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Papers
61,005 resultsShowing papers similar to Digital Nano-Plastic Science (DNPS) Paradigm: Computational Intelligence and Proteostasis Disruptions.
ClearDigital Nano-Plastic Science (DNPS) Paradigm: Computational Intelligence and Proteostasis Disruptions.
This paper presents a theoretical framework called Digital Nano-Plastic Science that applies computational modeling to understand how nanoplastics disrupt biological processes at the molecular level. The framework proposes new risk assessment tools including digital twin simulations for tracking environmental contamination and bioremediation outcomes. The work is intended as a policy-oriented white paper aligning nanoplastic research with UN Sustainable Development Goals.
Science-society-policy interface for microplastic and nanoplastic: Environmental and biomedical aspects
This review proposed a new conceptual framework for addressing microplastic and nanoplastic pollution at the science-society-policy interface, covering detection methods, environmental and health impacts, and regulatory approaches.
Biology in the 21st-Century: Transformation in biology science and education in supporting the sustainable development goals
This literature review examines how "New Biology" - the integration of biology with data science, engineering, and sustainability science - can contribute to achieving multiple UN Sustainable Development Goals including zero hunger, clean water, and good health. The study is relevant to microplastics research as it highlights how interdisciplinary biological sciences are increasingly needed to address environmental pollution and its health consequences.
Paradigms to assess the human health risks of nano- and microplastics
Researchers proposed a new, comprehensive framework for assessing the health risks of nano- and microplastics (tiny plastic particles), addressing key gaps in how we analyze these particles, model their behavior, and use that information to protect human health — since no such standard risk assessment system currently exists.
In vivo , in vitro , and in silico toxicology studies of nanoplastics and their modeling
This in vivo, in vitro, and in silico study assessed nanoplastic toxicity through multiple complementary methods, finding concentration-dependent toxic effects on cellular and organismal endpoints and using computational modeling to predict interaction mechanisms relevant to nanoplastic risk assessment.
Nano-plastics and their analytical characterisation and fate in the marine environment: From source to sea
Researchers reviewed the sources, environmental fate, organism interactions, and analytical detection methods for nano-sized plastic polymers in the marine environment, concluding that nanoplastics pose the greatest ecological risk among plastic size fractions and that standardized analytical protocols for nanoplastic characterization are urgently needed.
Micro/nanoplastics as environmental mediators: A systematic review of sources and interfacial processes driving cross-media transport and impacts
This systematic review advances a process-based framework for understanding how micro- and nanoplastics move between terrestrial, aquatic, and atmospheric environments. The findings reveal that cross-media transport pathways are poorly integrated in existing research, meaning the full scope of human exposure to microplastics across environmental compartments is likely underestimated.
Innovative Multi-omic Strategies to Explore Micro- and Nanoplastic Effects
This conference abstract proposes a multi-omic integration framework — combining transcriptomics, proteomics, metabolomics, and lipidomics — as a more comprehensive approach to characterizing biological responses to micro- and nanoplastic exposures than single-level analyses.
Microplastic toxicity: mechanisms, assessment methods, and future research directions
This review synthesizes current knowledge on microplastic toxicity mechanisms, integrating physical, chemical, and biological pathways into a unified framework. Researchers examined assessment methods across aquatic organisms, terrestrial species, and human cell models, identifying critical knowledge gaps and recommending standardized approaches for future microplastic toxicity research.
Toxicological review of micro- and nano-plastics in aquatic environments: Risks to ecosystems, food web dynamics and human health.
This review synthesized evidence on the toxicological effects of micro- and nanoplastics in aquatic ecosystems, covering risks to individual organisms, disruptions to food web dynamics, and pathways through which plastic exposure poses risks to human health via seafood consumption.
Leveraging nanoparticle environmental health and safety research in the study of micro- and nano-plastics
Researchers argue that two decades of research on the environmental health and safety of engineered nanomaterials provides a strong foundation for studying micro- and nanoplastics. They outline how lessons from nano-safety research apply to understanding plastic particle toxicity, bioaccumulation, trophic transfer, and environmental behavior. The study emphasizes that existing tools and methodologies from nanotoxicology can accelerate progress in assessing the risks of particulate plastic pollution.
Behavior and Bio-Interactions of Anthropogenic Particles in Marine Environment for a More Realistic Ecological Risk Assessment
This review examines how anthropogenic nanoparticles — including plastic fragments and engineered nanomaterials — behave in marine environments and interact with biology, arguing for more realistic multi-stressor exposure conditions in ecological risk assessment.
