Papers

61,005 results
|
Article Tier 2

Regulation of Gene Expression in Fish

This paper is not relevant to microplastics research — it is a broad review of how environmental pollutants regulate gene expression in fish, covering heavy metals, pesticides, and endocrine disruptors.

2023 Fishes 1 citations
Article Tier 2

Microplastics: A tissue-specific threat to microbial community and biomarkers of discus fish (Symphysodon aequifasciatus)

Researchers found that polystyrene microplastics cause tissue-specific effects in discus fish, inhibiting growth, altering microbial communities in skin, gills, and intestine, and disrupting biomarker responses in a concentration-dependent manner after 28 days of exposure.

2021 Journal of Hazardous Materials 47 citations
Article Tier 2

Polyethylene microbeads induce transcriptional responses with tissue-dependent patterns in the mussel Mytilus galloprovincialis

Researchers exposed fish to polyethylene microbeads and measured gene expression across tissues, finding tissue-dependent transcriptional responses that suggest microplastic ingestion affects multiple physiological systems in distinct ways.

2017 Journal of Molluscan Studies 90 citations
Article Tier 2

Transcriptional effects of polyethylene microplastics ingestion in developing zebrafish (Danio rerio)

Researchers exposed developing zebrafish to polyethylene microplastics and used transcriptomic analysis to identify changes in gene expression related to immune function, lipid metabolism, and oxidative stress. The study suggests that even at relatively low concentrations, ingested microplastics can alter key biological pathways during early fish development.

2018 Environmental Pollution 176 citations
Article Tier 2

Lipid Metabolism and Oxidative Stress Altered in Crucian Carp (Carassius auratus) Following Exposure to Microplastics Under Laboratory and Field Conditions

Researchers used high-throughput sequencing to assess the impact of microplastics on crucian carp under both field and laboratory conditions. After four weeks of in-situ exposure, intestinal microplastic levels slightly increased, and transcriptome analysis revealed over 3,000 differentially expressed genes in the liver, with notable enrichment in pathways related to lipid metabolism and oxidative stress.

2026 Water
Article Tier 2

Do zebrafish have personality? Possible associations between behavioural patterns and personality traits in Danio rerio in the context of schizophrenia

Not relevant to microplastics — this paper explores whether zebrafish exhibit individual personality traits and how those traits might relate to modeling mental disorders such as schizophrenia.

2023 Bulletin of Integrative Psychiatry
Article Tier 2

Transcriptome alterations in zebrafish gill after exposure to different sizes of microplastics

Researchers found that microplastic exposure in zebrafish gills caused size-dependent transcriptomic changes, with smaller particles triggering more differentially expressed genes related to immune response, oxidative stress, and apoptosis pathways compared to larger particles.

2022 Journal of Environmental Science and Health Part A 36 citations
Article Tier 2

The effects of exposure to microplastics on grass carp (Ctenopharyngodon idella) at the physiological, biochemical, and transcriptomic levels

Researchers exposed grass carp to microplastics at two concentrations for 21 days and observed liver damage, inhibited growth, and increased oxidative stress. Transcriptome analysis revealed over 1,500 differentially expressed genes related to immune response, metabolism, and cellular stress pathways. The study suggests that microplastic exposure can trigger broad physiological and molecular disruptions in freshwater fish.

2021 Chemosphere 54 citations
Article Tier 2

Effects of zebrafish exposure to high-density polyethylene and polystyrene microplastics at molecular and histological levels

This study exposed zebrafish to high-density polyethylene and polystyrene microplastics and used genomic analysis to identify which biological pathways were most affected, finding widespread disruption of immune function, metabolism, and stress response genes. The transcriptomic approach reveals that different plastic types activate distinct molecular stress responses in fish.

