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Papers
61,005 resultsShowing papers similar to Integrated metabolomics and transcriptomics reveal the role of calcium sugar alcohol in the regulation of phenolic acid biosynthesis in Torreya grandis nuts
ClearMetabolic Profiling of Sugars and Organic Acids, and Expression Analyses of Metabolism-Associated Genes in Two Yellow-Peel Pitaya Species
Researchers profiled sugar and organic acid metabolism across fruit developmental stages in two yellow-peel pitaya species ('WCHL' Hylocereus undatus and 'YCHL' Hylocereus megalanthus), using metabolic and gene expression analyses to track accumulation of phenols, flavonoids, ascorbic acid, starch, and soluble sugars. The study identifies species-specific patterns in metabolite accumulation and associated gene expression that determine pitaya fruit quality.
Use of untargeted metabolomics to profile the foliar metabolome of Mitragyna speciosa under varying light and water conditions
Researchers used untargeted metabolomics to profile how light intensity and water availability shape the foliar chemistry of kratom seedlings, finding that high light reduced nitrogen-based alkaloids while increasing photoprotective compounds, and that low light combined with low water triggered an antioxidant stress response.
Integrative Physiological and Transcriptome Analysis Reveals the Mechanism of Cd Tolerance in Sinapis alba
This paper is not about microplastics; it uses transcriptomics and physiological measurements to understand how white mustard (Sinapis alba) tolerates cadmium heavy metal stress at the molecular level.
Widely Targeted Metabolomic Profiling Combined with Transcriptome Analysis Provides New Insights into Lipid Biosynthesis in Seed Kernels of Pinus koraiensis
Researchers used metabolomic profiling and transcriptome analysis to investigate lipid biosynthesis in Korean pine seed kernels at various developmental stages. The study identified key lipid metabolites including linoleic acid and alpha-linolenic acid that steadily increased during development, along with 10 hub genes involved in lipid synthesis, providing a foundation for understanding fatty acid metabolism in this nutritionally valued nut crop.
Metabolomics as a Tool to Understand Nano-Plant Interactions: The Case Study of Metal-Based Nanoparticles
This review highlights the underuse of metabolomics in studying how metal-based nanoparticles affect plant biology, summarizing available evidence on how nanoparticles alter plant metabolite profiles and reprogramming of metabolic pathways, with relevance to precision agriculture applications.
Unraveling the Complex Physiological, Biochemical, and Transcriptomic Responses of Pea Sprouts to Salinity Stress
Researchers investigated the physiological, biochemical, and transcriptomic responses of pea sprouts to high salinity stress, analyzing the ascorbic acid-glutathione cycle, endogenous hormone levels, metabolite profiles, and gene expression patterns. The study revealed coordinated redox-metabolic adjustments and transcriptome reprogramming that mediate ionic stress tolerance in this nutrient-rich crop.
Mechanism of P-Hydroxy Benzyl Alcohol Against Cerebral Ischemia Based on Metabonomics Analysis
Researchers investigated how p-hydroxybenzyl alcohol, an active compound from the traditional medicinal plant Gastrodia elata, protects against brain damage caused by reduced blood flow. Using metabolomics in cell and rat models, they identified that the compound works by improving mitochondrial function and reducing excessive autophagy through a specific signaling pathway. The study provides new molecular targets that could inform future treatments for cerebral ischemia.
Integration of transcriptomics and metabolomics reveals the mechanism of Lycium barbarum polysaccharides inhibited MCF-7 cell proliferation
Researchers used transcriptomics and metabolomics to investigate how Lycium barbarum polysaccharides inhibit MCF-7 breast cancer cell proliferation, identifying the molecular mechanisms and signaling pathways responsible for the compound's anticancer activity at an optimal dose of 8 mg/mL.
Systematic Identification of Bioactive Compositions in Leaves of Morus Cultivars Using UHPLC-ESI-QTOF-MS/MS and Comprehensive Screening of High-Quality Resources
Ultra-high-performance liquid chromatography coupled with mass spectrometry was used to systematically identify bioactive compounds in leaves from multiple Morus (mulberry) cultivars, revealing diverse phenolic acids, flavonoids, and alkaloids with metabolic health benefits. The study establishes a comprehensive chemical fingerprint for mulberry leaves and identifies high-quality cultivars for development as dietary supplements.
Nutrient Metabolism Pathways Analysis and Key Candidate Genes Identification Corresponding to Cadmium Stress in Buckwheat through Multiomics Analysis
This study used transcriptomic and metabolomic analysis to investigate how buckwheat responds to cadmium stress at the molecular level, identifying key metabolic pathways affected by the heavy metal. It is not about microplastics and is not relevant to microplastic research.
Transcriptomic Analysis Reveals the Flavonoid Biosynthesis Pathway Involved in Rhizome Development in Polygonatum cyrtonema Hua
Researchers used transcriptomic analysis to map the flavonoid biosynthesis pathways in the rhizomes of Polygonatum cyrtonema, a traditional medicinal plant. The study identified key genes and transcription factors involved in flavonoid accumulation, providing a molecular foundation for understanding how this plant produces compounds with antioxidant and other bioactive properties.
