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Microplastics induce polycystic ovary syndrome in zebrafish
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Researchers exposed zebrafish to microplastics and found the particles induced polycystic ovary syndrome (PCOS)-like conditions, suggesting this aquatic model could offer new approaches for assessing microplastic risks to women's reproductive health.
Could lead to new ways of assessing risk to women’s fertility Could lead to new ways of assessing risk to women’s fertility
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The Impact of Microplastic Pollution on the Reproduction and Development of Marine Fish: A Case Study of Zebrafish
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Researchers investigated how microplastic exposure affects zebrafish reproduction and offspring development, finding disruptions to gonadal tissue, reduced fertilization rates, and developmental abnormalities in embryos, offering a controlled model for understanding plastic pollution risks to marine fish populations.
Physiological Alterations and Immune Modulation in Fish Exposed to Microplastics
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Researchers reviewed the physiological and immunological effects of microplastic exposure in fish, finding that these particles smaller than 5 mm induce a range of biological disruptions including immune modulation, oxidative stress, and systemic health impacts with broader implications for aquatic ecosystem integrity.
Recent advances of microplastics toxicity and fate on zebrafish-a review
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This review synthesizes evidence on how micro- and nanoplastics cause developmental, reproductive, gastrointestinal, and oxidative stress toxicity in zebrafish, positioning the species as a valuable vertebrate model for understanding plastic pollutant effects across trophic levels. Zebrafish research is accelerating mechanistic understanding of how microplastics harm vertebrate biology, providing insights relevant to assessing risks for fish-eating wildlife and humans.
Acute Effects of Size Dependent Low-Density Polyethylene Microplastics on Zebrafish
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Zebrafish embryos exposed to low-density polyethylene microplastics for 48 hours accumulated particles in their gut, experienced reduced hatching rates, increased heart rates, and significant tissue damage, with smaller particles causing the most harm. These acute effects in a widely used model organism suggest that even brief early-life exposure to plastic particles can disrupt normal development.
Toxicity and behavioral response of zebrafish exposed to combined microplastic and bisphenol analogues
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Co-exposure of zebrafish larvae to polystyrene microplastics combined with bisphenol A or F increased larval lethality by 7–51% compared to either pollutant alone, while also causing stronger behavioral effects including reduced movement and activity. This synergistic toxicity — not seen in embryos — highlights the danger of treating microplastics and chemical contaminants as independent hazards, since real-world exposures are always mixed.
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