Papers

61,005 results
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Article Tier 2

Combined effect of microplastics and global warming factors on early growth and development of the sea urchin (Paracentrotus lividus)

Researchers studied the combined effects of microplastics, ocean acidification, and temperature increase on sea urchin larval development. Microplastics alone reduced larval growth by about 20%, but when combined with lowered pH, growth inhibition was significantly greater and morphological abnormalities appeared. The study demonstrates that microplastic pollution can compound the effects of climate change stressors on marine organisms during their most vulnerable developmental stages.

2021 The Science of The Total Environment 60 citations
Article Tier 2

Global climate change increases the impact of pollutant mixtures in the model species Paracentrotus lividus

Researchers found that ocean acidification and warming conditions predicted for the next 50 years significantly increased the toxicity of chlorpyrifos and microplastics on sea urchin fertilization and larval development, suggesting climate change will amplify the impact of pollutant mixtures on marine organisms.

2023 The Science of The Total Environment 8 citations
Article Tier 2

Developmental and biochemical markers of the impact of pollutant mixtures under the effect of Global Climate Change

Researchers studied how microplastics combined with the pesticide Chlorpyriphos affect sea urchin larvae under simulated ocean warming and acidification conditions. They found that the combination of these stressors caused significant developmental abnormalities and signs of oxidative stress in the larvae. The study suggests that the real-world cocktail of pollutants and climate change may be more harmful to marine life than any single stressor alone.

2024 Chemosphere 4 citations
Article Tier 2

Impact of microplastics and ocean acidification on critical stages of sea urchin (Paracentrotus lividus) early development

Researchers investigated the combined effects of microplastic pollution and ocean acidification on sea urchin early development, finding that acidified conditions amplified microplastic toxicity, disrupting fertilization, embryo development, and larval growth in Paracentrotus lividus.

2022 Chemosphere 24 citations
Article Tier 2

Effect of biodegradable polymers upon grazing activity of the sea urchin Paracentrotus lividus (Lmk) revealed by morphological, histological and molecular analyses

Researchers tested the effects of five types of biodegradable plastic microparticles on adult sea urchins, examining their reproductive tissues, embryo development, and gene expression. They found that exposure to these supposedly eco-friendly plastics caused developmental malformations in embryos and altered the expression of genes involved in stress response and skeletal development. The study raises concerns that biodegradable plastics may not be as harmless to marine organisms as often assumed.

2024 The Science of The Total Environment 9 citations
Article Tier 2

RNA sequencing provides insights into the effect of dietary ingestion of microplastics and cadmium in the sea cucumber Apostichopus japonicus

Researchers used RNA sequencing to examine combined microplastic and cadmium exposure effects on sea cucumbers, finding that co-exposure caused the most significant gene expression changes and oxidative stress responses, with 1,618 differentially expressed genes identified.

2023 Frontiers in Marine Science 9 citations
Article Tier 2

Polymer aging affects the bioavailability of microplastics-associated contaminants in sea urchin embryos

Researchers found that UV aging of microplastics alters the bioavailability of co-contaminants like flame retardants and metals to sea urchin embryos, with combined exposures generating transcriptional responses distinct from single-contaminant effects.

2022 Chemosphere 22 citations
Article Tier 2

Oysters under anthropogenic pressure: A cellular perspective on the interactive effects of microplastic pollution and climate change

Researchers exposed oysters to microplastics under combined conditions of elevated temperature and ocean acidification, finding that climate change stressors significantly altered the cellular response to MP pollution. Temperature had a stronger effect than acidification, and combined stressors produced non-additive interactions in immune and oxidative stress markers.

2025 Media (https://www.suub.uni-bremen.de/)
Article Tier 2

Molecular responses to pollution stress in glass eels (Anguilla anguilla): Gene expression changes associated with varying contamination levels and temperature across estuaries

Researchers measured gene expression in European eel glass eels entering estuaries with varying levels of microplastic and heavy metal contamination, finding that pollution and temperature shifts alter stress-response and metabolic gene expression in ways that may impair survival.

2025 Aquatic Toxicology
Article Tier 2

Linking biochemical and individual-level effects of chlorpyrifos, triphenyl phosphate, and bisphenol A on sea urchin (Paracentrotus lividus) larvae

Researchers examined the effects of chlorpyrifos, triphenyl phosphate, and bisphenol A on sea urchin larval development, linking biochemical biomarker responses like antioxidant enzyme changes to observable developmental abnormalities at the individual level.

2022 Environmental Science and Pollution Research 20 citations
Article Tier 2

Commercial product-derived microplastics based on polypropylene and polylactic acid and their harmful effects on the sea urchin Paracentrotus lividus (Lmk) embryos: Morphological and gene expression analysis

Researchers examined the toxic effects of polypropylene and polylactic acid microplastics derived from commercial products on embryos of the sea urchin Paracentrotus lividus, assessing morphological changes and gene expression. They found that both polymer types caused developmental harm, with plastic additives and degradation byproducts contributing to the toxic effects observed.

2025 Water Biology and Security
Article Tier 2

Effects of biodegradable-based microplastics in Paracentrotus lividus Lmk embryos: Morphological and gene expression analysis

Researchers tested the effects of biodegradable microplastics (PLA and PBAT) on sea urchin embryo development and found they caused developmental abnormalities and altered gene expression. Even though these plastics are marketed as eco-friendly alternatives, their breakdown particles still harmed marine organisms during sensitive early life stages. This suggests that biodegradable plastics are not necessarily safe for the environment and may still contribute to microplastic toxicity in the food chain.

