Papers

61,005 results
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Article Tier 2

Individual and Collective Effect of Lactic Acid Bacteria on Staphylococcus aureus

Researchers tested whether lactic acid bacteria probiotic strains could inhibit the growth of the foodborne pathogen Staphylococcus aureus. The probiotic combination was more effective than individual strains, with potential applications in food safety. This type of research is relevant to gut health contexts where microplastic exposure may disrupt the protective microbiome.

2023 Journal of Bacteriology & Mycology Open Access
Article Tier 2

Deciphering Microbiome, Transcriptome, and Metabolic Interactions in the Presence of Probiotic Lactobacillus acidophilus against Salmonella Typhimurium in a Murine Model

Researchers tested whether the probiotic Lactobacillus acidophilus could protect mice against Salmonella Typhimurium infection by examining changes in gut bacteria, gene expression, and metabolic pathways. They found that probiotic treatment improved gut microbial balance, reduced harmful bacterial load, and modulated immune and metabolic responses. The study suggests that probiotics may offer a promising alternative strategy to antibiotics for managing certain foodborne bacterial infections.

2024 Antibiotics 7 citations
Article Tier 2

Lactobacillus plantarum A3 attenuates ulcerative colitis by modulating gut microbiota and metabolism

Researchers showed that Lactobacillus plantarum A3, a probiotic strain isolated from horses, reduced symptoms of ulcerative colitis in mice whose gut microbiomes had been disrupted by antibiotics. The probiotic restored beneficial bacteria like Akkermansia, reduced gut inflammation, and increased levels of natural anti-inflammatory compounds in the body.

2023 Animal Diseases 22 citations
Article Tier 2

Lactic acid bacteria reduce polystyrene micro- and nanoplastics-induced toxicity through their bio-binding capacity and gut environment repair ability

Researchers found that lactic acid bacteria, the kind used in yogurt and fermented foods, can reduce the toxic effects of polystyrene micro and nanoplastics in mice. The bacteria worked by physically binding to the plastic particles and by repairing damage to the gut lining and restoring healthy gut bacteria populations. This suggests that probiotics could be a practical way to help protect the digestive system from the harmful effects of microplastic exposure through food and water.

2024 Environmental Pollution 10 citations
Article Tier 2

Effects of repeated intragastric administrations with heat-inactivated Mycobacterium aurum DSM 33539 on the stress-induced aggravation of dextran sulfate sodium (DSS) colitis in C57BL/6N mice

Researchers tested whether a heat-inactivated preparation of the soil bacterium Mycobacterium aurum could protect mice from stress-aggravated intestinal inflammation. They found that oral administration of M. aurum reduced the severity of stress-induced colitis and helped maintain intestinal barrier integrity. The study suggests that certain beneficial environmental bacteria may help protect gut health under stressful conditions, though more research is needed.

2025 Frontiers in Neuroscience 2 citations
Article Tier 2

Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics in mice

Researchers found that the probiotic Lactobacillus rhamnosus GG helped protect mice from liver damage caused by polystyrene microplastic exposure. The probiotic worked by restoring healthy gut bacteria and normalizing liver metabolic pathways disrupted by the microplastics. The study suggests that supporting gut health through beneficial bacteria may help mitigate some of the toxic effects microplastics have on the liver.

2023 Environmental Science and Pollution Research 25 citations
Article Tier 2

A probiotic for preventing microplastic toxicity: Clostridium dalinum mitigates microplastic-induced damage via microbiota-metabolism-barrier interactions

Using metagenomics and metabolomics, this study found that the probiotic bacterium Clostridium dalinum reduced microplastic-induced gut damage in mice by modulating gut microbiota composition, metabolic pathways, and intestinal barrier integrity.

2025 Current Research in Food Science
Article Tier 2

A Single Strain of Lactobacillus (CGMCC 21661) Exhibits Stable Glucose- and Lipid-Lowering Effects by Regulating Gut Microbiota

Researchers identified a novel Lactobacillus strain (CGMCC 21661) that outperformed fecal microbiota transplantation and Bifidobacterium in lowering blood glucose and lipids in diabetic mice, demonstrating stable therapeutic effects through gut microbiota regulation.

