Papers

61,005 results
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Article Tier 2

Micro problems with macro consequences: accumulation of persistent organic pollutants and microplastics in human breast milk and in human milk substitutes

This review examines the presence of persistent organic pollutants and microplastics in both human breast milk and infant formula, raising questions about early-life exposure. Researchers found that these contaminants can transfer to infants during the critical first 1,000 days of development, a period important for long-term health. The study highlights significant gaps in our understanding of how combined exposure to microplastics and organic pollutants during infancy may affect health outcomes.

2023 Environmental Science and Pollution Research 28 citations
Article Tier 2

Maternal and early life exposures and their potential to influence development of the microbiome

This review explores how maternal and early-life environmental exposures, including to emerging contaminants, can influence the development of the infant microbiome. Researchers found that factors such as nutrition, chemical exposures, and living conditions during pregnancy and early childhood shape the microbial communities that are critical for immune and metabolic development. The study highlights the importance of understanding how environmental pollutants may disrupt healthy microbiome establishment in vulnerable populations.

2022 Genome Medicine 68 citations
Article Tier 2

The Overview of the Possible Exposure of Infants to Microplastics

This review examines the various ways infants can be exposed to microplastics, including through breast milk, formula, baby food, plastic bottles, and toys. Researchers note that infants may be especially vulnerable because their metabolic and immune systems are still developing, potentially making them less able to process or eliminate these particles. The study calls for more research into infant-specific exposure levels and health effects, as current data remains limited.

2024 Preprints.org 6 citations
Article Tier 2

Current knowledge on the effects of environmental contaminants in early life nutrition

This review examines how environmental contaminants, including microplastics and endocrine-disrupting chemicals, can enter infant diets through breast milk, formula, and early solid foods. Researchers found that these pollutants transfer into breast milk through passive diffusion and can also leach from bottles, packaging, and food contact materials. The study emphasizes the need for better monitoring and regulation to protect infants during this critical developmental window.

2023 Frontiers in Nutrition 19 citations
Article Tier 2

Microplastics and child health: A scoping review of prenatal and early-life exposure routes and potential health risks

This scoping review examined how microplastics reach children through prenatal and early-life exposure routes, including placental transfer, breast milk, formula, and feeding bottles. The evidence indicates that microplastic exposure begins before birth and continues through infancy via multiple pathways, raising concerns about potential developmental health effects during these particularly vulnerable life stages.

2025 Toxicology Reports 1 citations
Systematic Review Tier 1

Health Implications of Microplastic Exposure in Pregnancy and Early Childhood: A Systematic Review

This systematic review summarizes existing research on how microplastic exposure during pregnancy and early childhood may affect health. The evidence shows that microplastics can reach the placenta and may cause oxidative stress and inflammation, raising concerns about potential effects on fetal development and infant health during these vulnerable life stages.

2025 International Journal of Women s Health 8 citations
Article Tier 2

An Overview of the Possible Exposure of Infants to Microplastics

This review summarizes the ways infants can be exposed to microplastics, including through the placenta before birth, breast milk, infant formula, plastic feeding bottles, and toys. Infants may face higher risks because their bodies are still developing and are less able to process and remove these particles. The authors call for more research and greater attention to reducing microplastic exposure in products designed for babies.

2024 Life 25 citations
Article Tier 2

What Health Concerns Could Micro and Nanoplastics Pose for Infants? A Review

Microplastics and nanoplastics have been detected in human placentas, meconium, and infant faeces, meaning babies can be exposed before and immediately after birth. This review examines what these early-life exposures might mean for infant health and development, and discusses broader policy responses to reduce plastic overproduction as the most direct route to protecting future generations.

2023 Preprints.org 1 citations
Article Tier 2

Marine Microplastics and Infant Health

This review examines the accumulation of marine microplastics and their potential implications for infant health, a uniquely vulnerable population. The authors discuss exposure pathways including breast milk and formula and highlight the need for targeted research on developmental health effects given the limited body of evidence in young children and infants.

2024 1 citations
Article Tier 2

Human Milk—The Biofluid That Nourishes Infants from the First Day of Life

This review highlights that human breast milk, while being the ideal nutrition for infants, is now subject to contamination by environmental pollutants including microplastics. The presence of microplastics in breast milk means that infants may be exposed to plastic particles from the very first days of life. The authors call for new monitoring methods to better understand the extent of contamination and its potential effects on infant development.

2024 Foods 10 citations
Article Tier 2

A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens

This review examines how humans are exposed to microplastics through air, dust, water, food, and even baby bottles, with estimated intake ranging from tens of thousands to millions of particles per year. Emerging evidence suggests that microplastics may act as obesogens, meaning they could disrupt fat metabolism and hormonal systems through chemical additives like phthalates and bisphenols. The review raises particular concern about infant exposure, as babies may face higher levels of microplastics from plastic feeding bottles and medical devices.

2021 Frontiers in Endocrinology 511 citations
Article Tier 2

Microplastic and human health with focus on pediatric well-being: a comprehensive review and call for future studies

This review focuses on how microplastics affect children specifically, from infancy through adolescence, finding that infant formula, plastic toys, food packaging, and contaminated water and air are all significant exposure sources. The particles can cause cell damage and have been linked to potential health risks including cancer, highlighting that children may be especially vulnerable because of their developing bodies and higher relative exposure.

