Papers

61,005 results
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Article Tier 2

Occurrence, fate, and risk assessment of antibiotics in typical pharmaceutical manufactories and receiving water bodies from different regions

Researchers surveyed four pharmaceutical manufacturing facilities in China and found thirteen different antibiotics in their wastewater and nearby receiving water bodies at concentrations up to 727 nanograms per liter. Fluoroquinolones and macrolides were the most prevalent classes, and while wastewater treatment removed some antibiotics, significant residues persisted in the environment. The study highlights pharmaceutical manufacturing as an important source of antibiotic pollution in waterways.

2023 PLoS ONE 52 citations
Article Tier 2

A Review of the Distribution of Antibiotics in Water in Different Regions of China and Current Antibiotic Degradation Pathways

This review summarized the spatial and temporal distribution of antibiotic contamination across major Chinese water bodies, identifying livestock farming, pharmaceutical manufacturing, and aquaculture as primary sources and reviewing current biological and physicochemical degradation pathways.

2021 Frontiers in Environmental Science 161 citations
Review Tier 2

Review on Biogeochemical Characteristics of Typical Antibiotics in Groundwater in China

A systematic review of antibiotic contamination in Chinese groundwater found 65 antibiotics detected across the country, with sulfonamides and quinolones most studied, maximum concentrations reaching 47,444.5 ng/L in some locations, and ecological risk mostly low to medium across monitored areas.

2023 Sustainability 15 citations
Review Tier 2

Proclivities for prevalence and treatment of antibiotics in the ambient water: a review

This review critically examines the prevalence of antibiotics in ambient water systems and the challenges of treating antibiotic-contaminated water. Researchers found that antibiotic resistance in water environments has emerged as a major public health concern, driven by pharmaceutical runoff and inadequate wastewater treatment. The study evaluates various treatment technologies and emphasizes the need for better monitoring and removal strategies to address this growing threat to water quality.

2020 npj Clean Water 161 citations
Article Tier 2

The Current Status and Prevention of Antibiotic Pollution in Groundwater in China

This review systematically described antibiotic sources, migration, transformation, contamination levels, and ecological risks in Chinese groundwater, finding that antibiotic pollution is widespread and poses growing risks to drinking water quality and aquatic ecosystems. The authors identified gaps in monitoring and called for stronger regulatory controls on antibiotic discharge to groundwater.

2022 International Journal of Environmental Research and Public Health 60 citations
Article Tier 2

The Occurrence, Distribution, Environmental Effects, and Interactions of Microplastics and Antibiotics in the Aquatic Environment of China

This review characterizes the co-occurrence of microplastics and antibiotics in Chinese aquatic environments, summarizing their sources, spatial distributions, and the environmental effects of their interactions.

2024 Water 8 citations
Article Tier 2

Accumulation of antibiotics in the environment: Have appropriate measures been taken to protect Canadian human and ecological health?

This review examines how antibiotics and other contaminants of emerging concern, including microplastics, are legally discharged into Canadian freshwater from treatment plants and accumulate in the environment. The buildup of these substances raises concerns about antibiotic resistance and ecosystem disruption, with potential downstream effects on human health through contaminated drinking water and food sources.

2024 Ecotoxicology and Environmental Safety 21 citations
Article Tier 2

The occurence of pharmaceuticals and other micropollutants in wastewater treatment plant in the aspect of interaction with microplastics

Researchers analysed the occurrence of antibiotics, virucidal, and fungicidal pharmaceuticals in raw and treated sewage at a wastewater treatment plant in southern Poland, examining their removal efficiency and potential interactions with microplastics present in the effluent. The study found that pharmaceutical micropollutants persisted through treatment to varying degrees, raising concerns about combined contamination pathways when microplastics act as co-vectors for these compounds.

2024 1 citations
Article Tier 2

Pharmaceutically active micropollutants: origin, hazards and removal

This review summarizes existing research on pharmaceutical pollutants -- such as antibiotics, painkillers, and hormones -- found in water systems around the world. While focused on drug contamination, the paper notes that microplastics can act as carriers for these pharmaceutical chemicals, potentially concentrating them and increasing human exposure through drinking water. Conventional water treatment methods are often unable to fully remove these micropollutants.

2024 Frontiers in Microbiology 37 citations
Article Tier 2

Occurrence and ecological risks of pharmaceuticals in a Mediterranean river in Eastern Spain

Researchers monitored a Spanish Mediterranean river and detected up to 69 pharmaceutical compounds in the water, with painkillers and antibiotics posing the highest ecological risk — affecting an estimated 65–82% of aquatic species in areas near wastewater treatment plant outflows. Five antibiotics exceeded thresholds linked to antibiotic resistance, raising concerns that standard wastewater treatment is insufficient to protect river ecosystems.

2020 Environment International 128 citations
Article Tier 2

Characterization of microplastics and their interaction with antibiotics in wastewater

Researchers characterized microplastics in wastewater and investigated their interactions with antibiotics, examining how microplastic surfaces adsorb antibiotic compounds and the implications for antibiotic transport and dissemination in wastewater treatment systems.

2025 e_Buah
Article Tier 2

Pharmaceuticals in Water: Risks to Aquatic Life and Remediation Strategies

This review examines how pharmaceutical drugs in waterways threaten aquatic life and potentially human health. The biggest concern is the rise of antibiotic resistance from drugs entering water through household and agricultural waste. While not specifically about microplastics, the topic is connected because microplastics can adsorb and transport pharmaceutical residues through water systems.

