Papers

61,005 results
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Article Tier 2

Effects of nanoplastics on antioxidant and immune enzyme activities and related gene expression in juvenile Macrobrachium nipponense

Researchers explored the effects of nanoplastics on survival, antioxidant activity, immune enzyme activity, and gene expression in juvenile oriental river prawns. The study found that increasing nanoplastic concentrations suppressed antioxidant and immune enzyme activities while altering related gene expression levels, indicating that nanoplastic exposure can compromise the defense systems of freshwater crustaceans.

2020 Journal of Hazardous Materials 195 citations
Article Tier 2

Polystyrene nanoplastics induce apoptosis, histopathological damage, and glutathione metabolism disorder in the intestine of juvenile East Asian river prawns (Macrobrachium nipponense)

Researchers exposed juvenile East Asian river prawns to different concentrations of polystyrene nanoplastics for 28 days. They found that nanoplastic exposure caused intestinal cell death, tissue damage, and disrupted the glutathione antioxidant system in a dose-dependent manner. The study suggests that nanoplastic pollution in freshwater environments could significantly compromise the intestinal health and immune defenses of crustaceans.

2024 The Science of The Total Environment 5 citations
Article Tier 2

Chronic exposure to polystyrene microplastics at environmentally relevant concentration induced growth retardation in Macrobrachium rosenbergii via multi-pathway toxicity: Oxidative stress, microbial dysbiosis, and biodistribution

Researchers exposed juvenile freshwater prawns to environmentally relevant concentrations of polystyrene microplastics for 42 days and found significant growth inhibition, with a 15.6% reduction in body length and 29.6% decrease in body weight. The microplastics accumulated in gills, stomachs, intestines, and hemolymph, causing persistent mitochondrial damage, oxidative stress, and gut microbiota imbalance that did not fully recover even after the exposure ended.

2026 Environmental Pollution
Article Tier 2

Effects of Microplastics, Polystyrene, and Polyethylene on Antioxidants, Metabolic Enzymes, HSP-70, and Myostatin Expressions in the Giant River Prawn Macrobrachium rosenbergii: Impact on Survival and Growth

Researchers exposed juvenile giant river prawns (Macrobrachium rosenbergii) to polystyrene microspheres and polyethylene microparticles and found that both types reduced survival and growth while increasing oxidative stress markers and altering expression of heat shock proteins and myostatin, with polystyrene causing more severe effects.

2021 Archives of Environmental Contamination and Toxicology 34 citations
Article Tier 2

Effects of nanoplastics on energy metabolism in the oriental river prawn (Macrobrachium nipponense)

Oriental river prawns exposed to polystyrene nanoplastics (5–40 mg/L) for up to 28 days showed concentration- and time-dependent decreases in survival and energy metabolism, including disrupted glycogen and triglyceride content, reduced metabolic enzyme activity, and altered gene expression of energy pathways.

2020 Environmental Pollution 110 citations
Article Tier 2

Polystyrene nanoplastics decrease nutrient accumulation, disturb sex hormones, and inhibit reproductive development in juvenile Macrobrachium nipponense

Researchers exposed juvenile oriental river prawns to polystyrene nanoplastics at various concentrations for 28 days and observed significant disruptions to their reproductive development. The nanoplastics reduced nutrient accumulation, altered sex hormone levels, and interfered with genes involved in gonad development. The study suggests that nanoplastic pollution in waterways could impair the reproductive health of crustacean species.

2023 The Science of The Total Environment 22 citations
Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

Time-dependent effects of polystyrene nanoparticles in brine shrimp Artemia franciscana at physiological, biochemical and molecular levels

Researchers tracked short- and long-term effects of cationic polystyrene nanoplastics on brine shrimp Artemia, finding that even low concentrations impair growth, trigger cumulative oxidative stress leading to lipid peroxidation, inhibit neural and developmental enzymes including cholinesterase and carboxylesterase, and alter gene expression governing molting and cell protection.

