Papers

20 results
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Article Tier 2

Charge-dependent negative effects of polystyrene nanoplastics on Oryzias melastigma under ocean acidification conditions

This study tested the combined effects of differentially charged polystyrene nanoplastics and ocean acidification on the marine fish Oryzias melastigma, finding that surface charge significantly influenced both independent and interactive toxicity. Negatively charged particles were generally more harmful, with effects exacerbated under acidified conditions.

2022 The Science of The Total Environment 14 citations
Article Tier 2

Synthesized effects of medium-term exposure to seawater acidification and microplastics on the physiology and energy budget of the thick shell mussel Mytilus coruscus

Researchers found that combined exposure to ocean acidification and microplastics significantly reduced the feeding rate, food absorption, and energy budget of the thick shell mussel Mytilus coruscus, with acidification amplifying the negative effects of microplastics.

2022 Environmental Pollution 20 citations
Article Tier 2

Genotoxicity and metabolic changes induced via ingestion of virgin and UV-aged polyethylene microplastics by the freshwater fish Perca fluviatilis

Freshwater perch fed UV-aged polyethylene microplastics showed greater DNA damage and more severe metabolic disruption in liver and muscle tissue than fish fed virgin (new) microplastics. The aged plastics disrupted energy metabolism, amino acid processing, and neurotransmitter levels. Since most microplastics in the environment have been weathered by sunlight, these findings suggest the real-world health risks to fish — and potentially to the humans who eat them — may be greater than lab studies using fresh plastics indicate.

2024 Chemosphere 19 citations
Article Tier 2

Aggravated VisualToxicity of Eco-Corona on Micro(Nano)Plasticsin Marine Medaka (Oryzias melastigma)

Researchers investigated how eco-corona formation—the coating of proteins and organic matter on micro- and nanoplastic surfaces in seawater—aggravated visual toxicity in marine medaka fish, finding that eco-corona altered particle uptake and enhanced phototoxic effects in ocular tissue.

2025 Figshare
Article Tier 2

Effects of ocean acidification and polystyrene microplastics on the oysters Crassostrea gigas: An integrated biomarker and metabolomic approach

Researchers exposed oysters to polystyrene microplastics of two sizes under both normal and acidified ocean conditions to simulate climate change. They found that ocean acidification and microplastics interacted in complex ways, with smaller microplastics under acidic conditions altering the oysters' metabolic profiles in their digestive organs. This study highlights that climate change may change how microplastics affect the shellfish many people eat.

2024 Marine Environmental Research 21 citations
Article Tier 2

Ocean acidification enhances microplastic uptake and alters physiological responses in Manila clams

Researchers found that ocean acidification (pH 7.6) impaired particle selection in Manila clams, leading to greater microplastic retention in the digestive tract, while filtration and respiration rates were maintained at higher levels under acidified conditions, suggesting suppressed stress responses and a synergistic interaction between ocean acidification and microplastic pollution.

2025 Marine Pollution Bulletin
Article Tier 2

Environmentally relevant concentrations of microplastics modulated the immune response and swimming activity, and impaired the development of marine medaka Oryzias melastigma larvae

Researchers found that environmentally relevant concentrations of microplastics impaired immune responses, swimming behavior, and larval development in marine medaka fish, demonstrating that even low-level exposure poses ecological risks.

2022 Ecotoxicology and Environmental Safety 30 citations
Article Tier 2

Effects of microplastics and phenanthrene on gut microbiome and metabolome alterations in the marine medaka Oryzias melastigma

Researchers exposed marine medaka fish to microplastics combined with phenanthrene, a common organic pollutant, and found that the combination disrupted gut bacteria and metabolism more than either substance alone. Specific gut bacterial communities shifted in response to the combined exposure, leading to changes in important metabolic processes. This study underscores that microplastics in the ocean don't act alone; they interact with other pollutants to amplify harm to aquatic organisms and potentially to the humans who consume seafood.

2023 Journal of Hazardous Materials 33 citations
Article Tier 2

Different effects of nano- and microplastics on oxidative status and gut microbiota in the marine medaka Oryzias melastigma

Researchers compared the effects of nanoplastics and microplastics on oxidative stress and gut microbiota in marine medaka fish. They found that nanoplastics caused more severe oxidative damage and greater disruption to the gut microbial community than larger microplastic particles. The study suggests that particle size plays a critical role in determining the biological impact of plastic pollution on aquatic organisms.

2020 Journal of Hazardous Materials 244 citations
Article Tier 2

Microplastics can aggravate the impact of ocean acidification on the health of mussels: Insights from physiological performance, immunity and byssus properties

Researchers found that the combination of ocean acidification and microplastic exposure weakened mussel immune systems, reduced feeding performance, and degraded the quality of byssus threads used for attachment. The study suggests that co-occurring ocean acidification and microplastic pollution could increase the vulnerability of bivalves to disease and dislodgement, threatening their survival in future marine environments.

