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61,005 resultsShowing papers similar to Nanoparticles in Drug Delivery
ClearNanomaterials in Drug Delivery: Strengths and Opportunities in Medicine
This review covers how nanomaterials are being used to improve drug delivery for treating cancer and infections, offering better targeted therapy with fewer side effects. While not directly about microplastics, the research on how nanoparticles interact with human tissues provides insight into how similarly sized nanoplastics might behave once inside the body.
Advances in Drug Targeting, Drug Delivery, and Nanotechnology Applications: Therapeutic Significance in Cancer Treatment
This review covers advances in targeted drug delivery using nanotechnology, including nanoparticles and liposomes designed to release medications precisely where needed in the body. While focused on cancer treatment, the drug delivery technologies discussed are relevant to understanding how nanoscale plastic particles may also travel through the body and accumulate in specific tissues.
Polymer-based nanocarriers for biomedical and environmental applications
This review covers the fabrication, design, and applications of polymer-based nanocarriers in biomedical and environmental fields. The study highlights their use in targeted drug delivery and cancer therapy, as well as their ability to remove heavy metals and contaminants from air and water, while noting current challenges for future development.
Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases
This review examines biodegradable nanomaterials designed to deliver drugs precisely to treat autoimmune diseases, releasing medications in response to specific body signals like pH or temperature changes. While focused on drug delivery, the responsive behavior of these biodegradable nanoparticles in the body parallels how micro- and nanoplastics interact with biological systems and accumulate in tissues.
The Other Side of Plastics: Bioplastic-Based Nanoparticles for Drug Delivery Systems in the Brain
This review explores bioplastic-based nanoparticles as potential drug delivery vehicles for brain diseases, examining both their therapeutic promise and safety concerns. Researchers found that biodegradable polymers can pass through biological barriers and concentrate in specific tissues, making them useful for targeted drug delivery. However, the study cautions that the same properties enabling tissue penetration also raise concerns about long-term accumulation and unknown biological effects.
Hydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations
Researchers reviewed how nanoparticles embedded in hydrogels — water-based gel materials — can serve as targeted drug delivery vehicles for brain tumors by crossing the blood-brain barrier, a major obstacle that blocks most medications from reaching the brain. These systems have shown improved survival rates in studies, and the review outlines remaining challenges around manufacturing, stability, and scaling up for clinical use.
Evaluation of properties for synthetic polymers in medicine
This review examines the properties and biomedical applications of synthetic polymers, covering their use in drug delivery, tissue engineering, cardiovascular devices, and implants, with synthetic polymers accounting for the majority of new pharmaceutical and therapeutic research applications.
Nanotechnology in cancer treatment: revolutionizing strategies against drug resistance
This review explores how nanotechnology is being used to overcome drug resistance in cancer treatment, using materials like carbon nanotubes, dendrimers, and liposomes to deliver drugs more precisely to tumors. While not directly about microplastics, the nanomaterial strategies discussed share relevance with understanding how nano-sized plastic particles interact with human cells and tissues.
An updated overview of some factors that influence the biological effects of nanoparticles
This review provides an updated look at how the size, shape, chemical composition, and surface properties of nanoparticles influence their biological effects when they enter the body. Researchers summarize how these physical characteristics determine how nanoparticles interact with proteins, cell receptors, and other biological molecules. The study highlights the importance of understanding these factors for both the safe design of medical nanoparticles and for assessing environmental nanoparticle risks.
Artificial engineering of the protein corona at bio-nano interfaces for improved cancer-targeted nanotherapy
Researchers reviewed how engineering the protein corona — the layer of proteins that coats nanoparticles in biological fluids — through modifications like PEGylation and protein pre-coating can improve nanoparticle targeting for cancer drug delivery by controlling how immune cells recognize and clear the particles.
Biodegradable Nanoplastic: a Tool for Drug Delivery and Environmental Challenge
This review discusses the dual nature of biodegradable nanoplastics — their promise as targeted drug delivery vehicles due to their controllable surface chemistry, versus the environmental concern of uncontrolled nanoplastic accumulation from biodegradable polymer degradation in ecosystems.