2019 The Science of The Total Environment 170 citations
Article Tier 2

Effects of nanoplastic exposure on the growth performance and molecular characterization of growth-associated genes in juvenile Macrobrachium nipponense

Researchers found that polystyrene nanoplastic exposure impaired growth in juvenile shrimp by damaging the hepatopancreas, disrupting digestive enzyme activity, and altering growth-related gene expression at concentrations above 10 mg/L.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 22 citations
Article Tier 2

Toxicokinetics of microplastics in Macrobrachium nipponense and their impact on the bioavailability of loaded pollutants

Researchers studied the toxicokinetics of microplastics in the freshwater prawn Macrobrachium nipponense, tracking uptake, distribution, and clearance across tissues and examining impacts on antioxidant defenses and immune function.

2024 Journal of Hazardous Materials 5 citations
Article Tier 2

Behavioural, physiological and molecular responses of the Antarctic fairy shrimp Branchinecta gaini (Daday, 1910) to polystyrene nanoplastics

Researchers exposed Antarctic fairy shrimp — a species isolated in pristine polar freshwater lakes — to polystyrene nanoplastics and found that amino-functionalized particles caused increased moulting, gut epithelium damage, altered ventilation behavior, and upregulation of stress response genes, suggesting nanoplastics could threaten unique Antarctic freshwater biodiversity.

2022 NanoImpact 21 citations
Article Tier 2

Determination of bioaccumulation of polystyrene nanoplastics in mussel Mytilus galloprovincialis and their impact on enzymatic and nonenzymatic antioxidative stress mechanisms

Researchers assessed the bioaccumulation of polystyrene nanoplastics in the mussel Mytilus galloprovincialis and measured enzymatic and non-enzymatic antioxidant stress responses after 4 days of exposure to 1 mg/L of 54 nm particles. Nanoplastics accumulated in mussel tissues and triggered significant oxidative stress responses, including altered superoxide dismutase and catalase activity, indicating toxicological effects at environmentally relevant concentrations.

2024 Juraj Dobrila University of Pula Digital Repository
Article Tier 2

Two genes related to reproductive development in the juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Nanoplastic exposure altered the expression of two genes involved in reproductive development in juvenile freshwater prawns (Macrobrachium nipponense), suggesting that nanoplastics may disrupt reproductive pathways in crustaceans at low concentrations.

2021 Chemosphere 17 citations
Article Tier 2

Toxicological effects of polystyrene nanoplastics on marine organisms

Researchers exposed Pacific white shrimp to polystyrene nanoplastics at various concentrations and measured immune, antioxidant, and tissue responses after seven days. They found that nanoplastic exposure disrupted immune function, increased oxidative stress, and caused tissue damage, particularly in the hepatopancreas and gills. The study adds to growing evidence that nanoplastics can harm the health of commercially important marine species.

2023 Environmental Technology & Innovation 32 citations
Article Tier 2

Two genes related to apoptosis in the hepatopancreas of juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Researchers identified and characterized two apoptosis-related genes in juvenile prawns exposed to polystyrene nanoplastics, finding that nanoplastic exposure induced significant apoptotic responses in hepatopancreas tissue in a concentration-dependent manner.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Nanopolystyrene particles at environmentally relevant concentrations causes behavioral and biochemical changes in juvenile grass carp (Ctenopharyngodon idella)

Researchers exposed juvenile grass carp to environmentally relevant concentrations of polystyrene nanoplastics and found impaired anti-predator behavior, altered shoal dynamics, and increased acetylcholinesterase activity alongside oxidative stress, with nanoplastics detected in brain tissue, suggesting neurological effects even at trace exposure levels.

