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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Human Health Effects
Nanoplastics
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Hepatotoxic Mechanisms of Micro- and Nanoplastics in Animal Models: A Scoping Review with Human Health Implications
OSF Preprints (OSF Preprints)
2025
Noé López-Amador,
Ana Laura Calderón Garcidueñas,
Mario Alfonso Luna Palacios,
Rubén Ruiz Ramos,
Francisco Ruíz García,
Armando Pimentel Toledano,
Julio César Viñas Dozal
Summary
This scoping review examines hepatotoxic mechanisms of micro- and nanoplastics in animal models, identifying oxidative stress, inflammation, lipid peroxidation, and epigenetic alterations as the primary pathways through which plastic particles damage liver tissue.
Body Systems
This project aims to synthesize existing evidence on hepatotoxic mechanisms of micro- and nanoplastics in animal models and explore implications for human health.