Papers

61,005 results
|
Article Tier 2

Exposure and inhaling of microplastics: An evidence of cause of cancer

This review examined the evidence linking microplastic inhalation to cancer risk, covering how inhaled MPs accumulate in the lungs, trigger chronic inflammation, oxidative stress, and DNA damage, and may contribute to lung carcinogenesis. The authors identified microplastic inhalation as an underappreciated occupational and environmental cancer risk.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Exposure and inhaling of microplastics: An evidence of cause of cancer

This review examined microplastic inhalation as a potential cause of cancer, surveying pathways by which inhaled MP particles accumulate in lung tissue and drive oncogenic processes through inflammation, oxidative damage, and DNA strand breaks. The evidence reviewed supports classifying microplastic inhalation as an emerging environmental cancer risk factor.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Plastic pollution-Microplastics: Cancer related issues

This review examines how microplastics may contribute to cancer risk, summarizing evidence that ingested microplastics can cross the gut epithelium, accumulate in tissues, induce oxidative stress and inflammation, and carry carcinogenic chemical additives.

2025 World Journal of Biology Pharmacy and Health Sciences
Article Tier 2

Microplastics as emerging carcinogens: from environmental pollutants to oncogenic drivers

This review examines growing evidence that microplastics and nanoplastics may play a role in cancer development, with these particles found in human tumor tissues from the lungs, colon, stomach, breast, and other organs. The particles appear to promote cancer through chronic inflammation, oxidative stress, DNA damage, and disruption of key cancer-related signaling pathways. While direct proof of causation in humans is still lacking, the accumulating evidence from lab studies, animal experiments, and human tissue analysis suggests microplastics deserve serious attention as potential contributors to cancer risk.

2025 Molecular Cancer 7 citations
Systematic Review Tier 1

From Exposure to Oncogenesis: the Role of Microplastics and Associated Pollutants in Cancer - a Literature Review

This literature review examined the growing evidence linking microplastic exposure to cancer development. Microplastics have been found in human lung, liver, and colon tissue, and research suggests they may promote cancer through chronic inflammation, oxidative stress, and by carrying known carcinogens like heavy metals and persistent organic pollutants into the body.

2025 International Journal of Innovative Technologies in Social Science
Article Tier 2

The impact of environmental microplastics as emerging carcinogens: A public health concern

This review investigated the mechanisms by which microplastics may contribute to cancer development, examining studies from 2010 to 2024. Researchers found that microplastics can induce oxidative stress, inflammation, and DNA damage through multiple pathways, and that human exposure occurs primarily through ingestion, inhalation, and dermal contact. The study suggests that microplastics represent an emerging class of environmental concern warranting further investigation into their long-term health effects.

2024 Multidisciplinary Reviews 2 citations
Article Tier 2

Microplastics and cancer

This review examines evidence linking microplastics to cancer risk, noting that microplastics have been detected at higher concentrations in human tumor tissues than adjacent healthy tissue, and that they can act as vectors for carcinogens while inducing oxidative stress, inflammation, and genotoxicity.

2025 European Journal of Cancer Prevention
Article Tier 2

The Relationship Between Microplastics and Nanoplastics with Cancer: An Emerging Health Concern

This review explores the emerging relationship between micro- and nanoplastic exposure and cancer risk in humans. Researchers summarized evidence suggesting that microplastics can carry carcinogenic substances and may trigger inflammatory and oxidative stress pathways linked to tumor development. The study highlights that while early evidence raises concern, more research is needed to establish clear causal connections between plastic particle exposure and specific cancer types.

2024 International Journal of Hematology and Oncology 3 citations
Article Tier 2

Microplastics and Cancer: A Comprehensive Review of Their Impact on Tumor Progression and Mechanisms of Carcinogenesis

This comprehensive review examines the growing body of evidence linking microplastic exposure to various types of cancer, including colorectal, lung, liver, and breast cancers. Researchers found that microplastics and nanoplastics may promote tumor progression through mechanisms including oxidative stress, chronic inflammation, and disruption of cellular signaling pathways. While the evidence is still emerging, the study highlights the need for further research into the potential cancer-related risks of widespread microplastic exposure.

2025 Journal of Environmental Pathology Toxicology and Oncology 2 citations
Article Tier 2

The hidden poison - microplastic : Inflammatory catalyst of cancer development

This review discusses how microplastics act as inflammatory agents within biological tissues, summarizing evidence that ingested and inhaled microplastics can trigger oxidative stress, immune responses, and chronic inflammation in humans and animals.

2024 INTERNATIONAL JOURNAL PLANT SCIENCES
Review Tier 2

Microplastics Exposure Impact on Lung Cancer—Literature Review

This review examines the relationship between micro- and nanoplastic exposure and lung cancer development, summarizing evidence that these particles can enter the respiratory system through inhaled air, contaminated food, and other pathways. Researchers found that microplastics may promote inflammatory and oxidative processes in lung tissue that are associated with cancer progression. The study suggests that chronic microplastic exposure warrants consideration as a potential contributing factor in lung cancer research.

2025 Cancers 1 citations
Article Tier 2

Microscopic menace: exploring the link between microplastics and cancer pathogenesis

This review examines the growing evidence linking microplastic exposure to cancer development in humans. Microplastics can accumulate in the body and trigger inflammation, oxidative stress, and other biological changes associated with tumor growth. While more clinical research is needed, the review highlights that microplastics should be taken seriously as a potential factor in cancer risk.

2025 Environmental Science Processes & Impacts 8 citations
Article Tier 2

Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans?

