Papers

20 results
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Article Tier 2

Comprehensive profiling and risk assessment of antibiotic resistomes in surface water and plastisphere by integrated shotgun metagenomics

Researchers used shotgun metagenomics to compare antibiotic resistance genes in surface water versus the biofilms that form on microplastic surfaces, known as the plastisphere. They found that microplastics harbored distinct microbial communities with different antibiotic resistance profiles compared to surrounding water. The study raises concerns that microplastics may serve as vehicles for spreading antibiotic resistance in aquatic environments.

2025 Journal of Hazardous Materials 13 citations
Meta Analysis Tier 1

Microplastisphere may induce the enrichment of antibiotic resistance genes on microplastics in aquatic environments: A review

This first meta-analysis of antibiotic resistance gene (ARG) enrichment on microplastics found that ARGs were more abundant on microplastic surfaces than on inorganic substrates or in surrounding water, but less abundant than on natural organic substrates. Freshwater microplastics showed a higher degree of ARG enrichment than those in saline water or sewage.

2022 Environmental Pollution 76 citations
Article Tier 2

Microplastisphere antibiotic resistance genes: A bird's-eye view on the plastic-specific diversity and enrichment

Microplastics in the environment act as surfaces for microbial communities called microplastispheres, which this review finds are enriched with antibiotic resistance genes (ARGs). The type of plastic, surrounding water chemistry, and co-occurring pollutants all influence which resistance genes accumulate, raising concern that microplastics could be spreading antibiotic resistance through aquatic environments worldwide.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Metagenomic insights into ecological risk of antibiotic resistome and mobilome in riverine plastisphere under impact of urbanization

This study used advanced genetic sequencing to examine antibiotic resistance genes on microplastics found in an urban river. Microplastics harbored more antibiotic resistance genes and mobile genetic elements than natural materials like rocks and wood, and the problem was worse in more urbanized areas. The findings suggest that microplastics in waterways can act as hotspots for spreading antibiotic resistance, which is a growing public health threat.

2024 Environment International 11 citations
Systematic Review Tier 1

The Plastisphere Resistome: A Systematic Review of Antibiotic Resistance Genes and Resistant Bacteria on Microplastics

This systematic review examines whether microplastic-associated biofilms harbor higher levels of antibiotic-resistant bacteria compared to surrounding environments. If microplastics act as hotspots for antibiotic resistance genes, they could spread drug-resistant bacteria through water systems, posing a serious concern for human health and the effectiveness of antibiotics.

2026 Open Science Framework
Article Tier 2

DeterminingAntimicrobial Resistance in the Plastisphere:Lower Risks of Nonbiodegradable vs Higher Risks of Biodegradable Microplastics

Researchers determined the prevalence and diversity of antimicrobial resistance genes in the plastisphere (biofilm on microplastics) compared to surrounding water and sediment, finding that non-biodegradable plastics hosted distinct resistance gene profiles with lower overall resistance risk than biodegradable plastic surfaces.

2025 Figshare
Article Tier 2

Deciphering the mechanisms shaping the plastisphere antibiotic resistome on riverine microplastics

Researchers found that microplastics in China's Huangpu River selectively enrich antibiotic resistance genes for Rifamycin and Vancomycin, creating unique bacterial niches that favor horizontal gene transfer and dissemination of resistance through stochastic assembly processes.

2022 Water Research 87 citations
Article Tier 2

Antibiotic resistance in plastisphere

Researchers reviewed antibiotic resistance in the plastisphere — the microbial community colonizing plastic surfaces in aquatic environments — finding that plastic properties and aging influence the enrichment and horizontal transfer of antibiotic resistance genes, and that aged microplastics pose elevated risks due to increased adsorption of resistant bacteria.

2024 Journal of environmental chemical engineering 5 citations
Article Tier 2

Plastics in the marine environment are reservoirs for antibiotic and metal resistance genes

Metagenomic analysis of microbial communities on plastic particles from the North Pacific Gyre revealed high abundances of antibiotic resistance genes (ARGs) and metal resistance genes (MRGs) compared to surrounding seawater. The study demonstrates that ocean plastic debris functions as a reservoir and potential long-range vector for resistance genes, posing a global health concern.

2018 Environment International 448 citations
Article Tier 2

Microplastics can selectively enrich intracellular and extracellular antibiotic resistant genes and shape different microbial communities in aquatic systems

Researchers examined how microplastics of different types selectively capture antibiotic resistance genes and shape microbial communities in aquatic systems. They found that microplastics enriched both intracellular and extracellular antibiotic resistance genes, with the enrichment patterns varying by plastic type. The study suggests that microplastics may serve as hotspots for the spread of antimicrobial resistance in wastewater and natural water environments.