2022 Environmental Pollution 69 citations
Article Tier 2

Impacts of microplastics and the associated plastisphere on physiological, biochemical, genetic expression and gut microbiota of the filter-feeder amphioxus

Researchers exposed filter-feeding amphioxus to weathered microplastics colonized by natural marine biofilms and found significant impacts on physiology, biochemistry, and gut microbiota under starvation conditions. The weathered plastics with their attached microbial communities caused more disruption than pristine particles typically used in lab studies. The findings suggest that real-world microplastic pollution, complete with its biofilm coating, may pose greater risks to marine filter feeders than laboratory experiments usually indicate.

2023 Environment International 35 citations
Article Tier 2

Oxidative stress and energy metabolic response of Isochrysis galbana induced by different types of pristine and aging microplastics and their leachates

Researchers compared how different types of pristine and aged microplastics affect a marine microalga used in aquaculture. Aged microplastics were more toxic than fresh ones, and the chemical compounds they released into the water caused greater oxidative stress and energy disruption in algal cells. The study suggests that as microplastics weather in the environment, they may become more harmful to the base of the marine food chain.

2023 Chemosphere 17 citations
Review Tier 2

Environmental behavior and toxic effects of micro(nano)plastics and engineered nanoparticles on marine organisms under ocean acidification: A review.

This review examined how ocean acidification interacts with the toxicity of micro- and nano-plastics and engineered nanoparticles in marine ecosystems, finding that lower pH can alter particle surface chemistry and enhance toxic effects in some organisms. The combined stressor perspective is important because climate change and plastic pollution are co-occurring in the same marine environments.

2024 Environmental research
Article Tier 2

Environmental samples of microplastics induce significant toxic effects in fish larvae

Researchers collected microplastic samples from beaches on Easter Island, Guam, and Hawaii, then fed them to Japanese medaka fish at concentrations reflecting real ocean conditions. Larvae exposed to these environmental microplastics experienced increased mortality, developmental abnormalities, DNA damage, and behavioral changes. The study demonstrates that realistic concentrations of weathered, real-world microplastics can cause significant harm to fish during their most vulnerable early life stages.

2019 Environment International 407 citations
Article Tier 2

Multigenerational effects of combined exposure of triphenyltin and micro/nanoplastics on marine medaka (Oryzias melastigma): From molecular levels to behavioral response

This study exposed marine medaka fish to a combination of micro/nanoplastics and triphenyltin, a toxic chemical used in paints and plastics. The pollutants caused oxidative stress, hormone imbalances, and behavioral changes that carried over to the next generation of fish. The findings show that microplastics combined with other environmental pollutants can cause harm that gets passed down to offspring, raising concerns about long-term effects on marine food webs.

2024 Journal of Hazardous Materials 14 citations
Article Tier 2

Investigating the metabolic and oxidative stress induced by biofouled microplastics exposure in Seriola lalandi (yellowtail kingfish)

This study tested how microplastics covered in natural ocean bacteria (biofouled) affect yellowtail kingfish compared to clean microplastics. The biofouled microplastics caused more oxidative stress and metabolic disruption in the fish than clean ones. Since fish in the wild almost always encounter bacteria-coated microplastics rather than clean ones, previous studies using only clean plastics may have underestimated the real health risks.

2024 Marine Pollution Bulletin 10 citations
Article Tier 2

The Influence of Ocean Acidification on The Surface Alteration of Microplastics

Researchers exposed virgin microplastics to normal seawater (pH 8.0) and acidified seawater (pH 7.7) for 10 days, using field emission scanning electron microscopy to show that ocean acidification accelerates surface aging and physical damage to microplastic particles, suggesting that increasing ocean acidity may enhance chemical leaching from plastics.

2022 Asian Journal of Fundamental and Applied Sciences 3 citations
Article Tier 2

Transgenerational effects of microplastics on Nrf2 signaling, GH/IGF, and HPI axis in marine medaka Oryzias melastigma under different salinities

Researchers exposed marine medaka fish to microplastics under different salt concentrations and tracked effects across two generations. They found that microplastic exposure impaired growth, disrupted antioxidant defenses, and altered stress hormone pathways, with effects persisting into the unexposed second generation. Higher salinity appeared to worsen the impacts, suggesting that saltwater fish may be more vulnerable to microplastic toxicity than those in lower-salinity environments.

2023 The Science of The Total Environment 17 citations
Article Tier 2

Polyethylene microplastic exposure and concurrent effect with Aeromonas hydrophila infection on zebrafish

Researchers found that polyethylene microplastic exposure in zebrafish caused oxidative stress, altered antioxidant enzyme activity, and induced intestinal damage, with concurrent Aeromonas hydrophila infection amplifying these toxic effects and increasing mortality rates.

2022 Environmental Science and Pollution Research 28 citations
Article Tier 2

Assessment of intake and effect of microplastics and its combination with metals in experimental (Daphnia magna) and environmental conditions (freshwater fish)

Researchers assessed the intake and effects of microplastics and their combination with metals using Daphnia magna as an experimental model and freshwater fish under environmental conditions, investigating how microplastics adsorb and transport harmful metals in freshwater systems.

2025 Repository of Faculty of Chemical Engineering and Technology University of Zagreb