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Polystyrene Microplastics Disrupt Female Reproductive Health and Fertility Via Sirt1 Modulation in Zebrafish (Danio Rerio)
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Polystyrene microplastics disrupt female reproductive health and fertility via sirt1 modulation in zebrafish (Danio rerio)
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This study found that polystyrene microplastics disrupted female reproductive health in zebrafish by interfering with a key protein called SIRT1 that regulates hormone production. Exposed fish showed changes in egg development, hormone levels, and ovarian tissue structure. Since the hormonal pathways affected are similar in humans, these findings raise concerns about how microplastic exposure might contribute to fertility problems in women.
Microplastics induce polycystic ovary syndrome in zebrafish
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Researchers exposed zebrafish to microplastics and found the particles induced polycystic ovary syndrome (PCOS)-like conditions, suggesting this aquatic model could offer new approaches for assessing microplastic risks to women's reproductive health.
The Impact of Microplastic Pollution on the Reproduction and Development of Marine Fish: A Case Study of Zebrafish
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Researchers investigated how microplastic exposure affects zebrafish reproduction and offspring development, finding disruptions to gonadal tissue, reduced fertilization rates, and developmental abnormalities in embryos, offering a controlled model for understanding plastic pollution risks to marine fish populations.
Impact of Microplastics on Reproductive and Physiological Aspects of Aquatic Inhabitants
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Researchers reviewed how microplastic exposure affects reproduction and physiology in freshwater aquatic organisms, finding that plastic particles disrupt hormonal signaling, reduce fertility, and impair development across a range of sensitive freshwater species.
Recent advances of microplastics toxicity and fate on zebrafish-a review
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This review synthesizes evidence on how micro- and nanoplastics cause developmental, reproductive, gastrointestinal, and oxidative stress toxicity in zebrafish, positioning the species as a valuable vertebrate model for understanding plastic pollutant effects across trophic levels. Zebrafish research is accelerating mechanistic understanding of how microplastics harm vertebrate biology, providing insights relevant to assessing risks for fish-eating wildlife and humans.
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