-term health effects may be.

2025 International Research Journal of Modernization in Engineering Technology and Science
Article Tier 2

Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health

This review examines the growing evidence that micro- and nanoplastics can enter the human body through food, water, and air, and may contribute to harmful biological effects. Researchers found that these tiny particles can trigger oxidative stress, inflammation, and disruption of hormonal and immune systems in laboratory studies. The study highlights the need for a unified research approach to better understand how microplastic exposure may affect long-term human health.

2024 Nano LIFE 5 citations
Article Tier 2

Human exposure to micro- and nanoplastic: biological effects and health consequence

This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.

2023 Reviews in Biological and Biomedical Sciences 3 citations
Article Tier 2

[Human Accumulation and Toxic Effects of Microplastics:A Critical Review].

This review summarizes how microplastics enter the human body through food, drinking water, and air, and where they tend to accumulate in organs and tissues. Researchers found evidence that microplastics can trigger inflammatory responses and oxidative stress in the body. The study calls for more research into the long-term health effects of continuous microplastic exposure in humans.

2024 PubMed 5 citations
Article Tier 2

Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances

This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.

2025 Microplastics 3 citations
Article Tier 2

Micro(nano)plastics, an emerging health problem

This review frames micro- and nanoplastics as an emerging human health problem, synthesizing evidence of exposure routes, organ-level accumulation, and biological effects, and calling for updated regulatory frameworks to address this novel class of environmental contaminants.

2025 Environmental Research and Ecotoxicity
Systematic Review Tier 1

A Systematic Review of the Toxicokinetics of Micro- and Nanoplastics in Mammals Following Digestive Exposure

This systematic review summarizes existing research on what happens to micro and nanoplastics after mammals ingest them through food and water. The evidence shows these particles can survive digestion and potentially cross into tissues and organs, raising important questions about long-term health effects from the microplastics we unknowingly consume every day.

2025 Applied Sciences 6 citations
Review Tier 2

A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health

This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.

2022 Marine Pollution Bulletin 379 citations
Article Tier 2

Micro-and Nanoplastic-Induced Biochemical Toxicity: Emerging Mechanisms and Health Risks Across Biological Systems

This comprehensive review synthesizes current understanding of how micro- and nanoplastics cause biochemical toxicity across biological systems, from plants and invertebrates to vertebrates and humans. Key mechanisms include oxidative stress, membrane disruption, immune activation, genotoxicity, endocrine disruption, and microbiome perturbation, all modulated by particle size, shape, and surface chemistry. The authors highlight critical gaps in standardization, chronic low-dose effect data, and the need for translatable biomarkers for risk assessment.

2026 IDOSR JOURNAL OF BIOCHEMISTRY BIOTECHNOLOGY AND ALLIED FIELDS
Systematic Review Tier 1

Unveiling the presence of micro and nanoplastics in human biological matrices: A systematic review covering the latest five years from 2020 to 2025

This systematic review covering 2020-2025 confirmed the presence of micro- and nanoplastics in human blood, placenta, lungs, liver, kidneys, and other biological matrices. The findings demonstrate that plastic particles are accumulating in human tissues through ingestion, inhalation, and dermal contact, raising urgent questions about long-term health consequences.

2025 The Science of The Total Environment 1 citations
Review Tier 2

Microplastics and Human Health: A Comprehensive Review on Exposure Pathways, Toxicity, and Emerging Risks

This comprehensive review examines microplastic exposure pathways in humans, methods of detection, and the potential toxic effects on various biological systems. The study highlights growing evidence that microplastics can enter the body through ingestion, inhalation, and dermal contact, and may affect multiple organ systems, though significant uncertainties remain about long-term health outcomes.

2026 Microplastics
Article Tier 2

Eco-toxicity of nano-plastics and its implication on human metabolism: Current and future perspective

This review examines the sources, bioaccumulation pathways, and potential health effects of nanoplastics on human metabolism. Researchers found that nanoplastics can enter the body primarily through ingestion of contaminated food and packaging, and evidence suggests they may interfere with metabolic pathways and contribute to organ dysfunction. The study highlights that significant knowledge gaps remain in assessing the human health risks of nanoplastic exposure.

2022 The Science of The Total Environment 61 citations
Article Tier 2

Micro(Nano)Plastics as Carriers of Toxic Agents and Their Impact on Human Health

This review compiles evidence on how micro- and nanoplastics act as carriers of potentially toxic agents and enter the human body through inhalation, ingestion, and dermal absorption. Evidence indicates that continuous exposure to these particles can lead to bioaccumulation and negative health alterations, with recent research detecting microplastics even in human placental tissue.

2023 Environmental sciences 6 citations
Article Tier 2

Toxicokinetic Effects of Micro/Nano Plastics on Human Health

This review covers the toxicokinetics of micro- and nanoplastics in humans, examining how particles enter the body through ingestion, inhalation, and skin contact, distribute across organs via the circulatory system, and trigger cellular and biochemical responses at the tissue level.

2025
Article Tier 2

New insights in to the environmental behavior and ecological toxicity of microplastics

This review provides new insights into how microplastics behave in the environment and their toxic effects on living organisms. Microplastics can absorb and carry other pollutants, making them more dangerous than the plastic alone, and their effects vary based on size, shape, and chemical composition. The review highlights that smaller particles, especially nanoplastics, pose the greatest risk because they can cross biological barriers and enter cells.

2023 Journal of Hazardous Materials Advances 80 citations