Growth, Stoichiometry, and Palatability of Suaeda salsa From Different Habitats Are Demonstrated by Differentially Expressed Proteins and Their Enriched Pathways
Two color variants of the halophyte Suaeda salsa show differences in growth and chemical composition linked to their intertidal versus inland habitats. Protein expression analysis revealed that habitat-driven stress responses shape the plant's nutritional and ecological properties.
Human Metabolism: A Regulatory Perspective
This paper provides a regulatory perspective on human metabolism, examining physiological and biochemical regulatory frameworks relevant to metabolic processes.
The Phosphoproteomic Response of Pepper (Capsicum annuum L.) Seedlings to Selenium Stress
Researchers investigated the phosphoproteomic response of pepper (Capsicum annuum L.) seedlings to excess selenium stress using Tandem Mass Tag quantitative proteomics, identifying 4,434 phosphorylation sites on 2,058 proteins. They found that upregulated phosphoproteins were strongly associated with phenylpropanoid biosynthesis and nicotinamide metabolism pathways, while downregulated proteins were linked to ABC transporters and plant hormone signalling, providing new insights into plant selenium toxicity mechanisms.
Dopamine alleviates cadmium stress in apple trees by recruiting beneficial microorganisms to enhance the physiological resilience revealed by high-throughput sequencing and soil metabolomics
Researchers found that applying dopamine to soil helped apple trees resist cadmium toxicity by reducing the accumulation of the heavy metal and harmful reactive oxygen species in the plants. The dopamine treatment also reshaped the soil microbial community, recruiting beneficial bacteria that further enhanced the trees' stress tolerance. The study suggests dopamine could serve as a practical tool for improving crop resilience in soils contaminated with heavy metals.
Interpreting the potential of biogenic TiO2 nanoparticles on enhancing soybean resilience to salinity via maintaining ion homeostasis and minimizing malondialdehyde
Researchers found that titanium dioxide nanoparticles derived from plants helped soybean crops tolerate salt stress by improving water retention, boosting antioxidant defenses, and keeping beneficial minerals like potassium in balance — offering a potential tool for farming in salt-affected soils.
Characteristics of Rhizosphere Microbiome, Soil Chemical Properties, and Plant Biomass and Nutrients in Citrus reticulata cv. Shatangju Exposed to Increasing Soil Cu Levels
This study characterized rhizosphere microbiome composition, soil chemical properties, and plant biochemistry in relation to soil management practices, finding that treatment type drives distinct rhizosphere microbial communities with functional consequences for plant health.
Nanoplastic toxicity induces metabolic shifts in Populus × euramericana cv. '74/76' revealed by multi-omics analysis
Researchers used transcriptomic and metabolomic profiling to show that polystyrene nanoplastics accumulate in poplar tree roots, penetrate chloroplasts in leaves causing photosynthesis disruption, and trigger a metabolic shift from normal growth to defensive flavonoid production under severe exposure conditions.
Exogenous ethephon treatment on the biosynthesis and accumulation of astragaloside IV in Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao
Researchers investigated how exogenous ethephon (an ethylene-releasing compound) affects the biosynthesis and accumulation of astragaloside IV in hydroponically cultivated Astragalus membranaceus, measuring both content and gene expression changes to understand how ethylene signaling regulates this key secondary metabolite.
Soil metabolomics: Deciphering underground metabolic webs in terrestrial ecosystems
Researchers reviewed how studying the chemical building blocks (metabolites) in soil can reveal how nutrients cycle through ecosystems and how soil health responds to pollution and climate stress. This approach helps scientists better understand the invisible underground networks that keep soils fertile and functioning.
Integrating the Soil Microbiota and Metabolome Reveals the Mechanism through Which Controlled Release Fertilizer Affects Sugarcane Growth
Researchers used soil microbial community profiling and metabolomics to investigate how controlled-release fertilizer application rates affect sugarcane growth. The study found that different fertilizer rates significantly influenced root-associated microbial communities and soil metabolite patterns, providing insights into optimizing fertilizer use for improved crop production.
A Perusal of Phenolics Within Polar Peel Fractions of Malus domestica var Maharaji via Hyphenated Techniques Cum Anti-microbial with REMA and Tyrosinase Inhibitory Potential thereof
Not relevant to microplastics — this paper characterizes phenolic compounds in apple peel extracts and evaluates their antibacterial and tyrosinase-inhibitory activities for potential pharmaceutical applications.
Metabolic and transcriptomic responses of Taxus mairei to nano-pollutants: insights into AgNPs and PsNPs impact
Taxus mairei plants exposed to polystyrene nanoplastics (PsNPs) and silver nanoparticles (AgNPs) showed distinct metabolic and transcriptomic responses, with both nano-pollutants disrupting primary and secondary metabolism—including taxol biosynthesis pathways—at different doses, with implications for medicinal plant cultivation in polluted environments.
Multiple Factors Jointly Lead to the Lower Soil Microbial Carbon Use Efficiency of Abies fanjingshanensis in a Typical Subtropical Forest in Southwest China
Researchers evaluated microbial carbon use efficiency (CUE) in the rhizospheric topsoil and subsoil of the endangered Abies fanjingshanensis at three elevations in a subtropical forest in southwest China, alongside physicochemical indices, enzyme activities, and microbial community composition. They found that pH was the most important factor controlling CUE, with acidic conditions forcing microorganisms to expend more energy on cellular pH maintenance rather than biomass production.