Papers

20 results
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Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense

Researchers found that polystyrene nanoplastics significantly decreased molting frequency and induced oxidative stress in adult freshwater prawns, with effects on antioxidant enzyme activities observed at environmentally relevant concentrations.

2022 Fish & Shellfish Immunology 37 citations
Article Tier 2

Effects of nanoplastics on antioxidant and immune enzyme activities and related gene expression in juvenile Macrobrachium nipponense

Researchers explored the effects of nanoplastics on survival, antioxidant activity, immune enzyme activity, and gene expression in juvenile oriental river prawns. The study found that increasing nanoplastic concentrations suppressed antioxidant and immune enzyme activities while altering related gene expression levels, indicating that nanoplastic exposure can compromise the defense systems of freshwater crustaceans.

2020 Journal of Hazardous Materials 195 citations
Article Tier 2

Polystyrene nanoplastics decrease nutrient accumulation, disturb sex hormones, and inhibit reproductive development in juvenile Macrobrachium nipponense

Researchers exposed juvenile oriental river prawns to polystyrene nanoplastics at various concentrations for 28 days and observed significant disruptions to their reproductive development. The nanoplastics reduced nutrient accumulation, altered sex hormone levels, and interfered with genes involved in gonad development. The study suggests that nanoplastic pollution in waterways could impair the reproductive health of crustacean species.

2023 The Science of The Total Environment 22 citations
Article Tier 2

Effects of nanoplastic exposure on the growth performance and molecular characterization of growth-associated genes in juvenile Macrobrachium nipponense

Researchers found that polystyrene nanoplastic exposure impaired growth in juvenile shrimp by damaging the hepatopancreas, disrupting digestive enzyme activity, and altering growth-related gene expression at concentrations above 10 mg/L.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 22 citations
Article Tier 2

Effects of polystyrene nanoplastics on hormonal regulation and glucose metabolism of Pacific whiteleg shrimp (Litopenaeus vannamei)

High concentrations of polystyrene nanoplastics inhibited serum hormone levels, glucose metabolism enzyme activity, and related gene expression in Pacific white-leg shrimp (Litopenaeus vannamei). The study found nanoplastic exposure negatively affects glucose metabolites by inhibiting the pentose phosphate pathway, disrupting energy metabolism in an economically important aquaculture species.

2024 Environmental Science Nano 1 citations
Article Tier 2

Chronic exposure to polystyrene microplastics at environmentally relevant concentration induced growth retardation in Macrobrachium rosenbergii via multi-pathway toxicity: Oxidative stress, microbial dysbiosis, and biodistribution

Researchers exposed juvenile freshwater prawns to environmentally relevant concentrations of polystyrene microplastics for 42 days and found significant growth inhibition, with a 15.6% reduction in body length and 29.6% decrease in body weight. The microplastics accumulated in gills, stomachs, intestines, and hemolymph, causing persistent mitochondrial damage, oxidative stress, and gut microbiota imbalance that did not fully recover even after the exposure ended.

2026 Environmental Pollution
Article Tier 2

Effects of Microplastics, Polystyrene, and Polyethylene on Antioxidants, Metabolic Enzymes, HSP-70, and Myostatin Expressions in the Giant River Prawn Macrobrachium rosenbergii: Impact on Survival and Growth

Researchers exposed juvenile giant river prawns (Macrobrachium rosenbergii) to polystyrene microspheres and polyethylene microparticles and found that both types reduced survival and growth while increasing oxidative stress markers and altering expression of heat shock proteins and myostatin, with polystyrene causing more severe effects.

2021 Archives of Environmental Contamination and Toxicology 34 citations
Article Tier 2

Polystyrene nanoplastics induce apoptosis, histopathological damage, and glutathione metabolism disorder in the intestine of juvenile East Asian river prawns (Macrobrachium nipponense)

Researchers exposed juvenile East Asian river prawns to different concentrations of polystyrene nanoplastics for 28 days. They found that nanoplastic exposure caused intestinal cell death, tissue damage, and disrupted the glutathione antioxidant system in a dose-dependent manner. The study suggests that nanoplastic pollution in freshwater environments could significantly compromise the intestinal health and immune defenses of crustaceans.

2024 The Science of The Total Environment 5 citations
Article Tier 2

Gradual effects of gradient concentrations of polystyrene nanoplastics on metabolic processes of the razor clams

Researchers exposed razor clams to a gradient of polystyrene nanoplastic concentrations and used metabolomics to track effects, finding that even low concentrations disrupted energy metabolism and amino acid pathways, with effects becoming more severe as concentration increased.

2021 Environmental Pollution 47 citations
Article Tier 2

Effects of polystyrene nanoplastic exposure on energy metabolism, lipid metabolism, and amino acid changes in Monopterus albus

Researchers exposed Asian swamp eels to different concentrations of polystyrene nanoplastics over 35 days to study effects on metabolism. Evidence indicates that high concentrations of nanoplastics disrupted energy metabolism by altering gluconeogenic pathways and affected amino acid profiles, suggesting that nanoplastic ingestion through the food chain may pose metabolic risks to aquatic organisms.