Global plastic footprint: unveiling property trends, environmental fate, and emerging threats of microplastic and nanoplastics pollution across ecosystems
This large-scale review of 228 studies maps how microplastics and nanoplastics spread through marine, freshwater, soil, and air environments worldwide. The research reveals emerging threats including plastics carrying disease-causing pathogens, interfering with ocean carbon capture, and accelerating ice melting, all of which have indirect consequences for human health and food safety.
A Multilevel Risk Assessment Framework for Nanoplastics in Aquatic Ecosystems
Researchers proposed a multilevel risk assessment framework for nanoplastics in aquatic ecosystems that synthesizes complex ecotoxicological datasets into actionable risk indicators, designed to help policymakers set safety thresholds and make decisions about restrictions on petrochemical-derived materials.
Nanoplastics as a return to the prebiotic dimensional regime: A dimensional perspective on interactions with biological membranes
This paper offers a dimensional perspective on nanoplastic-membrane interactions, arguing that nanoplastics occupy the same size range as early prebiotic structures and can physically integrate with or disrupt lipid bilayers. The framework suggests that physical membrane perturbation — independent of chemical toxicity — is central to nanoplastic health risks.
The scientific basis for addressing marine micro- and nanoplastic pollution: Informing effective monitoring and remediation frameworks
This review synthesizes the scientific basis for monitoring and remediating marine micro- and nanoplastic pollution, covering detection technologies, ecotoxicological effects across the food web, and the specific challenges nanoplastics pose due to their nanoscale properties.
Health impacts of micro- and nanoplastics: key influencing factors, limitations, and future perspectives
This review systematically analyzed how the physicochemical properties of micro- and nanoplastics — including size, shape, surface charge, and polymer type — determine their toxicological impacts across biological systems. The authors argue that property-based frameworks are essential for predicting MNP health risks and designing relevant research.
An integrated chemical engineering approach to understanding microplastics
Researchers proposed an integrated chemical engineering approach combining artificial intelligence, theoretical methods, and experimental techniques to better understand microplastic properties and behavior. The study suggests that the broad scope of chemical engineering makes it well-suited for characterizing microplastics and addressing the complexity of their environmental and health effects.
The organism fate of inland freshwater system under micro-/nano-plastic pollution: A review of past decade.
This review synthesized a decade of research on how micro- and nano-plastics affect freshwater organisms including microalgae, macrophytes, zooplankton, benthic invertebrates, and fish, finding that impacts range from impaired photosynthesis and oxidative stress to reproductive disruption and behavioral changes across multiple biological levels.
Multi-Omics Approach on the Ecotoxicological Assessment of Microplastics
This review examines the application of multi-omics approaches — including genomics, transcriptomics, proteomics, and metabolomics — to the ecotoxicological assessment of microplastics in living organisms. The authors synthesize how these integrated molecular tools are advancing understanding of the mechanistic pathways by which microplastics disrupt biological systems, offering a more comprehensive picture than single-endpoint toxicity studies.
Pollution caused by nanoplastics: adverse effects and mechanisms of interaction via molecular simulation
This review used molecular simulation techniques to examine how nanoplastics interact with biological membranes and proteins, finding that NPs alter lipid membrane organization and protein secondary structure, potentially disrupting digestion and nutrient absorption in the gastrointestinal system. The review synthesized evidence that NPs can also adsorb environmental contaminants and potentiate their toxicity through synergistic mechanisms.
A critical viewpoint on current issues, limitations, and future research needs on micro- and nanoplastic studies: From the detection to the toxicological assessment.
This critical review examines the current methods for detecting and characterizing micro- and nanoplastics in various environmental samples, as well as reported toxic effects from in vivo and in vitro studies. The authors found that while substantial effort has been made to understand microplastic behavior, the scientific community is still far from a complete understanding of how these particles behave in biological systems. The review calls for improved standardized protocols and more studies focused on uptake kinetics, accumulation, and biodistribution.
Micro- and Nano-Plastics Contaminants in the Environment: Sources, Fate, Toxicity, Detection, Remediation, and Sustainable Perspectives
This review provides a broad overview of micro- and nanoplastic pollution, covering where these particles come from, how they spread through the environment, and the damage they cause to living things including humans. The authors also compare different methods for removing microplastics from the environment, including physical, chemical, and biological approaches. The paper calls for more research and global cooperation to develop better tools for measuring the health risks of plastic pollution.
Micro- and nanoplastics: origin, sources of intake and impact on human health (literature review)
This literature review synthesizes mechanisms by which micro- and nanoplastics interact with living organisms, examining their physicochemical properties, routes of human exposure, and documented health effects across multiple organ systems.