2022 The Science of The Total Environment 47 citations
Article Tier 2

Impact of Urbanization on Antibiotic Resistome in Different Microplastics: Evidence from a Large-Scale Whole River Analysis

Researchers conducted a large-scale river survey across urbanization gradients and characterized antibiotic resistance genes on microplastics from each zone, finding that urbanization level strongly predicted the diversity and abundance of resistance genes on plastic surfaces.

2021 Environmental Science & Technology 100 citations
Article Tier 2

Reshaping the antibiotic resistance genes in plastisphere upon deposition in sediment-water interface: Dynamic evolution and propagation mechanism

Researchers examined how antibiotic resistance genes in the microplastic biofilm (plastisphere) evolve as MPs settle from water to sediment, finding that deposition in sediment reshapes ARG profiles and promotes horizontal gene transfer, amplifying resistance gene reservoirs in benthic environments.

2025 Journal of Hazardous Materials 3 citations
Article Tier 2

Parity in bacterial communities and resistomes: Microplastic and natural organic particles in the Tyrrhenian Sea

Bacterial communities and antibiotic resistance genes on microplastic particles and natural organic particles in the Tyrrhenian Sea were found to be surprisingly similar, suggesting that microplastics may not selectively enrich for resistance genes in this context.

2024 Marine Pollution Bulletin 9 citations
Article Tier 2

Unraveling the role of microplastics in antibiotic resistance: Insights from long-read metagenomics on ARG mobility and host dynamics

Researchers used long-read metagenomics to investigate how microplastics serve as vectors for antibiotic resistance genes in aquatic environments. They found that plasmid-encoded resistance genes varied significantly between microplastic biofilms and surrounding water, highlighting horizontal gene transfer as a key mechanism for resistance gene enrichment on plastic surfaces. The study identified specific bacterial taxa driving this enrichment and revealed that enhanced cell adhesion and transporter activity on microplastics facilitate the spread of antibiotic resistance.

2025 Journal of Hazardous Materials 5 citations
Article Tier 2

Plastiome: Plastisphere-enriched mobile resistome in aquatic environments

Researchers studying two Japanese rivers near Tokyo found that microplastics floating in the water carry communities of bacteria harboring antibiotic resistance genes that can be transferred between organisms. This collection of mobile resistance genes on plastics, which they call the "plastiome," could help spread antibiotic resistance through waterways, posing an indirect but significant threat to human health.

2024 Journal of Hazardous Materials 20 citations
Article Tier 2

Microplastics and Their Role in the Maintenance and Spread of Antibiotic Resistance Genes in Marine Ecosystems

This review examines the role of microplastics in maintaining and spreading antibiotic resistance genes in marine ecosystems, synthesizing evidence that plastic pollution in aquatic environments creates reservoirs for antimicrobial resistant bacteria and facilitates horizontal gene transfer.

2022 Antibiot Khimioter = Antibiotics and Chemotherapy 1 citations
Article Tier 2

Microplastics: Disseminators of antibiotic resistance genes and pathogenic bacteria

This review examined the role of microplastics as carriers of antibiotic resistance genes (ARGs) and pathogenic bacteria, analyzing how plastisphere biofilms concentrate and spread AMR through air, water, and soil environments. The evidence supports MPs as global vectors for antimicrobial resistance dissemination with implications for human health.

2025 Aquatic Toxicology
Article Tier 2

New insight into the effect of microplastics on antibiotic resistance and bacterial community of biofilm

Researchers found that different types of microplastics promote distinct biofilm communities and enhance antibiotic resistance gene proliferation compared to natural substrates, suggesting microplastics serve as unique platforms for the spread of antimicrobial resistance.

2023 Chemosphere 30 citations
Article Tier 2

DeterminingAntimicrobial Resistance in the Plastisphere:Lower Risks of Nonbiodegradable vs Higher Risks of Biodegradable Microplastics

This companion study further characterizes antimicrobial resistance in the plastisphere across different plastic types, confirming that polymer biodegradability influences bacterial community composition and the enrichment of resistance determinants on plastic surfaces in aquatic environments.

2025 Figshare
Article Tier 2

Selective enrichment of antibiotic resistome and bacterial pathogens by aquatic microplastics

This review found that microplastics in aquatic environments selectively enrich antibiotic-resistant bacteria, resistance genes, and bacterial pathogens in their biofilms, making plastic debris a potential vector for spreading antimicrobial resistance.

2022 Journal of Hazardous Materials Advances 27 citations