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Papers
61,005 resultsShowing papers similar to Application of Hydrogel as Drug Carrier in Tumor Therapy
ClearHydrogel-based nanoparticles: revolutionizing brain tumor treatment and paving the way for future innovations
Researchers reviewed how nanoparticles embedded in hydrogels — water-based gel materials — can serve as targeted drug delivery vehicles for brain tumors by crossing the blood-brain barrier, a major obstacle that blocks most medications from reaching the brain. These systems have shown improved survival rates in studies, and the review outlines remaining challenges around manufacturing, stability, and scaling up for clinical use.
Hydrogels: A Comprehensive Review of Structure, Properties, and Multifaceted Applications
This review provides a systematic overview of hydrogel classification, cross-linking mechanisms, and properties, examining their applications in drug delivery, tissue engineering, soft robotics, and sustainable agriculture, and discussing stimuli-responsive behavior and emerging directions in the field.
Synthetic Polymer-based Hydrogels and Properties
Researchers reviewed the synthesis, properties, and applications of synthetic polymer-based hydrogels, summarizing advances in zwitterionic and hybrid formulations that overcome brittleness and poor toughness to enable uses from drug delivery to neural interfaces and bioelectronic devices.
Nanoparticles in Drug Delivery
This review examines how nanoparticles made from various materials, including polymers, are being developed for targeted drug delivery across biological barriers. Researchers highlighted advances in stimuli-responsive nanoparticle engineering for tumor targeting and the integration of AI models for personalized medicine. While focused on biomedical applications, the study is relevant to understanding how polymer-based particles interact with biological systems at the nanoscale.
Fundamentals and Advances in Stimuli-Responsive Hydrogels and Their Applications: A Review
This review covers stimuli-responsive hydrogels, which are smart materials that change shape or behavior in response to environmental triggers. Among their many applications, these materials can remove heavy metals and pollutants from water, and they show promise in biomedical settings like drug delivery and wound healing. While not focused specifically on microplastics, these technologies could be adapted for environmental cleanup of plastic pollution.
Hydrogel-Based Stimuli-Responsive Micromotors for Biomedicine
This review summarized progress in hydrogel-based micromotors that respond to stimuli such as temperature, pH, and magnetic fields for biomedical applications. The study suggests these tiny devices could transport drugs or capture targets in hard-to-reach areas of the body, offering potential for minimally invasive diagnosis and therapy.
Advances in Drug Targeting, Drug Delivery, and Nanotechnology Applications: Therapeutic Significance in Cancer Treatment
This review covers advances in targeted drug delivery using nanotechnology, including nanoparticles and liposomes designed to release medications precisely where needed in the body. While focused on cancer treatment, the drug delivery technologies discussed are relevant to understanding how nanoscale plastic particles may also travel through the body and accumulate in specific tissues.
Polymer-based nanocarriers for biomedical and environmental applications
This review covers the fabrication, design, and applications of polymer-based nanocarriers in biomedical and environmental fields. The study highlights their use in targeted drug delivery and cancer therapy, as well as their ability to remove heavy metals and contaminants from air and water, while noting current challenges for future development.
Polyethylene Glycol-Based Polymer-Drug Conjugates: Novel Design and Synthesis Strategies for Enhanced Therapeutic Efficacy and Targeted Drug Delivery
This paper is not about microplastics — it reviews the design and synthesis of polyethylene glycol (PEG)-based polymer-drug conjugates as targeted drug delivery systems for cancer and other diseases, with no relevance to microplastic pollution or environmental health.
Significance of biopolymer-based hydrogels and their applications in agriculture: a review in perspective of synthesis and their degree of swelling for water holding
Researchers reviewed the development and agricultural applications of hydrogels made from natural biopolymers, which are biodegradable alternatives to synthetic plastics. These hydrogels can retain large amounts of water and deliver nutrients or active compounds to soil in a controlled way. The study suggests that biopolymer hydrogels could help improve crop yields while reducing the environmental burden of synthetic plastic materials in agriculture.
Hydrogel-based nanocomposites for enhanced environmental remediation
A review covered hydrogel-based nanocomposites engineered to adsorb and remove pollutants including microplastics from water. These materials show promise as efficient, tunable sorbents for environmental remediation applications.