2024 Clinical and Experimental Pediatrics 32 citations
Article Tier 2

Marine Microplastics and Infant Health

Analysis of 3 million births in coastal areas across 15 countries found that in-utero exposure to marine microplastics — measured by remote sensing — was significantly associated with adverse birth outcomes, providing the first empirical population-scale link between microplastic exposure and infant health.

2024 arXiv (Cornell University)
Article Tier 2

Detection of various microplastics in placentas, meconium, infant feces, breastmilk and infant formula: A pilot prospective study

In a pilot study of 18 mother-infant pairs, researchers detected microplastics in placentas, meconium (first stool), infant feces, breast milk, and infant formula. The finding of microplastics in breast milk and formula means that infants are exposed to microplastics from their earliest feedings, both natural and artificial. This study reveals that microplastic exposure begins before birth and continues through infancy, a critical period of development.

2022 The Science of The Total Environment 392 citations
Article Tier 2

Microplastic Exposure to Infants

This review summarizes current evidence on microplastic exposure in infants, covering detection in feces, breast milk, and infant formulas. The authors highlight that infants may face greater health risks from microplastic exposure than adults due to immature metabolic systems and higher sensitivity.

2024 1 citations
Article Tier 2

Micro problems with Macro Consequences: Accumulation of Persistent Organic Pollutants and Microplastics in Human Breast Milk and in Human Milk Substitutes

This review examines the co-occurrence of persistent organic pollutants (POPs) and microplastics in human breast milk and infant formula, highlighting that infants — one of the most vulnerable populations — may be exposed to both chemical and particle-based contaminants through feeding. The authors stress that the health effects of microplastic ingestion in early life remain largely unknown, making this a critical gap in understanding long-term developmental risks.

2023 2 citations
Article Tier 2

Hidden Threats in Infant Diets and Environment ‒ Risks of Microplastics and Nanoplastics in Food

This review examines how infants aged 0-12 months are exposed to microplastics and nanoplastics through inhalation and ingestion, with plastic packaging and food preparation being major dietary sources. Researchers found that these particles can cross biological barriers, leading to systemic exposure that may affect infant development. The study calls for more comprehensive research to understand the long-term health implications of plastic particle contamination in infant diets.

2025 Reviews of Environmental Contamination and Toxicology 1 citations
Article Tier 2

[Progress in research of effects of microplastic exposure on maternal and infant health].

This Chinese-language review summarizes microplastic research relevant to maternal and infant health, covering exposure pathways in pregnant women and offspring, epidemiological and toxicological evidence on health impacts, and proposed priorities for future research.

2025 PubMed
Article Tier 2

Placental microplastics contamination and its impact on thyroid function in newborns

Researchers analyzed placental tissue from over 1,200 mother-child pairs and found microplastics present in the samples, then examined whether these levels were associated with thyroid hormone profiles in the newborns. The study found associations between placental microplastic contamination and variations in newborn thyroid function, which is critical for early growth and development. These findings suggest that prenatal microplastic exposure warrants further investigation as a potential factor in infant health.

2025 Ecotoxicology and Environmental Safety 3 citations
Systematic Review Tier 1

Placental Micro- and Nanoplastic Contamination: A Systematic Review of Eco-Exposome Pathways to Preterm Birth and Neonatal Outcomes

This systematic review examined evidence that micro- and nanoplastics have been found in human placentas and may be linked to preterm birth. The particles appear to cause inflammation, oxidative stress, and disruption of placental function through multiple molecular pathways, raising concerns about the impact of plastic pollution on pregnancy outcomes and newborn health.

2025
Article Tier 2

Microplastics exposure during perinatal period: Impacts on neonatal immune and metabolic programming - a scoping review

This scoping review synthesizes research on microplastic exposure during the perinatal period and its potential impacts on neonatal immune and metabolic development. Researchers evaluated mechanisms of immune and metabolic disruption, size- and dose-dependent effects, and the exposure pathways that may influence newborn health outcomes. The study highlights that the developing fetus and newborn may be particularly vulnerable to micro- and nanoplastic exposure.

2026 Journal of Perinatology
Article Tier 2

Seafood Toxicant Exposure During Pregnancy, Lactation, and Childhood and Child Outcomes: A Scoping Review

Researchers conducted a scoping review of studies on toxicant exposure through seafood during pregnancy and childhood, finding that most research focuses on mercury while microplastics have received almost no study. This gap highlights the need for systematic research on how microplastic exposure through seafood affects fetal and child development.

2024 Advances in Nutrition 9 citations
Systematic Review Tier 1

Impact of Microplastics on Pregnancy and Fetal Development: A Systematic Review

A systematic review of 12 studies confirmed the presence of microplastics ranging from 2.1 to 100 micrometers in human placentas and fetal tissue. Microplastic levels correlated with reduced birthweight, affected gestational age, diminished microbiome diversity, and impaired fetal growth and development, with lifestyle choices influencing placental microplastic burden.

2024 Cureus 21 citations
Systematic Review Tier 1

Seafood Toxicant Exposure During Pregnancy, Lactation, and Childhood and Child Outcomes: A Scoping Review

This scoping review examines how toxins found in seafood, including contaminants that can accumulate on microplastics, affect child growth and development during pregnancy, breastfeeding, and early childhood. The review identified which toxin-outcome pairs have enough evidence for deeper analysis. The findings highlight the importance of understanding how environmental contaminants in our food supply may affect children's health.

2024 Current Developments in Nutrition