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61,005 resultsShowing papers similar to Research Advances on the Impact of Environmental Pollutants on Gut Microbiota
ClearToxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review
This review examines how various environmental pollutants affect the gut microbiome — the community of microorganisms in the intestinal tract. Microplastics are among the pollutants discussed, and their ability to alter gut microbiota composition is increasingly recognized as a mechanism by which plastic particles may harm human and animal health.
Interactions between environmental pollutants and gut microbiota: A review connecting the conventional heavy metals and the emerging microplastics
This review examines how environmental pollutants, including both heavy metals and microplastics, interact with gut bacteria in humans and animals. The authors found that these pollutants can disrupt the balance of gut microbiota, which may contribute to various health problems, and that gut bacteria can also transform pollutants in ways that change their toxicity.
Impacts of microplastics on gut health: Current status and future directions
This systematic review found consistent evidence across mouse, fish, and earthworm models that microplastics disrupt gut microbiota composition, impair intestinal barrier integrity, and trigger gastrointestinal inflammation. The correlation between microplastic exposure and gut health deterioration was statistically significant across all animal models examined.
Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction
This review examined the bidirectional relationship between environmental pollutants, including microplastics, and the human gut microbiota, highlighting how toxicants alter microbial communities while gut bacteria can metabolize or modify pollutant toxicity.
Pollutants, microbiota and immune system: frenemies within the gut
This review summarizes how environmental pollutants, including microplastics, disrupt the gut microbiome and immune system, potentially contributing to inflammatory bowel diseases and colorectal cancer. Pollutants reduce beneficial gut bacteria while promoting inflammation, weakening the intestinal barrier, and triggering a chain of events that can push cells toward cancerous growth.
Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health
This review explores how microplastics interact with microorganisms in the environment and within the gut, examining implications for both animal and human health. Researchers found that microplastics can alter gut microbiota composition, promote the spread of antibiotic-resistant bacteria, and amplify the toxicity of other environmental pollutants. The study suggests that the interaction between microplastics and gut microorganisms is an important emerging area for understanding health risks.
Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review
This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.
Impact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Health
This review examines cumulative exposure to environmental and dietary xenobiotics including microplastics, pesticides, and food additives, assessing their combined impact on the human gut microbiome within a One Health risk framework.
Microplastic: A potential threat to human and animal health by interfering with the intestinal barrier function and changing the intestinal microenvironment
This review summarizes current research on how microplastics disrupt the gut environment in both animals and humans, focusing on damage to the intestinal barrier. Studies show that microplastic exposure can cause oxidative damage, inflammation, destruction of the gut lining, thinning of the protective mucus layer, and disruption of beneficial gut bacteria. While direct human evidence is still limited, the growing body of animal research suggests that microplastics could pose a meaningful threat to intestinal health.
Gut microbiota as an emerging target for the health implications of microplastics
This review examines how microplastic exposure disrupts the gut microbiome, finding evidence that microplastics damage intestinal barrier proteins, promote inflammation and oxidative stress, and may drive systemic effects including neurotoxicity and reproductive toxicity through gut-mediated pathways.
Potential effects of MPs and their co-pollutants on human intestinal tract
This review examines how microplastics and their co-pollutants enter and damage the human intestinal tract, summarizing evidence for microplastic-induced gut barrier disruption, microbiota alteration, and systemic translocation to other organs.
The ant that may well destroy a whole dam: a systematic review of the health implication of nanoplastics/microplastics through gut microbiota
This systematic review summarizes existing research on how nanoplastics and microplastics disrupt gut bacteria in various organisms. The findings show that plastic particle exposure consistently alters gut microbiome composition, which in turn affects the host's immune function, metabolism, and overall health. These gut bacteria changes may be a key pathway through which microplastics harm human health.
The potential influence of food additives and contaminants on the gut microbiota: A comprehensive review
This comprehensive review examines how food additives and contaminants, including pesticides, heavy metals, microplastics, and antibiotics, affect the gut microbiota. Researchers found that these substances can disrupt the balance of gut microbes, leading to inflammation, gastrointestinal injury, and altered production of beneficial short-chain fatty acids. The study emphasizes the need for further research into the mechanisms by which dietary contaminants affect gut health and overall wellbeing.