2020 Journal of Hazardous Materials 84 citations
Article Tier 2

Polystyrene Microparticles and the Functional Traits of Invertebrates: A Case Study on Freshwater Shrimp Neocardina heteropoda

Researchers exposed freshwater shrimp to polystyrene microplastics and found measurable changes in behavioral and physiological functional traits, contributing evidence that microplastic pollution poses risks to freshwater invertebrate communities beyond the marine environments typically studied.

2022 Fishes 5 citations
Article Tier 2

Ecotoxicological effects of polystyrene nanoplastics on common carp: Insights into blood parameters, DNA damage, and gene expression

Exposing common carp to polystyrene nanoplastics caused significant DNA damage in blood and brain cells, along with changes in genes related to immune function and stress response. Higher concentrations led to more severe effects, and the nanoplastics also disrupted liver antioxidant defenses. Since carp are widely consumed fish, these findings raise questions about the safety of fish from nanoplastic-contaminated waters for human consumption.

2024 Journal of Applied Toxicology 14 citations
Article Tier 2

Polystyrene nanoplastic exposure induces immobilization, reproduction, and stress defense in the freshwater cladoceran Daphnia pulex

Researchers documented how polystyrene nanoplastics accumulate in the guts of the freshwater crustacean Daphnia pulex and cause chronic toxicity at environmentally relevant concentrations, delaying reproduction, reducing offspring numbers, and inducing then suppressing antioxidant defense genes over a 21-day exposure.

2018 Chemosphere 285 citations
Article Tier 2

Acute and chronic effects of polystyrene microplastics on brine shrimp: First evidence highlighting the molecular mechanism through transcriptome analysis

Researchers investigated both acute and chronic toxicity of polystyrene microplastics on brine shrimp, using transcriptome analysis to uncover molecular mechanisms. While acute exposure did not significantly affect survival, chronic exposure led to concentration-dependent bioaccumulation and increased reactive oxygen species generation, with gene expression analysis revealing disrupted metabolic and stress response pathways.

2020 Journal of Hazardous Materials 176 citations
Systematic Review Tier 1

Invertebrate responses to microplastic ingestion: Reviewing the role of the antioxidant system

Microplastic ingestion poses an oxidative challenge to invertebrates requiring upregulation of antioxidant defenses, but studies are limited to only seven taxa, dominated by polystyrene spheres <10 µm, and the lack of systematic experiments prevents identifying which specific microplastic characteristics drive the oxidative stress response.

2020 The Science of The Total Environment 208 citations
Article Tier 2

Polystyrene microplastics induced male reproductive toxicity and transgenerational effects in freshwater prawn

Researchers found that polystyrene microplastics caused significant reproductive harm in male freshwater prawns, including oxidative stress in testis tissue, hormonal imbalances, and reduced sperm quality. Notably, the offspring of exposed prawns also showed reduced survival and weakened immunity even when they were not directly exposed to microplastics. The study reveals that microplastic exposure can produce transgenerational effects in aquatic organisms, passing harm from parents to offspring.

2022 The Science of The Total Environment 85 citations
Article Tier 2

Do Waterborne Nanoplastics Affect the Shore Crab Carcinus maenas? A Case Study with Poly(methyl)methacrylate Particles

Researchers exposed shore crabs (Carcinus maenas) to waterborne nanoplastics and assessed multiple physiological endpoints, finding that nanoplastic exposure altered immune function, oxidative stress markers, and gene expression in ways that indicate significant sublethal harm to this ecologically important species.

2025 Environments
Article Tier 2

Changes in life-history traits, antioxidant defense, energy metabolism and molecular outcomes in the cladoceran Daphnia pulex after exposure to polystyrene microplastics

Researchers exposed the freshwater zooplankton Daphnia pulex to polystyrene microplastics and observed dose-dependent effects on survival, antioxidant capacity, and energy metabolism. The study found that microplastics accumulated in the digestive tract, caused lipid oxidative damage, disrupted sugar and fat metabolism, and activated DNA repair mechanisms while inhibiting lipid metabolism pathways.

2022 Chemosphere 42 citations