Papers

61,005 results
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Article Tier 2

Association of tetrabromobisphenol A (TBBPA) with micro/nano-plastics: A review of recent findings on ecotoxicological and health impacts

This review examines how tetrabromobisphenol A (TBBPA), a widely used flame retardant found in plastic products, binds to micro and nanoplastics in the environment. When TBBPA hitches a ride on microplastics, the combined effect on organisms and ecosystems is often worse than either contaminant alone. Since TBBPA is an additive in many plastic products, the findings highlight how microplastics can carry harmful chemicals directly into the body.

2024 The Science of The Total Environment 14 citations
Article Tier 2

Sorption of tetrabromobisphenol A onto microplastics: Behavior, mechanisms, and the effects of sorbent and environmental factors

The sorption of the flame retardant tetrabromobisphenol-A (TBBPA) onto four types of microplastics — polyethylene, polypropylene, polystyrene, and polyvinyl chloride — was studied in aqueous environments. Results revealed that polymer type, surface area, and hydrophobic interactions were key factors controlling how much TBBPA accumulates on microplastic surfaces.

2021 Ecotoxicology and Environmental Safety 77 citations
Article Tier 2

Further negative effect of fibrous microplastics to the bioaccumulation and toxicity of decabromodiphenyl ethane on zebrafish

Researchers investigated how fibrous microplastics from PET plastic interact with a common flame retardant chemical called DBDPE in zebrafish over 28 days. They found that microplastics significantly increased the amount of the flame retardant that accumulated in fish tissue and slowed its elimination from the body. The study suggests that microplastics may act as carriers for other toxic chemicals, amplifying their harmful effects on aquatic organisms.

2025 The Science of The Total Environment 3 citations
Article Tier 2

Encapsulation and release of tetrabromobisphenol A in microplastics: Trade-off in their individual toxicity to Xenopus tropicalis tadpoles

Researchers studied how the flame retardant TBBPA is distributed within and released from polystyrene microplastics, and tested the combined toxicity on tadpoles. They found a trade-off where microplastics that encapsulated the chemical reduced its immediate toxicity but created a slow-release exposure over time. The study highlights the complex relationship between microplastic-bound additives and their long-term effects on aquatic wildlife.

2024 Journal of Hazardous Materials 4 citations
Article Tier 2

Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics

Co-exposure of zebrafish to triphenyl phosphate (TPhP) with micro- or nano-polystyrene showed that nano-PS (46 nm) aggravated TPhP-induced liver and gonad enlargement, while micro-PS had minimal effect — suggesting nanoplastics can enhance the toxicity of organophosphate flame retardants.

2020 The Science of The Total Environment 81 citations
Article Tier 2

Aging relieves the promotion effects of polyamide microplastics on parental transfer and developmental toxicity of TDCIPP to zebrafish offspring

Researchers discovered that pristine polyamide microplastics promoted the transfer of the flame retardant TDCIPP from parent zebrafish to offspring and increased developmental toxicity, but aging of the microplastics reduced these harmful effects due to changed surface properties.

2022 Journal of Hazardous Materials 32 citations
Article Tier 2

Determination of Bisphenol Compounds and the Bioaccumulation after Co-Exposure with Polyethylene Microplastics in Zebrafish

Researchers developed a method to measure how bisphenol A and bisphenol S accumulate in zebrafish tissues when microplastics are also present. They found that microplastics increased the accumulation of these hormone-disrupting chemicals in fish tissues, with BPA building up more than BPS. The evidence indicates that microplastics can act as carriers that enhance the uptake of harmful chemicals by aquatic organisms.

2024 Toxics 5 citations
Article Tier 2

Interaction of tetrabromobisphenol A (TBBPA) with microplastics-sediment (MPs-S) complexes: A comparison between binary and simple systems

Researchers examined the adsorption of tetrabromobisphenol A (TBBPA) onto binary microplastic-sediment (MPs-S) complexes composed of PVC, PE, PP, and PS combined with natural sediment, finding that microplastics competed with sediment for adsorption sites, reduced TBBPA sorption relative to sediment-only systems, and that PVC-S showed the highest adsorption capacity.

