Author response for "A Western-style diet shapes the gut and liver responses to low-dose, fit-for-purpose polystyrene nanoplastics in mice"

A Western-style diet shapes the gut and liver responses to low-dose, fit-for-purpose polystyrene nanoplastics in mice

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A subchronic mouse study found that low-dose polystyrene nanoplastics designed to mimic real-world particle characteristics impaired gut and liver health in a non-monotonic, diet-dependent manner, with Western-style diet amplifying the effects.

Impact of Micro-nanoplastics on Gut and Immune Function

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This review examined how micro- and nanoplastics disrupt gut microbiota and immune function across aquatic and terrestrial vertebrates, with implications for human health. Because the gut microbiome governs immune regulation and metabolic health, microplastic-induced dysbiosis represents a plausible mechanism by which plastic ingestion could drive systemic inflammation and disease beyond the GI tract.

Author response for "Polystyrene Nanoplastic Exposure Promotes Amyloid Misfolding and Metabolic Impairment at Sub-Lethal Doses. A Subcellular Infrared Imaging Study"

Impact of Microplastics on the Severity of Intestinal Inflammation in Mice

In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice.

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Mice orally exposed to polystyrene or mixed polymer microspheres showed plastic particle distribution across multiple tissues including the liver, kidney, and spleen, with metabolomic analysis revealing distinct alterations in lipid, amino acid, and energy metabolism pathways.