This review examines how microplastics and nanoplastics enter the human body through food, water, and air, and how they may contribute to cancer development. Common plastic types like polystyrene and PVC, along with toxic chemicals they carry such as PAHs and PCBs, have been linked to DNA damage, oxidative stress, and inflammation, all of which can promote cancer. The paper highlights that while the evidence is growing, more research is needed to understand the full cancer risk from chronic microplastic exposure.

2022 Chemosphere 367 citations
Article Tier 2

From exposure to oncogenesis: a review on the multifaceted roles of microplastics in tumor initiation and progression

This review examined the evidence linking microplastic exposure to tumor initiation and progression, covering physical, chemical, and inflammatory mechanisms by which MPs may promote oncogenesis. The authors conclude that while current evidence is largely preclinical, accumulating data warrant serious concern about microplastics as environmental carcinogens.

2025 Journal of Translational Medicine
Article Tier 2

Evaluating the relationship between microplastics and nanoplastics contamination and diverse cancer types development

This review examines growing evidence that micro- and nanoplastics found in human tissues may contribute to cancer development through several pathways. These tiny particles can generate harmful molecules called reactive oxygen species, cause chronic inflammation, and disrupt cell growth signals, all of which are known to promote cancer. While long-term, high-level exposure likely poses the greatest risk, more research is needed to understand the full cancer-related dangers of microplastic exposure.

2025 Environmental Pollution 6 citations
Article Tier 2

The hidden threat: Microplastics and cancer biology

This review synthesizes current research on the potential links between micro- and nanoplastic exposure and cancer biology, examining how these particles may contribute to tumor development in organs including the gut, lungs, skin, liver, kidney, and brain. The study suggests that chronic exposure to plastic particles can trigger molecular changes such as oxidative stress, inflammation, and DNA damage that are associated with cancer initiation, though clear causal evidence in humans is still lacking.

2026 Journal of Hazardous Materials
Article Tier 2

The alarming link between environmental microplastics and health hazards with special emphasis on cancer

This review describes how microplastics enter the human body through the nose, skin, and mouth, then penetrate cells where they can alter gene expression, fuel inflammation, disrupt hormone signaling, and promote uncontrolled cell growth. Studies have linked microplastic exposure to cancers of the lungs, blood, breast, prostate, and ovaries, though the precise molecular mechanisms still need further investigation.

2024 Life Sciences 90 citations
Article Tier 2

Insights into the potential carcinogenicity of micro- and nano-plastics.

This review examined existing evidence on the carcinogenic potential of micro- and nano-plastics, finding studies demonstrating genotoxicity, oxidative DNA damage, disruption of cell signaling, and tumor-promoting effects, while noting that direct human carcinogenicity data remain limited and mechanistic pathways require further investigation.

2023 Mutation research. Reviews in mutation research
Article Tier 2

Microplastics – A Growing Concern as Carcinogens in Cancer Etiology: Emphasis on Biochemical and Molecular Mechanisms

This review describes how microplastics smaller than 5 mm can enter human cells and promote cancer development through multiple pathways, including DNA damage, oxidative stress, chronic inflammation, and disruption of cell growth controls. Microplastics also carry other contaminants into the body, and their accumulation in tissues raises concerns about long-term cancer risk, particularly in the lungs, skin, and digestive system.

2024 Cell Biochemistry and Biophysics 43 citations
Article Tier 2

Respiratory Toxicity of Microplastics: Mechanisms, Clinical Outcomes, and Future Threats

This review examined the mechanisms by which inhaled airborne microplastics cause respiratory harm, including inflammation, oxidative stress, fibrosis, and impaired mucociliary clearance. The authors also discuss emerging evidence linking microplastic inhalation to worsening asthma, COPD, and potentially lung cancer.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Do microplastics (MPs) and nanoplastics (NPs) directly contribute to human carcinogenesis?

This review examines whether microplastics and nanoplastics could directly contribute to cancer development in humans. Evidence from lab and animal studies shows these particles can cause DNA damage, chronic inflammation, oxidative stress, and disrupt important cancer-related signaling pathways. While a direct causal link to human cancer has not been proven yet, the review argues that microplastics should be considered potential cancer-promoting agents that warrant urgent further research.

2025 Environmental Pollution 7 citations
Article Tier 2

Molecular mechanisms of air pollution–induced carcinogenesis and the emerging role of microplastics

This review examined the molecular mechanisms by which air pollution components — including fine particulate matter, microplastics, volatile organic compounds, and heavy metals — contribute to cancer development. The authors identify microplastics as an emerging air pollution carcinogen that can carry and deliver chemical carcinogens into lung tissue.

2025 Human Genomics
Article Tier 2

Potential health impact of environmental micro‐ and nanoplastics pollution

This review examines the potential health impacts of micro- and nanoplastic pollution on humans, focusing on oral and inhalation exposure routes. The study discusses how the potential toxicity of plastic particles arises from the plastics themselves, leachable chemical additives, and adsorbed environmental contaminants. Evidence indicates that the primary health concerns involve gastrointestinal and liver effects, with oxidative stress, inflammation, and metabolism disruption as key toxicological mechanisms.

2019 Journal of Applied Toxicology 312 citations
Article Tier 2

Microplastics in Early Onset Carcinogenesis

This review examines the emerging hypothesis that chronic microplastic exposure may contribute to cancer risk, noting that these particles provoke oxidative stress, inflammation, DNA damage, and microbiome disruption. Researchers highlight a temporal overlap between rising plastic production since the 1950s and increasing rates of early-onset cancers, though a causal link has not been established. The study suggests that lifelong microplastic exposure beginning in utero warrants further investigation as a potential contributing factor.

2026 Carcinogenesis