2023 Frontiers in Marine Science 7 citations
Article Tier 2

Effects of Acute Exposure to Polystyrene Nanoplastics on the Channel Catfish Larvae: Insights From Energy Metabolism and Transcriptomic Analysis

Researchers found that acute exposure to polystyrene nanoplastics disrupted energy metabolism in channel catfish larvae, with transcriptomic analysis revealing altered gene expression in pathways related to oxidative stress and metabolic processes.

2022 Frontiers in Physiology 39 citations
Article Tier 2

Two genes related to apoptosis in the hepatopancreas of juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Researchers identified and characterized two apoptosis-related genes in juvenile prawns exposed to polystyrene nanoplastics, finding that nanoplastic exposure induced significant apoptotic responses in hepatopancreas tissue in a concentration-dependent manner.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Ecotoxicological effects of polystyrene nanoplastics on common carp: Insights into blood parameters, DNA damage, and gene expression

Exposing common carp to polystyrene nanoplastics caused significant DNA damage in blood and brain cells, along with changes in genes related to immune function and stress response. Higher concentrations led to more severe effects, and the nanoplastics also disrupted liver antioxidant defenses. Since carp are widely consumed fish, these findings raise questions about the safety of fish from nanoplastic-contaminated waters for human consumption.

2024 Journal of Applied Toxicology 14 citations
Article Tier 2

Time-dependent effects of polystyrene nanoparticles in brine shrimp Artemia franciscana at physiological, biochemical and molecular levels

Researchers tracked short- and long-term effects of cationic polystyrene nanoplastics on brine shrimp Artemia, finding that even low concentrations impair growth, trigger cumulative oxidative stress leading to lipid peroxidation, inhibit neural and developmental enzymes including cholinesterase and carboxylesterase, and alter gene expression governing molting and cell protection.

2019 The Science of The Total Environment 170 citations
Article Tier 2

Sub-chronic nanoplastic toxicity in Etroplus suratensis (Pisces, Cichilidae): Insights into tissue accumulation, stress and metabolic disruption

Researchers exposed pearl spot fish to polystyrene nanoplastics at different concentrations for 14 days and found that the particles accumulated in multiple organs with concentration-dependent distribution patterns. The nanoplastics caused elevated glucose and cholesterol levels, suppressed antioxidant defenses, and increased markers of oxidative damage and stress. Gene expression changes in stress response and growth-related genes suggest that nanoplastic exposure may impair both immune function and normal development in fish.

2025 Aquatic Toxicology 1 citations
Article Tier 2

Polystyrene nanoplastics induce lipid metabolism disorder and alter fatty acid composition in the hepatopancreas of Pacific whiteleg shrimp (Litopenaeus vannamei)

Researchers exposed Pacific whiteleg shrimp to different concentrations of polystyrene nanoplastics for 28 days and found significant disruption to fat metabolism in the shrimp's digestive organ. Higher concentrations caused tissue damage, reduced protein and fat content, and altered the activity of enzymes that control how the body processes fats. Since shrimp is a widely consumed seafood, these findings raise questions about how nanoplastic contamination in aquaculture could affect the nutritional quality and safety of shellfish for human consumption.

2023 The Science of The Total Environment 30 citations
Article Tier 2

Transcriptome sequencing and metabolite analysis reveal the toxic effects of nanoplastics on tilapia after exposure to polystyrene

Researchers exposed larval tilapia to polystyrene nanoplastics and then analyzed changes in gene expression and metabolic profiles after a recovery period. They found that nanoplastic exposure disrupted immune-related pathways, energy metabolism, and lipid processing in the fish, with some effects persisting even after exposure ended. The study suggests that nanoplastics can cause lasting metabolic and immune disruptions in freshwater fish.

2021 Environmental Pollution 69 citations
Article Tier 2

Changes in life-history traits, antioxidant defense, energy metabolism and molecular outcomes in the cladoceran Daphnia pulex after exposure to polystyrene microplastics

Researchers exposed the freshwater zooplankton Daphnia pulex to polystyrene microplastics and observed dose-dependent effects on survival, antioxidant capacity, and energy metabolism. The study found that microplastics accumulated in the digestive tract, caused lipid oxidative damage, disrupted sugar and fat metabolism, and activated DNA repair mechanisms while inhibiting lipid metabolism pathways.

2022 Chemosphere 42 citations
Article Tier 2

Effects of Sub-Chronic Exposure to Polystyrene Nanoplastics on Lipid and Antioxidant Metabolism in Sparus aurata

Researchers exposed gilthead seabream to polystyrene nanoplastics for 14 days and measured effects on blood, tissue, and gene expression. While the fish showed no visible tissue damage or changes in body condition, they had reduced hemoglobin levels and significant downregulation of genes related to fat metabolism, growth, and antioxidant defense. The study suggests that nanoplastics can cause subtle but meaningful biological changes in fish even when outward signs of harm are absent.

2025 Animals 4 citations