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Tiny microplastics tremendous perils: Exploring the health burden of microplastics

International Journal of Biology Sciences 2025
Prasad Ankita B, Prasad Ankita B, Shelar Payal K, Joshi Pooja S, Mandole Anjali C, Shinde Nitin G

Summary

This review examined the health impacts of microplastics smaller than 5 mm across multiple organ systems, summarizing mechanisms of toxicity including oxidative stress, inflammation, endocrine disruption, and the transport of harmful chemical additives.

Microplastics, defined as plastic particles smaller than 5 millimetres, have raised environmental concerns due to their widespread distribution and potential health risks. This abstract aims to provide a comprehensive overview of the health impacts of microplastics and their systemic toxic effects. The research objective is to understand the mechanisms of toxicity and the specific health conditions associated with microplastic exposure. The methodology includes a review of relevant studies and scientific observations. The key findings reveal that microplastics can lead to respiratory issues, gastrointestinal dysbiosis, hepatotoxicity, renal toxicity, cardiovascular diseases, neurotoxicity, reproductive and developmental toxicity, endocrine disruptions, hormonal imbalances, metabolic disruptions, and is a potential carcinogen. The main implications are the need for reducing plastic consumption, improving waste management, promoting biodegradable alternatives, and implementing stringent policies to curb microplastic production. Overall, this research emphasizes the importance of addressing the health risks posed by microplastics and implementing effective mitigation strategies.

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