2022 Environmental Pollution 19 citations
Article Tier 2

Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish

Researchers studied how polystyrene microplastics affect the toxicity of BHA, a synthetic antioxidant commonly used in plastics, on developing zebrafish. The study found that co-exposure to microplastics and BHA enhanced developmental toxicity by disrupting thyroid function and metabolism, suggesting that microplastics can amplify the harmful effects of their own chemical additives on aquatic organisms.

2020 Environment International 202 citations
Article Tier 2

Contrasting effects of micro- and nanoplastics on accumulation and toxicity of tris(1,3-dichloro-2-propyl) phosphate in zebrafish embryo revealed by toxicokinetic-toxicodynamic model

Researchers examined how microplastics and nanoplastics differently affect the accumulation and toxicity of the flame retardant TDCIPP in zebrafish embryos. The study found that while microplastics had minimal effect, nanoplastics significantly increased TDCIPP bioaccumulation and enhanced adverse effects on hatching, development, and survival, as validated by toxicokinetic and toxicodynamic modeling.

2026 Environmental Toxicology and Chemistry
Article Tier 2

Microplastics boost the accumulation of tetrabromobisphenol A in a commercial clam and elevate corresponding food safety risks

Researchers found that microplastics boosted the accumulation of the flame retardant tetrabromobisphenol A in commercial clams, elevating food safety risks for consumers of contaminated seafood from coastal areas.

2021 Chemosphere 41 citations
Article Tier 2

The influence of different polymer types of microplastics on adsorption, accumulation, and toxicity of triclosan in zebrafish

Researchers investigated how different polymer types of microplastics affect the toxicity and bioaccumulation of the antimicrobial chemical triclosan in zebrafish. They found that polypropylene microplastics had the highest capacity to adsorb triclosan and that co-exposure significantly worsened oxidative stress, lipid damage, and neurotoxicity compared to triclosan alone. The study demonstrates that the type of microplastic polymer matters when assessing the combined environmental risks of plastics and chemical pollutants.

2020 Journal of Hazardous Materials 162 citations
Article Tier 2

Influence of microplastic-associated biofilms on the bioavailability of a mixture of cadmium and benzo[a]pyrene by the analysis of biomarker gene expression in larval zebrafish

Researchers found that microbial biofilms — thin layers of bacteria that coat microplastics in water — selectively reduce how much of a toxic chemical called benzo[a]pyrene gets absorbed by larval zebrafish, while not affecting cadmium absorption, showing that microplastics can act as complex, biology-influenced carriers of multiple pollutants simultaneously.

2023 Ecological Indicators 10 citations
Article Tier 2

Sorption of PFOS onto polystyrene microplastics potentiates synergistic toxic effects during zebrafish embryogenesis and neurodevelopment

Researchers found that polystyrene microplastics can absorb PFOS (a persistent industrial chemical) from water and deliver it to zebrafish embryos in a more concentrated form. The combination caused worse developmental problems than either pollutant alone, including delayed hatching, higher death rates, birth defects, and impaired brain development. This shows microplastics can act as carriers that intensify the toxic effects of other environmental chemicals.

2024 Chemosphere 21 citations
Article Tier 2

Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish

Researchers found that nanoplastics amplify bisphenol A (BPA) accumulation in zebrafish tissues by 2- to 2.6-fold and that co-exposure enhances neurotoxic effects — including myelin disruption and dopaminergic system changes — beyond what either contaminant causes alone.

2017 The Science of The Total Environment 446 citations
Article Tier 2

Adsorption behaviors and bioavailability of tetrabromobisphenol A in the presence of polystyrene microplastic in soil: Effect of microplastics aging

Researchers studied how aging changes the ability of polystyrene microplastics to absorb and release a flame retardant chemical called TBBPA in soil. They found that aged microplastics had a greater capacity to adsorb the chemical but also released it more readily, increasing the bioavailability of this toxic compound to soil organisms. The study reveals that as microplastics weather in the environment, they may actually become more effective carriers of harmful chemicals into the food chain.