2023 Hydrobiology 99 citations
Systematic Review Tier 1

A systematic review of sources, occurrence, behavior and risks of global marine antibiotics

This systematic review of global marine antibiotic contamination found that sulfamethoxazole is the most frequently detected antibiotic in seawater, sediment, and marine organisms, with the highest concentrations along coastal China. Coexisting contaminants like microplastics may enhance antibiotic impacts and drive antibiotic resistance gene development in marine environments.

2025 npj Emerging Contaminants 5 citations
Review Tier 2

Occurrence, Bioaccumulation, Metabolism and Ecotoxicity of Fluoroquinolones in the Aquatic Environment: A Review

This review examines fluoroquinolone antibiotic contamination in waterways across 32 countries, finding widespread pollution especially in developing nations. These antibiotics accumulate in aquatic organisms and move through the food chain, with toxicity varying by species and environmental conditions. The co-occurrence of antibiotics and microplastics in water is a growing concern, as microplastics can absorb and transport these drugs, potentially increasing human exposure.

2023 Toxics 61 citations
Article Tier 2

Impact of wastewater treatment plant effluent discharge on the antibiotic resistome in downstream aquatic environments: a mini review

This review summarizes how wastewater treatment plants release antibiotic-resistant bacteria and resistance genes into rivers and lakes through their treated water. Current treatment processes cannot fully remove these resistance factors, allowing them to spread in downstream water bodies and potentially reach humans through drinking water and the food chain. The review is relevant to microplastics research because microplastics in wastewater can serve as surfaces where resistant bacteria grow and spread.

2023 Frontiers of Environmental Science & Engineering 31 citations
Article Tier 2

The problem of contamination of aquatic ecosystems with antibiotics (a review)

This review examines the contamination of aquatic ecosystems by antibiotics, synthesizing global data on risks associated with antibiotic presence in ocean and freshwater environments, including effects on aquatic organisms and the promotion of antibiotic resistance. The authors assess quantitative and qualitative contamination using bivalves as bioindicators and evaluate the spread of resistance genes through aquatic biocenoses.

2023 Ribogospodarsʹka nauka Ukraïni 3 citations
Article Tier 2

Profiling of Antibiotic Residues in Surface Water of River Yamuna Stretch Passing through Delhi, India

Researchers detected antibiotic residues in the River Yamuna passing through Delhi, with ofloxacin found at the highest concentration (145 ng/mL), and observed significant seasonal and spatial variation linked to hospital discharge, drug manufacturing, and agricultural runoff.

2023 Water 40 citations
Article Tier 2

The occurrence of microplastic in specific organs in commercially caught fishes from coast and estuary area of east China

Researchers studied how polyethylene microplastics interact with the antibiotic ciprofloxacin in aquatic environments and found that the plastic particles can absorb and concentrate the drug on their surface. The adsorption capacity increased with weathering of the plastic, suggesting that aged microplastics in the environment are more effective carriers of pharmaceutical pollutants. The findings raise concerns that microplastics could transport antibiotics through water systems, potentially contributing to antimicrobial resistance.

2018 Journal of Hazardous Materials 453 citations
Article Tier 2

Physicochemical analysis and detection of exceptionally high diclofenac concentration in the pharmaceutical wastewaters collected from the production units of national industrial zone, Rawat, Pakistan

Researchers analyzed wastewater from 14 pharmaceutical factories in Pakistan and found exceptionally high concentrations of the anti-inflammatory drug diclofenac — up to 311,495 micrograms per liter — far exceeding safe limits, and found that even reverse osmosis treatment failed to adequately remove contaminants, pointing to a serious gap in pharmaceutical wastewater management.

2023 Applied Water Science 14 citations
Article Tier 2

Occurrence, fate, and toxicity of emerging contaminants in a diverse ecosystem

This review examined the occurrence, fate, and toxicity of emerging contaminants including microplastics, pharmaceuticals, and endocrine disruptors across diverse ecosystems, tracing their pathways from wastewater treatment systems into natural environments.

2021 Physical Sciences Reviews 7 citations
Article Tier 2

Comparative selective pressure potential of antibiotics in the environment

Researchers developed a life-cycle-based framework to compare the antibiotic resistance selection pressure potential of various antibiotics in the environment, finding that measured environmental concentrations of certain antibiotics exceed predicted thresholds for resistance selection.

2022 Environmental Pollution 34 citations
Article Tier 2

Fluoroquinolones: Fate, effects on the environment and selected removal methods

Researchers review the fate of fluoroquinolone antibiotics — a widely used class of drugs — in water systems, where conventional wastewater treatment fails to fully remove them, creating risks for ecosystems and human health. Advanced removal methods including light-based degradation (photocatalysis), chemical oxidation, and biological breakdown are evaluated for their effectiveness.

2023 Journal of Cleaner Production 83 citations
Article Tier 2

Occurrence, Source Apportionment, and Risk Assessment of Antibiotics in Mangrove Sediments from the Lianzhou Bay, China

Researchers assessed the occurrence and ecological risks of 39 different antibiotics in mangrove sediments from Lianzhou Bay, China. They found antibiotics from multiple classes present at measurable concentrations, with aquaculture and urban discharge identified as primary sources. The study warns that antibiotic contamination in these sensitive coastal ecosystems may contribute to the spread of antimicrobial resistance.

2024 Antibiotics 4 citations
Article Tier 2

Anti-inflammatory drugs analysis in a wastewater sewage treatment plant and surface water in semiarid climate

This Brazilian study analyzed the presence of four common pain and fever medications in a river and at a wastewater treatment plant over multiple seasons. Pharmaceutical pollution of waterways coexists with microplastic contamination, and treatment plants similarly struggle to fully remove both types of emerging pollutants.

2023 Revista Brasileira de Ciências Ambientais 2 citations