Application of Hydrogel as Drug Carrier in Tumor Therapy
This review summarizes recent advances in hydrogel-based drug delivery systems for cancer therapy, focusing on their ability to achieve controlled drug release and respond to tumor microenvironment signals for targeted treatment.
Cellular journey of nanomaterials: Theories, trafficking, and kinetics
This review traces the cellular journey of engineered nanomaterials after they enter the human body, covering how particles cross cell membranes, travel through cellular compartments, and are either stored or expelled. Researchers found that a nanomaterial's size, shape, and surface chemistry all influence how cells process it. The study highlights the importance of understanding these cellular pathways for evaluating both the therapeutic potential and safety risks of nanomaterials.
The quest for nanoparticle-powered vaccines in cancer immunotherapy
This review explores how nanoparticles are being developed as cancer vaccine delivery systems to train the immune system to fight tumors more effectively. While focused on cancer immunotherapy rather than microplastics, the research highlights that understanding how nanoparticles interact with the immune system is crucial -- the same principles apply to understanding how nanoplastics may affect immune responses in the body.
Toxicological considerations of nano-sized plastics
This review examined the toxicological considerations specific to nanoplastics, focusing on how particle deposition in different biological compartments, physical properties (size, shape, surface chemistry), and chemical additives interact to determine biological effects. The authors argue that understanding nanoplastic toxicology requires shifting focus from exposure characterization to mechanistic biological relevance at the tissue and organ level.
Nanoteknolojinin Tıp ve Mühendislik Uygulamaları
This review covers nanotechnology applications in medicine and engineering, summarizing advancements in nanomaterial development and their utilization across biomedical and engineering domains.
Role of Polymers in Microfluidic Devices
This review examines how natural and synthetic polymers are used to fabricate microfluidic devices, highlighting their biocompatibility, tuneable properties, and applications in tissue engineering, drug delivery, and environmental monitoring platforms.
Insights into the toxicity of biomaterials microparticles with a combination of cellular and oxidative biomarkers
This study assessed the toxicity of biomaterial microparticles including natural and synthetic polymers using cellular viability and oxidative stress biomarkers, finding that particle type, size, and surface chemistry all influenced cytotoxic potential.
Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review
Researchers reviewed how the physical and chemical properties of nanoparticles — including size, shape, surface charge, and material type — influence their toxicity in living cells and tissues, with relevance to both medical applications and environmental exposures like nanoplastics. Smaller particles are generally more toxic because they have greater surface area and can more easily penetrate cell membranes and trigger oxidative stress.
Potential Toxicity of Nanoparticles for the Oral Delivery of Therapeutics
This chapter reviews the potential toxic effects of nanoparticles used for oral drug delivery, examining how properties like size, surface area, surface charge, and chemistry influence biological interactions. While nanoparticles offer advantages for drug bioavailability, their unexpected interactions with biological systems raise significant safety concerns.
Biomembrane-wrapped gene delivery nanoparticles for cancer therapy
This review examined biomembrane-wrapped nanoparticles as gene delivery vehicles for cancer therapy, highlighting how cell membrane coatings improve targeting, immune evasion, and therapeutic efficacy compared to conventional synthetic delivery systems.
Integrating Artificial Intelligence with Quality by Design in the Formulation of Lecithin/Chitosan Nanoparticles of a Poorly Water-Soluble Drug
This study used artificial intelligence and quality-by-design methods to create optimized nanoparticles for delivering a cancer-fighting drug called silymarin. While not directly about microplastics, the research advances understanding of how nanoparticles interact with biological systems, which is relevant because nanoplastics behave similarly in the body. The techniques developed here could help researchers better predict how nanoscale plastic particles are absorbed and distributed in human tissues.
Emerging Advanced Materials, Properties for Biomedical Applications
This is a materials science review covering advances in synthetic, natural, and hybrid biomaterials for medical applications such as drug delivery and artificial organs; it is not a microplastics research paper.
Bright and Stable Nanomaterials for Imaging and Sensing
This review covers strategies for developing bright and photostable fluorescent polymer nanoparticles for use in biological imaging and chemical sensing. Design approaches include loading many dye molecules per nanoparticle and coupling dyes to plasmonic nanostructures to amplify their light emission.