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Polycarbonate nanoplastics and the in vitro assessment of their toxicological impact on liver functionality

Environmental Science Nano 2023 7 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Valentina Tolardo, Alessio Romaldini, Francesco Fumagalli, Andrea Armirotti, Marina Veronesi, Davide Magrì, Stefania Sabella, Athanassia Athanassiou, Despina Fragouli

Summary

Researchers found that polycarbonate nanoplastics and molecular by-products formed during photodegradation both induce toxicity toward hepatocellular functions in liver cell models, demonstrating dual harmful effects from a single degradation process.

Polymers
Body Systems
Study Type In vitro

Polycarbonate photodegradation products, namely nanoplastics and molecular by-products, are formed in a single step. Studying their effects in a suitable hepatic model proves that both components induce toxicity toward hepatocellular functions.

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