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Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism
Journal of Bioengineering, Technologies and Health
2023
30 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Juan Ma,
Yin Wan,
Lingmin Song,
Luchen Wang,
Huimei Wang,
Yingzhi Li,
Danfei Huang
Summary
Researchers found that polystyrene nanoparticles worsen chronic colitis in mice by inducing oxidative stress and disrupting hepatic lipid metabolism, suggesting that populations with existing inflammatory bowel conditions face heightened vulnerability to microplastic exposure.
PS-NPs exacerbate intestinal inflammation and injury in mice with chronic colitis. This finding highlights chronically ill populations' susceptibility to environmental hazards, which urgent more research and risk assessment studies.