Papers

20 results
|
Article Tier 2

Synthetic microfiber exposure negatively affects reproductive parameters in male medaka (Oryzias latipes)

Researchers exposed male medaka fish to fiber-type microplastics and found disruptions to the hormonal pathway that regulates reproduction. The microfibers triggered abnormal expression of reproductive hormones and induced vitellogenesis, a process normally occurring only in females, indicating endocrine disruption. The study suggests that microfiber ingestion may impair reproductive capacity in fish by interfering with hormonal signaling.

2023 General and Comparative Endocrinology 23 citations
Article Tier 2

Developmental Polyethylene Microplastic Fiber Exposure Entails Subtle Reproductive Impacts in Juvenile Japanese Medaka (Oryzias latipes)

Japanese medaka fish exposed to environmentally relevant levels of polyethylene microplastic fibers throughout development showed subtle but measurable reproductive impacts including alterations in gonadal development. The findings suggest that chronic low-dose microplastic fiber exposure during early life may impair future reproductive capacity in fish.

2022 Environmental Toxicology and Chemistry 18 citations
Article Tier 2

Polystyrene microplastics disrupt female reproductive health and fertility via sirt1 modulation in zebrafish (Danio rerio)

This study found that polystyrene microplastics disrupted female reproductive health in zebrafish by interfering with a key protein called SIRT1 that regulates hormone production. Exposed fish showed changes in egg development, hormone levels, and ovarian tissue structure. Since the hormonal pathways affected are similar in humans, these findings raise concerns about how microplastic exposure might contribute to fertility problems in women.

2023 Journal of Hazardous Materials 85 citations
Article Tier 2

Behavioral Studies of Zebrafish Reveal a New Perspective on the Reproductive Toxicity of Micro- and Nanoplastics

This review summarizes existing research on how micro- and nanoplastics affect the behavior and reproductive health of zebrafish, a common lab model for studying human biology. The findings suggest that tiny plastic particles can disrupt reproductive behavior and act as hormone-like chemicals, and that behavioral changes in fish may serve as early warning signs of reproductive harm that could be relevant to understanding human health risks.

2024 Toxics 34 citations
Article Tier 2

Polyester Microfiber Accumulation and Toxicological Effects on Freshwater Fish Labeo rohita.

Scientists found that tiny plastic fibers from polyester clothing seriously harm freshwater fish when they eat them, causing stress, behavioral changes like increased aggression, and disrupting their body chemistry. This matters because these same plastic fibers are widespread in our water systems and food chain, potentially affecting the fish we eat and the water we drink. The study shows we need to reduce plastic pollution from synthetic clothing to protect both aquatic life and human health.

2026 Environmental toxicology and pharmacology
Article Tier 2

Effects of microplastic exposure on the gonadal structure and reproductive success of Danio rerio (Teleostei: Cypriniformes)

This Brazilian study exposed zebrafish to two concentrations of microplastics for 30 days and assessed effects on gonadal structure and reproductive success using histology and hormone assays. Microplastic exposure disrupted reproductive biology in both males and females, raising concerns about how environmental microplastic contamination affects fish reproduction.

2021 LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Article Tier 2

Polystyrene microplastics-induced gut microbiota dysbiosis with altered short chain fatty acid is associated with reproductive physiology and endocrine disorder in female zebrafish

Researchers found that polystyrene microplastics disrupted gut bacteria in female zebrafish, leading to inflammation, hormone imbalances, and impaired egg development. The study provides the first evidence that microplastic-induced gut microbiome changes can drive reproductive problems through a chain reaction involving immune, metabolic, and hormonal pathways.

2025 Journal of Hazardous Materials 2 citations
Article Tier 2

Polystyrene Nanoplastics Disrupt Hepatic Vitellogenin Metabolism and Impair the Reproduction Process in Female Zebrafish

Researchers exposed female zebrafish to polystyrene nanoplastics and found that the particles disrupted the production of vitellogenin, a key protein involved in egg development. Higher concentrations led to reduced reproductive output and changes in liver function. The study suggests that nanoplastic pollution in waterways could interfere with fish reproduction by disrupting the hormonal and metabolic pathways essential for egg formation.

2024 Annals of Animal Science 9 citations
Article Tier 2

Some Behavioural and Physiological Effects of Plastics (Polyethylene) on Fish

Researchers examined behavioral and physiological effects of polyethylene microplastics on fish, finding that plastic exposure disrupted endocrine function, altered behavior, and impaired normal development and reproduction.

2023 Tropical Aquatic and Soil Pollution 10 citations
Article Tier 2

Evaluating the potential of daily intake of polystyrene microplastics via drinking water in inducing PCOS and its ovarian fibrosis progression using female zebrafish

Daily exposure to polystyrene microplastics through drinking water caused symptoms of polycystic ovary syndrome (PCOS) in female zebrafish, including hormone imbalances, cystic ovaries, and insulin resistance. Over time, the affected ovaries also developed signs of fibrosis, or scarring. This study suggests that microplastics in drinking water could be a contributing factor to reproductive disorders and long-term ovarian damage.