2023 Nutrients 8 citations
Article Tier 2

A Lactobacilli diet that confers MRSA resistance causes amino acid depletion and increased antioxidant levels in the C. elegans host

A Lactobacillus diet in C. elegans worms produced resistance to MRSA infection by depleting certain amino acids and increasing antioxidant levels in the host. The study shows that probiotic bacteria can protect against pathogenic bacteria through metabolic changes rather than direct competition. These findings support further research into probiotics as alternatives to traditional antibiotics.

2022 Frontiers in Microbiology 7 citations
Article Tier 2

The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota -liver-brain axis

Researchers tested whether the probiotic supplement SLAB51 could counteract the harmful effects of bisphenol A (BPA), a plastic-derived chemical, in zebrafish and found it significantly restored healthy gut bacteria, reduced liver damage, and protected the brain — suggesting probiotics may help offset harm from plastic-associated chemical exposure.

2023 The Science of The Total Environment 21 citations
Article Tier 2

Bioactive compound and chemical characterization of lactic acid bacteria from fermented food as bio-preservative agents to control food-borne pathogens

Thai researchers screened lactic acid bacteria from fermented foods and identified four Lactobacillus species with antibacterial activity against common food pathogens including E. coli and Staphylococcus aureus. The best-performing strain showed promising properties for use as a natural food preservative.

2023 Journal of Pharmacy & Pharmacognosy Research 2 citations
Article Tier 2

Lactobacillus plantarum reduces polystyrene microplastic induced toxicity via multiple pathways: A potentially effective and safe dietary strategy to counteract microplastic harm

Researchers found that Lactobacillus plantarum, a probiotic bacterium commonly found in fermented foods, can reduce the harmful effects of polystyrene microplastics in mice through multiple pathways. The bacteria worked by binding directly to plastic particles to help remove them from the body, reducing oxidative damage, repairing the intestinal barrier, and regulating bile acid metabolism. This suggests that certain probiotics could be a safe dietary strategy to help counteract some of the negative health effects of microplastic exposure.

2025 Journal of Hazardous Materials 6 citations
Article Tier 2

Prevention of Loperamide-Induced Constipation in Mice and Alteration of 5-Hydroxytryotamine Signaling by Ligilactobacillus salivarius Li01

Researchers found that the probiotic Ligilactobacillus salivarius Li01 alleviates constipation in mice by modulating the serotonin signaling pathway, improving intestinal barrier function, and altering gut microbiota composition.

2022 Nutrients 38 citations
Meta Analysis Tier 1

The impact of microplastics on the mice gut microbiome: a meta-analysis

This meta-analysis pools data from multiple mouse studies to assess how ingested microplastics affect gut bacteria. It found that microplastic exposure can alter the balance of the gut microbiome, which is important because gut health is closely tied to immune function, digestion, and overall well-being.

2025
Systematic Review Tier 1

Probiotics as Modulators of Microplastic-induced Toxicity: A Systematic Review

This systematic review found that probiotics can reduce microplastic-induced toxicity in animal models by restoring gut microbiota balance, reducing oxidative stress, and modulating inflammatory responses. The findings suggest that probiotic supplementation may help mitigate the harmful effects of unavoidable microplastic exposure, though human clinical trials are still needed.

2025 Probiotics and Antimicrobial Proteins
Article Tier 2

Lactiplantibacillus plantarum P101 Alleviates Liver Toxicity of Combined Microplastics and Di-(2-Ethylhexyl) Phthalate via Regulating Gut Microbiota

Researchers found that the probiotic Lactiplantibacillus plantarum P101 reduced liver damage caused by combined exposure to microplastics and the plasticizer DEHP in mice. The probiotic reversed oxidative stress and inflammation in the liver and intestines while reshaping the gut microbiota. The study suggests that probiotic supplementation may offer a promising strategy for mitigating the toxic effects of co-exposure to microplastics and plastic-associated chemicals.