Gut microbiome remodeling induced by microplastic exposure in humans
This review synthesizes evidence on how microplastic exposure affects the human gut microbiome, drawing on cross-sectional studies of people exposed through plastic food containers and other sources. Evidence indicates that microplastic exposure is associated with shifts in gut bacteria composition, including increases in certain bacterial groups linked to inflammation. The authors explore potential connections between microplastic-induced changes in gut bacteria and the development of various health conditions.
Interactions between gut microbiota and emerging contaminants exposure: new and profound implications for human health
This review explores how emerging contaminants like microplastics, antibiotics, and persistent organic pollutants interact with gut bacteria and what that means for human health. Researchers found that the gut microbiome is a key target of these pollutants and may play a role in organ damage, hormonal disruption, and other toxic effects through pathways like the gut-liver and gut-brain axes. The study underscores the importance of understanding the three-way relationship between environmental contaminants, gut bacteria, and overall health.
Toxic Effects of Xenobiotics on Gut Microbiome and Host Health: A Mini-Review
This mini-review examines how xenobiotics including heavy metals, pharmaceuticals, air pollutants, persistent organic pollutants, and microplastics disrupt the gut microbiome and host health, with implications for developing targeted therapies.
Microplastics and their interactions with microbiota
This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.
Impact of microplastics on the human gut microbiome: a systematic review of microbial composition, diversity, and metabolic disruptions
This systematic review of 12 studies found that microplastics including polyethylene, polystyrene, and PVC induce gut dysbiosis in humans, reducing beneficial bacteria and enriching pathogens. Microplastic exposure also impairs short-chain fatty acid production and modulates immune pathways, contributing to intestinal disease, metabolic syndrome, and chronic inflammation.
Effects of environmental factors on host-microbiota interactions in the guts of aquatic organisms: A review
This review synthesizes how environmental stressors — including microplastics, heavy metals, photoperiod, and aquaculture feed additives — alter gut microbiota in fish and aquatic invertebrates, identifying common patterns of microbial disruption and compromised gut barrier integrity.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks
This review summarizes evidence that microplastics disrupt the gut microbiome, the community of bacteria in our digestive system that plays a key role in immunity, metabolism, and overall health. By altering gut bacteria balance and triggering inflammation, microplastic exposure may contribute to chronic conditions including inflammatory bowel disease, metabolic disorders, and potentially even neurological problems through the gut-brain connection.
Perturbation of gut microbiota plays an important role in micro/nanoplastics-induced gut barrier dysfunction
Researchers investigated how micro- and nanoplastics disrupt gut barrier function in mice, finding that different surface chemistries caused varying levels of damage. The study suggests that these plastic particles harm the gut by altering the gut microbiome, which then leads to inflammation and weakening of the intestinal barrier that normally keeps harmful substances out of the body.
Role of Gut Microbiota in Modulating Oxidative Stress Induced by Environmental Factors
This review examines how environmental pollutants, including microplastics, toxic metals, and antibiotics, disrupt the balance of gut bacteria and trigger oxidative stress throughout the body. The resulting gut dysbiosis impairs the production of beneficial molecules, weakens the intestinal barrier, and activates inflammatory pathways linked to chronic disease. The review also discusses therapeutic interventions like probiotics and polyphenols that may help restore gut health and counteract pollutant-driven damage.
Adverse health effects of emerging contaminants on inflammatory bowel disease
This review summarizes how emerging environmental contaminants, including microplastics, endocrine disruptors, herbicides, and heavy metals, may contribute to inflammatory bowel disease. Researchers found evidence that these pollutants can disrupt gut barrier function, alter the microbiome, and trigger immune responses linked to bowel inflammation. The study suggests that reducing exposure to these increasingly common contaminants could help lower the rising incidence of inflammatory bowel disease.