2023 Environmental Pollution 73 citations
Article Tier 2

Metabolic Consequences of Developmental Exposure to Polystyrene Nanoplastics, the Flame Retardant BDE-47 and Their Combination in Zebrafish

Researchers examined how developmental exposure to polystyrene nanoplastics and the flame retardant BDE-47, alone and combined, affects zebrafish metabolism, finding that co-exposure produced distinct metabolic disruptions beyond those caused by either contaminant individually.

2022 Frontiers in Pharmacology 23 citations
Article Tier 2

Effects of fibrous microplastics on the accumulation of tris(2,3-dibromopropyl) isocyanurate and behavior of zebrafish via water- and foodborne exposure routes

Researchers found that fibrous microplastics enhanced the accumulation of the flame retardant tris(2,3-dibromopropyl) isocyanurate in zebrafish and altered their swimming behavior, demonstrating how MP shape influences contaminant uptake and neurotoxicity.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish

Researchers examined whether contaminants sorbed to microplastics become bioavailable when ingested by larval zebrafish, using phenanthrene and ethinylestradiol as test chemicals. The study found that microplastics can alter the bioavailability of co-contaminants, as evidenced by changes in biomarker gene expression in the fish larvae.

2017 Marine Pollution Bulletin 183 citations
Article Tier 2

Influence of microplastics on bisphenol A and bisphenol AF toxicity in aquatic environments: Mechanistic insights for environmental risks

Researchers investigated how polyethylene microplastics interact with the industrial chemicals bisphenol A and bisphenol AF in zebrafish, finding that microplastics can either reduce or worsen the toxicity depending on the specific chemical and biological pathway involved. For bisphenol A, the microplastics partially absorbed the chemical and reduced its harmful effects, but for bisphenol AF, they worsened toxicity to certain organ systems. The study reveals that microplastics play a complicated dual role in modifying how other pollutants affect aquatic life.

2025 Journal of Hazardous Materials 4 citations
Article Tier 2

Effects of pristine or contaminated polyethylene microplastics on zebrafish development

Researchers examined the effects of both pristine and pollutant-contaminated polyethylene microplastics on zebrafish development through chronic exposure. The study assessed how microplastics, both alone and as carriers of adsorbed organic pollutants, affect developing fish. The findings provide new insights into how contaminated microplastics may create additional routes for toxic compounds to enter aquatic food webs.

2022 Chemosphere 66 citations
Article Tier 2

Recycled polyvinyl chloride microplastics: investigation of environmentally relevant concentrations on toxicity in adult zebrafish

Researchers investigated the toxicity of recycled PVC microplastics at environmentally relevant concentrations in adult zebrafish, finding that these particles release chemicals that cause measurable toxic effects in exposed organisms.

2023 Journal of Toxicology and Environmental Health 6 citations
Article Tier 2

Chemical Pollutants Sorbed to Ingested Microbeads from Personal Care Products Accumulate in Fish

Researchers investigated whether organic pollutants sorbed to microbeads from personal care products could accumulate in fish after ingestion. The study found that chemical pollutants adsorbed onto microplastic beads were indeed assimilated by rainbow fish following ingestion, providing evidence that microplastics can serve as a pathway for contaminant transfer through the food chain.

2016 Environmental Science & Technology 481 citations
Article Tier 2

Combined effects of microplastics and chemical contaminants on the organ toxicity of zebrafish ( Danio rerio )

Researchers studied the combined effects of microplastics and chemical contaminants like PCBs and methylmercury on zebrafish organs over three weeks of exposure. They found that microplastics carrying adsorbed contaminants produced the most significant effects, particularly on the liver, compared to either microplastics or contaminants alone. The results indicate that microplastics may act as carriers that increase the delivery of harmful chemicals to organisms' tissues.

2018 Environmental Research 406 citations