2025 Probiotics and Antimicrobial Proteins 4 citations
Article Tier 2

Probiotics improve polystyrene microplastics-induced male reproductive toxicity in mice by alleviating inflammatory response

Researchers found that giving mice probiotics (beneficial bacteria including Lactobacillus and Bifidobacterium) helped protect against reproductive damage caused by polystyrene microplastics. The microplastics disrupted gut bacteria and triggered inflammation that traveled to the testes via the gut-testis connection, reducing sperm quality and testosterone levels. Probiotic treatment restored healthy gut bacteria and reduced the inflammatory response, suggesting that maintaining gut health could help counteract some reproductive harm from microplastic exposure.

2023 Ecotoxicology and Environmental Safety 65 citations
Systematic Review Tier 1

Interactions between polystyrene-derived micro- and nanoplastics and the microbiota: a systematic review of multi-omics mouse studies

Researchers systematically reviewed 15 mouse studies and found that exposure to polystyrene micro- and nanoplastics consistently disrupted gut bacteria — reducing beneficial species like Lactobacillus and increasing harmful ones — while also altering metabolic pathways throughout the body. Nanoplastics caused more severe microbiome disruption than larger microplastics, highlighting a serious health concern for humans.

2026 Journal of Environmental Science and Health Part C
Article Tier 2

The potential influence of food additives and contaminants on the gut microbiota: A comprehensive review

This comprehensive review examines how food additives and contaminants, including pesticides, heavy metals, microplastics, and antibiotics, affect the gut microbiota. Researchers found that these substances can disrupt the balance of gut microbes, leading to inflammation, gastrointestinal injury, and altered production of beneficial short-chain fatty acids. The study emphasizes the need for further research into the mechanisms by which dietary contaminants affect gut health and overall wellbeing.

2025 Food and Chemical Toxicology 1 citations
Article Tier 2

Black Lycium barbarum polysaccharide attenuates LPS-induced intestine damage via regulation gut microbiota

Researchers studied whether a polysaccharide from black Lycium barbarum could protect against intestinal damage caused by bacterial toxins in mice. They found that the supplement alleviated intestinal tissue damage and improved gut microbiota diversity by promoting beneficial bacteria. The study suggests that this plant-derived polysaccharide may help maintain intestinal health by modulating the gut microbial community.

2023 Frontiers in Microbiology 16 citations
Meta Analysis Tier 1

Unraveling Microplastic Effects on Gut Microbiota across Various Animals Using Machine Learning

This meta-analysis used machine learning to compare how microplastics affect gut bacteria across different animal species. Mice showed the strongest negative effects, including reduced gut bacterial diversity and imbalanced gut flora — shifts linked to health problems in humans too. The study identified specific bacterial markers, including Lactobacillus, that could help detect microplastic-related gut damage.

2024 ACS Nano 17 citations
Article Tier 2

Microplastics and probiotics: Mechanisms of interaction and their consequences for health

This review explores how microplastics interact with probiotics and what that means for gut health. Researchers summarized evidence showing that microplastics can disrupt the gut lining, alter the microbiome, and trigger inflammation, while certain probiotic strains may help counteract these effects by reducing oxidative stress and supporting the intestinal barrier. The study also discusses the emerging possibility of using engineered probiotics for environmental microplastic cleanup.

2025 AIMS Microbiology 4 citations
Article Tier 2

The microplastic-crisis: Role of bacteria in fighting microplastic-effects in the digestive system

This review examines how microplastics affect the human digestive system and explores whether certain bacteria could help counteract the damage. Microplastics disrupt the gut by altering microbial communities, interfering with digestive enzymes, and damaging the protective mucus lining. The authors highlight the potential for probiotic bacteria to bind to microplastics, reduce inflammation, and help repair the gut environment, offering a possible protective strategy against microplastic-related digestive harm.

2024 Environmental Pollution 12 citations
Article Tier 2

Microplastics and their interactions with microbiota

This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.

2023 Heliyon 64 citations