Tough Hydrogels with Different Toughening Mechanisms and Applications
This review examines advances in engineering tough hydrogels that can withstand significant mechanical stress, mimicking the properties of load-bearing biological tissues like cartilage and muscle. Researchers summarized various toughening strategies including double-network designs and nanocomposite reinforcement. The study highlights the potential of these materials for biomedical applications such as tissue engineering, wound healing, and soft robotics.
Enhancing Hydrogels with Quantum Dots
This review explores the integration of quantum dots with hydrogel materials for applications in biomedical engineering, environmental sensing, and energy harvesting. The authors highlight innovations including fluorescent nanocomposites for environmental monitoring and smart sensors capable of detecting biological and environmental changes, while noting challenges in scaling these technologies for commercial use.
A review on micro beads: Formulation, technological aspects, and extraction
This review covered the formulation, technological aspects, and extraction methods for microbead drug delivery systems, which are used to achieve targeted therapeutic drug concentrations in the body. The paper compared different types of unit dosage forms and discussed the advantages of microbeads for controlled drug release.
Progress, challenge and perspective of hydrogels application in food: a review
Researchers reviewed how hydrogels — water-absorbing polymer networks — can be engineered to detect and remove food contaminants including microplastics, heavy metals, and pesticides, as well as to extend food shelf life. While hydrogels show broad promise for food safety applications, the review notes challenges around scalability and the need for further real-world testing.
Evaluation of properties for synthetic polymers in medicine
This review examines the properties and biomedical applications of synthetic polymers, covering their use in drug delivery, tissue engineering, cardiovascular devices, and implants, with synthetic polymers accounting for the majority of new pharmaceutical and therapeutic research applications.
Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases
This review examines biodegradable nanomaterials designed to deliver drugs precisely to treat autoimmune diseases, releasing medications in response to specific body signals like pH or temperature changes. While focused on drug delivery, the responsive behavior of these biodegradable nanoparticles in the body parallels how micro- and nanoplastics interact with biological systems and accumulate in tissues.
Spray-Dried Chitosan Hydrogel Particles as a Potential Delivery System for Benzydamine Hydrochloride
Researchers developed spray-dried chitosan hydrogel microparticles as potential drug delivery systems for benzydamine hydrochloride. The study explored different formulation approaches using crosslinking and coating techniques, contributing to biodegradable polymer research that offers alternatives to conventional plastic-based pharmaceutical delivery materials.
Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle.
This study tested polymer microparticles as a delivery system for a cancer drug in brain tumor models. This is a drug delivery and cancer treatment research paper with no direct connection to environmental microplastics.
Polymeric Hydrogelsin Agriculture: EnvironmentalPerformance, Sustainability Challenges, and Future Perspectives
This review examines polymeric hydrogels as soil amendments for climate-smart agriculture, finding that these cross-linked water-swelling networks can improve soil moisture retention, reduce irrigation frequency, and enhance fertilizer utilization, while also addressing environmental persistence and degradation challenges.
Biomembrane-wrapped gene delivery nanoparticles for cancer therapy
This review examined biomembrane-wrapped nanoparticles as gene delivery vehicles for cancer therapy, highlighting how cell membrane coatings improve targeting, immune evasion, and therapeutic efficacy compared to conventional synthetic delivery systems.
Advances in Controlled Release Fertilizers: Cost‐Effective Coating Techniques and Smart Stimuli‐Responsive Hydrogels
This review examines advances in controlled release fertilizer technology, focusing on cost-effective coating techniques and smart hydrogels that release nutrients in response to environmental conditions. Researchers found that while these technologies improve nutrient efficiency and reduce environmental pollution from fertilizer runoff, the coatings themselves can introduce microplastic contamination into soils. The study calls for development of fully biodegradable coating materials that deliver the benefits of controlled release without adding to plastic pollution in agricultural lands.
Water-Content-Dependent Switching of the Bending Behavior of Photoresponsive Hydrogels Composed of Hydrophilic Acrylamide-Based Main Chains and Hydrophobic Azobenzene
This materials study developed hydrogels that respond to both light and water content, with potential applications in soft robotics and drug delivery. Smart hydrogel materials represent an emerging class of polymers whose environmental fate and potential for microplastic generation warrant study.
Polymeric Hydrogels in Agriculture: Environmental Performance, Sustainability Challenges, and Future Perspectives
A review assessed the environmental performance and degradation behavior of polymeric hydrogels used in agriculture as soil moisture-retaining agents. The study raises concerns about whether these materials break down safely or contribute to microplastic accumulation in farmland soils.