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The Phosphoproteomic Response of Pepper (Capsicum annuum L.) Seedlings to Selenium Stress

Horticulturae 2023 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 35 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Jiahua Wu, Shixian Guo, Jing Wang, Jiaojun He, Xingfu Li, Yihua Zhan

Summary

Researchers investigated the phosphoproteomic response of pepper (Capsicum annuum L.) seedlings to excess selenium stress using Tandem Mass Tag quantitative proteomics, identifying 4,434 phosphorylation sites on 2,058 proteins. They found that upregulated phosphoproteins were strongly associated with phenylpropanoid biosynthesis and nicotinamide metabolism pathways, while downregulated proteins were linked to ABC transporters and plant hormone signalling, providing new insights into plant selenium toxicity mechanisms.

Excessive selenium has gradually become a potential environmentally hazardous element for all organisms. Limited knowledge is available regarding the toxic mechanism of selenium in pepper, so the quantitative proteomics of phosphorylation was studied by Tandem Mass Tag approaches. A total of 4434 phosphorylation sites were identified on 2058 proteins, of which 3749 sites of 1919 proteins contained quantitative information. In the Se/mock (seedlings without Se treatment) comparison group, the number of upregulated phosphoproteins (658) was significantly higher than that of the downregulated ones (61). Systematic bioinformatics analysis, including protein annotation, functional classification, subcellular localization, and cluster analysis was performed. A total of 33 over-represented motifs were found in serine phosphorylation, and the most frequent motif was ‘sP’ (308 occurrences). According to KEGG enrichment analysis, the upregulated phosphorylated proteins (DPPs) were most strongly associated with the ’phenylpropanoid biosynthesis’ and ’nicotinate and nicotinamide metabolism’ pathways, while those that were downregulated were associated with the ’ABC transporters’ and ‘plant hormone signal transduction’ pathways. Our data can provide new insights for evaluating the response mechanism of plants to selenium pollution and improving their resistance to selenium.

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