2024 NanoImpact 21 citations
Article Tier 2

Chronic microfiber exposure in adult Japanese medaka (Oryzias latipes)

Adult Japanese medaka fish chronically exposed to polyester and polypropylene microfibers showed histological changes in gut and liver, altered gene expression in inflammation and oxidative stress pathways, and disrupted reproductive output, demonstrating tissue-level harm from realistic fiber concentrations.

2020 PLoS ONE 105 citations
Article Tier 2

Realistic microplastics harness bacterial presence and promote impairments in early zebrafish embryos: Behavioral, developmental, and transcriptomic approaches.

Researchers exposed zebrafish embryos to realistic microplastic fragments and fibers from bottles and textiles, both alone and combined with a bacterial pathogen. They found that microplastics adhered to egg surfaces and accelerated hatching, while fragments were more harmful to development than fibers. The study provides new insights into how microplastics interact with environmental pathogens to affect early life stages of aquatic organisms.

2024 Chemosphere 13 citations
Article Tier 2

Ingestion and effects of virgin polyamide microplastics on Chironomus riparius adult larvae and adult zebrafish Danio rerio

Scientists fed polyamide microplastics to Chironomus riparius larvae and adult zebrafish, finding ingestion in both species, with larger particles retained in fish intestines and both species showing signs of inflammation and oxidative stress.

2020 Chemosphere 68 citations
Article Tier 2

Microplastics induced endocrine disruption, alteration in testicular tissue in tilapia (Oreochromis niloticus) pre-fed on Amphora coffeaeformis

Researchers found that microplastic exposure caused hormonal disruption, reduced sperm quality, and damaged testicular tissue in male tilapia fish, but pre-feeding the fish with a microalgae feed supplement partially protected against these reproductive harms. The study suggests that dietary interventions may help mitigate microplastic toxicity in fish farmed for human consumption.

2021 3 citations
Article Tier 2

Environmental microplastics accumulate in gonads in a sex-dependent manner and alter reproductive success in zebrafish (Danio rerio)

Zebrafish exposed to environmentally sourced microplastics accumulated particles preferentially in the testes rather than ovaries, and males showed the highest gonadal microplastic loads along with PCB co-contaminant effects including inhibited apoptosis and hepatotoxicity.

2025 Journal of Hazardous Materials Advances
Article Tier 2

Microplastics Lead to Hyperactive Swimming Behaviour in Adult Zebrafish

Researchers exposed adult zebrafish to polystyrene microplastics across a wide concentration range and found that microplastics accumulated primarily in the gastrointestinal tract and gills. The study revealed that exposed fish exhibited hyperactive swimming behavior, suggesting that microplastic ingestion can affect locomotor activity even without obvious physical damage to internal organs.

2020 Aquatic Toxicology 178 citations
Article Tier 2

Chronic Exposure of Adult Zebrafish to Polyethylene and Polyester-based Microplastics: Metabolomic and Gut Microbiome Alterations Reflecting Dysbiosis and Resilience

Researchers exposed adult zebrafish to polyethylene and polyester microplastics at environmentally relevant concentrations and found significant disruptions to metabolic pathways and gut microbiome composition. Polyethylene primarily affected cell membrane compounds and inflammation-related metabolites, while polyester altered lipid metabolism and gut bacterial interactions. The study reveals that chronic microplastic exposure can cause subtle but meaningful shifts in fish metabolism and gut health, even at low concentrations.

2024 Journal of Hazardous Materials 9 citations
Article Tier 2

Female zebrafish (Danio rerio) exposure to polystyrene nanoplastics induces reproductive toxicity in mother and their offspring

Researchers exposed female zebrafish to polystyrene nanoplastics for six weeks and found the particles disrupted sex hormone levels and oocyte development, reducing egg production in the exposed generation and carrying endocrine disruption effects into unexposed offspring through the hypothalamic-pituitary-gonadal axis.

2024 Aquatic Toxicology 21 citations
Article Tier 2

Microplastics stunt fish growth and alter behavior

A study of European perch larvae found that high levels of polystyrene microplastics inhibited hatching, stunted growth, and made fish more likely to be eaten by predators. These findings raised serious concern about microplastic impacts on fish populations and the marine food supply that humans depend on.

2016 C&EN Global Enterprise
Article Tier 2

Effects of pristine or contaminated polyethylene microplastics on zebrafish development

Researchers examined the effects of both pristine and pollutant-contaminated polyethylene microplastics on zebrafish development through chronic exposure. The study assessed how microplastics, both alone and as carriers of adsorbed organic pollutants, affect developing fish. The findings provide new insights into how contaminated microplastics may create additional routes for toxic compounds to enter aquatic food webs.

2022 Chemosphere 66 citations