2018 Use Siena air (University of Siena)
Article Tier 2

Characterization of skin- and intestine microbial communities in migrating High Arctic lake whitefish and cisco

This paper is not relevant to microplastics research — it characterizes the skin and gut microbiomes of Arctic lake whitefish and cisco as they migrate between freshwater and marine environments.

2023 Arctic Science
Article Tier 2

Physiological impacts of microplastics, heavy metals, and metallothionein in milkfish (Chanos chanos) in Jakarta Bay, Indonesia

Researchers analyzed concentrations of microplastics, metallothionein, and heavy metals in milkfish (Chanos chanos) sampled from Jakarta Bay, Indonesia, to assess how anthropogenic activities contribute to combined microplastic and heavy metal contamination in commercially important coastal fish.

2025 Journal of Animal Behaviour and Biometeorology
Article Tier 2

Uptake and transcriptional effects of polystyrene microplastics in larval stages of the Mediterranean mussel Mytilus galloprovincialis

Researchers exposed larval stages of a marine organism to polystyrene microplastics and measured gene expression changes, finding tissue-dependent transcriptional responses that suggest microplastics can affect development even at early life stages.

2018 Environmental Pollution 142 citations
Article Tier 2

Plastics in our water: Fish microbiomes at risk?

This review examined how microplastics and leached plasticizers affect the gut microbiomes of freshwater and marine fish, summarizing evidence for dysbiosis and reduced microbial diversity and discussing potential consequences for fish immunity, metabolism, and environmental fitness.

2021 Comparative Biochemistry and Physiology Part D Genomics and Proteomics 25 citations
Article Tier 2

The influence of microplastics and halogenated contaminants in feed on toxicokinetics and gene expression in European seabass (Dicentrarchus labrax)

Researchers studied how microplastics and halogenated contaminants in fish feed affected the toxicokinetics of those contaminants, finding that microplastics in feed altered how persistent organic pollutants were absorbed and distributed in fish tissues.

2018 Environmental Research 147 citations
Article Tier 2

Application of transcriptomic profiling to investigate the toxicity mechanisms caused by dietary exposure of nanoplastics in fish

Researchers used transcriptomic profiling to evaluate the impact of dietary nanoplastic exposure on European sea bass, finding changes in gene expression in intestinal tissue after 21 days of feeding with polystyrene nanoparticle-containing food. The study suggests that while no significant changes were observed in enzymatic stress markers, nanoplastics may trigger subtle molecular-level responses in the fish gut.

2023 Aquatic Toxicology 7 citations
Article Tier 2

Polystyrene microplastics induce gut microbiome and metabolome changes in Javanese medaka fish (Oryzias javanicus Bleeker, 1854)

Researchers found that polystyrene microplastic exposure altered gut microbiome composition and metabolic profiles in Javanese medaka fish, with effects on amino acid and lipid metabolism pathways suggesting microplastics can disrupt gut health in aquatic organisms.

2022 Toxicology Reports 33 citations
Article Tier 2

Sequencing data of Amphiprion ocellaris (clownfish) exposed to polystyrene nanoplastic

Researchers exposed clownfish to polystyrene nanoplastics at environmentally relevant and high concentrations for seven days and performed biochemical and transcriptomic analyses. The study found that even low-concentration exposure triggered significant gene expression changes indicating energy reallocation and stress responses, while high concentrations amplified these effects and activated additional inflammatory and detoxification pathways.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Micro/nano-plastics cause neurobehavioral toxicity in discus fish (Symphysodon aequifasciatus): Insight from brain-gut-microbiota axis

Researchers exposed juvenile discus fish to microfibers and nanoplastics and found that both types caused neurobehavioral problems, but through different mechanisms involving the brain-gut-microbiota axis. Nanoplastics weakened swimming and predatory abilities, while microfibers reduced growth, and both disrupted gut microbial communities that influence brain function. The study provides the first evidence linking microplastic-induced gut microbiome changes to neurological effects in fish through the gut-brain connection.

2021 Journal of Hazardous Materials 173 citations