2023 Environmental Pollution 35 citations
Article Tier 2

PVC pellet leachates affect adult immune system and embryonic development but not reproductive capacity in the sea urchin Paracentrotus lividus

Researchers investigated the effects of PVC plastic pellet leachates on adult sea urchins and their offspring. The study found that while adults in contaminated water still produced viable embryos, they showed reduced immune cell counts, increased oxidative stress, and produced offspring that were less tolerant of polluted environments, suggesting that sublethal plastic pollution effects in adults may carry over to reduce developmental resilience in future generations.

2023 Marine Pollution Bulletin 11 citations
Article Tier 2

Microplastic ingestion and its effects οn sea urchin Paracentrotus lividus: A field study in a coastal East Mediterranean environment

Researchers collected wild sea urchins from three coastal sites in the Ionian Sea with different levels of human activity and examined them for microplastic ingestion and biological stress markers. They found microplastics in sea urchins at all sites, with patterns matching sediment contamination, but most biomarkers showed no significant stress response. The exception was increased detoxification enzyme activity, suggesting the animals may be mounting a subtle biological response to ingested microplastics.

2023 Marine Pollution Bulletin 15 citations
Article Tier 2

Transcriptomic analysis of oxidative stress mechanisms induced by acute nanoplastic exposure in Sepia esculenta larvae

Researchers used transcriptomic analysis to reveal that acute nanoplastic exposure in cuttlefish larvae triggered oxidative stress through disruption of antioxidant enzyme gene expression, identifying key molecular pathways affected by plastic pollution in marine cephalopods.

2023 Frontiers in Physiology 10 citations
Article Tier 2

Molecular mechanisms controlling physiological plasticity in marine mussels under the influence of natural and anthropogenic stress factors

This thesis project investigated the molecular mechanisms that help Mediterranean mussels cope with environmental stress, including both natural factors and emerging pollutants like microplastics. Understanding these stress responses could help predict how marine shellfish will fare as pollution and climate change intensify.

2021
Article Tier 2

Exposure to global change and microplastics elicits an immune response in an endangered coral

Researchers examined how the combination of ocean warming, acidification, and microplastic exposure affects the endangered coral Acropora cervicornis over 22 days. They found that while individual stressors produced subtle gene expression changes, the combined multistressor treatment triggered the strongest response, particularly in genes related to innate immunity. The study suggests that microplastics may compound the effects of climate change on coral health by activating immune stress responses.

2023 Frontiers in Marine Science 26 citations
Article Tier 2

Beyond Single Stressors: Integrated Physiological and Transcriptomic Responses of Argopecten irradians Exposed to Polystyrene and Toxic Dinoflagellates

Researchers exposed bay scallops to polystyrene microplastics and toxic algae both individually and in combination, finding that while survival remained above 90%, the combined exposure triggered elevated oxidative stress markers and more complex physiological disruption. Transcriptomic analysis revealed that microplastics primarily interfered with endocrine function while the toxic algae affected immune pathways, and co-exposure produced synergistic effects on metabolism and developmental regulation.

2026 Oceans
Article Tier 2

Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics

The combined effects of diarrhetic shellfish toxin and microplastics on the mussel Mytilus coruscus were assessed at physiological and transcriptomic levels, revealing synergistic disruption of immune function, antioxidant responses, and metabolic pathways. The study provides molecular-level evidence of interactive toxicity between two common coastal contaminants.

2022 Frontiers in Marine Science 18 citations
Article Tier 2

Uptake and transcriptional effects of polystyrene microplastics in larval stages of the Mediterranean mussel Mytilus galloprovincialis

Researchers exposed larval stages of a marine organism to polystyrene microplastics and measured gene expression changes, finding tissue-dependent transcriptional responses that suggest microplastics can affect development even at early life stages.

2018 Environmental Pollution 142 citations
Article Tier 2

Unraveling the interplay between environmental microplastics and salinity stress on Mytilus galloprovincialis larval development: A holistic exploration

Researchers studied how environmental microplastics and increased salinity together affect the early development of Mediterranean mussel larvae. The combination caused larval deformities, developmental problems, and changes in gene activity related to shell formation, stress response, and cell damage. These findings are concerning because climate change is altering ocean salinity in coastal areas where microplastic pollution is also heavy, and mussels are a food source that could pass accumulated microplastics to humans.

2024 The Science of The Total Environment 13 citations
Article Tier 2

Vanadium Toxicity Is Altered by Global Warming Conditions in Sea Urchin Embryos: Metal Bioaccumulation, Cell Stress Response and Apoptosis

Researchers studied how vanadium, an emerging metal pollutant, affects sea urchin embryo development under warmer ocean temperatures. They found that elevated temperatures altered how vanadium accumulates in embryos and intensified cellular stress responses and programmed cell death. The study suggests that climate change and metal pollution together may pose a greater threat to marine life than either stressor alone.

2024 Journal of Xenobiotics 6 citations
Article Tier 2

Embryotoxicity of polystyrene microplastics, alone and conjugated with bisphenol A, in the black sea urchin Arbacia lixula: A multi-biomarker approach

Researchers tested the effects of polystyrene microplastics and the chemical bisphenol A, both alone and combined, on sea urchin embryo development. While bisphenol A caused severe skeletal abnormalities and developmental arrest, its toxicity was actually reduced when attached to microplastic surfaces rather than amplified. The study found no synergistic toxic effect between the two pollutants under acute exposure conditions, though both individually disrupted metabolic and oxidative stress pathways.

2025 Journal of Hazardous Materials 4 citations
Article Tier 2

Indication of the impact of environmental stress on the responses of the bivalve mollusk Unio tumidus to ibuprofen and microplastics based on biomarkers of reductive stress and apoptosis

Researchers compared freshwater mussels from clean and contaminated sites exposed to microplastics and ibuprofen, finding that chronically stressed populations showed altered biomarker responses for reductive stress and apoptosis, highlighting how environmental history modulates pollutant sensitivity.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 25 citations