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Microbial Enzymes Involved in Plastic Degradation

2026
Bhumit Chavda, Yash Babaria

Summary

Scientists are studying special enzymes made by bacteria and fungi that can break down plastic waste—including common types like water bottles and food packaging—into harmless building blocks, offering a cleaner alternative to burning or burying plastic. This matters because less plastic waste in our environment means fewer microplastics breaking off into our water, food, and eventually our bodies, where they've been linked to health concerns. This review paper summarizes existing research on the topic, noting that while the science is promising, challenges remain before this approach can be used on a large scale.

Increasing global plastic pollution calls for sustainable measures, and microbial degradation is a glimpse of hope. This chapter focuses on the significant role of microbial enzymes in decomposing non-degradable synthetic polymers such as polyethylene, polypropylene, polystyrene, and polyethylene terephthalate (PET) into low–molecular weight molecules that are in a state of digestibility. These enzymes break plastic's bonds, achieving depolymerization for PET under ambient conditions with PETases and cutinases and laccases for complex aromatics. There are such factors as plastic compositions, environmental conditions, and microbial metabolic abilities to facilitate the efficiency of enzymatic breakdown. New and more functional plastic-degrading enzymes have been identified and produced through the advancement in metagenomics, proteomics, and synthetic biology, from different environments. Genomic studies reveal vital gene clusters and metabolic pathways while enhancing stagnation and enzyme activity for commercial purposes employing protein engineering. The biotechnological usage of these enzymes brings opportunities for bioremediation, waste valorization, and circular plastic economy, and enzymatic PET recycling is a low-energy alternative to chemical processes. With the advancements in science, some problems exist, such as the enzyme suppression by additives, slow breakdown rates on certain polymers, as well as scaling up lab findings. Future studies should focus on the development of robust microbial foundations, stable enzymes, and flexible in situ bioremediation strategies, including policy integration and interdisciplinary collaboration to transform the scientific attainments into significant environmental outcomes. The utilization of microbial enzymes is an eco-friendly way to address the global plastic calamity, coming together in a consortium of microbiology, biotechnology, and environmental science for inventive rubbish.

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