Papers

61,005 results
|
Article Tier 2

Chronic and transgenerational effects of silver nanoparticles in freshwater gastropod Lymnaea stagnalis

Researchers tracked the effects of silver nanoparticles — widely used in consumer products like clothing and coatings — across two generations of freshwater snails (Lymnaea stagnalis). They found that parental exposure caused oxidative stress and reduced reproduction, and these harmful effects were passed on to offspring even after transfer to clean water, demonstrating that nanoparticle toxicity can span generations in aquatic organisms.

2022 Chemosphere 20 citations
Article Tier 2

Toxicokinetics and bioaccumulation of silver sulfide nanoparticles in benthic invertebrates in an indoor stream mesocosm

Researchers used an indoor stream mesocosm to compare bioaccumulation of silver sulfide nanoparticles versus dissolved silver nitrate in three freshwater invertebrates, finding that while ionic silver accumulated 1.5–11 times more readily, nanoparticulate silver was still bioavailable, and that single-species lab tests poorly predicted accumulation in the more complex multi-species system.

2023 The Science of The Total Environment 11 citations
Meta Analysis Tier 1

Emerging investigator series: metal nanoparticles in freshwater: transformation, bioavailability and effects on invertebrates

This review and meta-analysis found that silver nanoparticles are toxic to freshwater invertebrates at environmentally relevant concentrations, with toxicity mediated by both dissolved silver ions and nano-specific effects. Environmental transformation processes like aggregation, dissolution, and surface coating alteration significantly modify nanoparticle bioavailability and toxicity. These findings parallel microplastic research, where particle size, surface chemistry, and environmental weathering similarly determine biological impact.

2022 Environmental Science Nano 58 citations
Article Tier 2

Metabolic equilibrium and reproductive resilience: Freshwater gastropods under nanoplastics exposure

Researchers exposed freshwater snails to nanoplastics of two different sizes and found concentration-dependent effects on body condition and bioaccumulation, with larger particles accumulating more in tissues. While carbohydrate and protein reserves remained largely stable, lipid metabolism and mitochondrial function were affected at certain exposures. Despite these metabolic shifts, the snails maintained overall energy balance, suggesting some resilience to nanoplastic stress over the 21-day study period.

2023 Chemosphere 8 citations
Review Tier 2

Bioaccumulation and ecotoxicological impact of micro(nano)plastics in aquatic and land snails: Historical review, current research and emerging trends

This review summarizes the ecotoxicological impacts of micro- and nanoplastics on aquatic and land snail species worldwide. Researchers found evidence of microplastic bioaccumulation in 40 gastropod species, with Asia showing the highest contamination levels, and documented harmful effects including behavioral changes, oxidative stress, and tissue damage. The study highlights that toxicity depends on particle composition, shape, and size, and identifies significant research gaps in understanding how these pollutants affect invertebrate communities.

2022 Journal of Hazardous Materials 60 citations
Article Tier 2

Shape-Dependent Toxicity of Silver Nanoparticles on Freshwater Cnidarians

Researchers investigated how the shape of silver nanoparticles affects their toxicity to freshwater Hydra vulgaris, finding that triangular nanoplates were significantly more toxic than spherical or rod-shaped particles, challenging the assumption that toxicity is shape-independent.

2022 Nanomaterials 32 citations
Article Tier 2

Sensitivity of Hydra vulgaris to Nanosilver for Environmental Applications

Researchers tested a novel citrate and L-cysteine functionalized silver nanoparticle formulation against freshwater Hydra vulgaris, characterizing its environmental safety and finding that the nanoparticles caused dose-dependent toxicity, providing a useful benchmark for assessing nanomaterial risks in aquatic ecosystems.

2022 Toxics 6 citations
Article Tier 2

Combined toxic effects of environmental predominant microplastics and ZnO nanoparticles in freshwater snail Pomaceae paludosa

Researchers assessed the toxic effects of zinc oxide nanoparticles and polypropylene microplastics, both individually and combined, on the freshwater snail Pomeacea paludosa over 28 days. The study found that combined exposure caused more severe oxidative stress, disrupted antioxidant and digestive enzyme activity, and led to tissue damage and DNA damage compared to individual pollutant exposure. Evidence indicates that microplastics interacting with nanoparticles can amplify toxic effects in freshwater organisms.

2023 Environmental Pollution 25 citations
Article Tier 2

In Vivo Metabolic Response upon Exposure to Gold Nanorod Core/Silver Shell Nanostructures: Modulation of Inflammation and Upregulation of Dopamine

Researchers investigated the in vivo metabolic response of organisms exposed to gold nanorod core/silver shell nanostructures, finding that the hybrid nanoparticles induced distinct metabolic perturbations including inflammatory pathway activation and oxidative stress markers. The study advances understanding of silver nanoparticle toxicity mechanisms at the systemic metabolic level.

2020 International Journal of Molecular Sciences 18 citations
Article Tier 2

Building the Bridge From Aquatic Nanotoxicology to Safety by Design Silver Nanoparticles

This review examined the nanotoxicology of silver nanoparticles in aquatic environments, synthesizing findings on their environmental behavior and biological effects to help bridge the gap between hazard assessment and safety-by-design approaches for engineered nanomaterials.

2022 Frontiers in Bioengineering and Biotechnology 26 citations
Article Tier 2

Impacts of Differentially Shaped Silver Nanoparticles with Increasingly Complex Hydrophobic Thiol Surface Coatings in Small-Scale Laboratory Microcosms

Researchers tested how differently shaped silver nanoparticles with various surface coatings affected small ecosystems containing algae, bacteria, crustaceans, and fish embryos. They found that both particle shape and surface chemistry influenced how toxic the nanoparticles were to different organisms. The study suggests that the physical characteristics of engineered nanoparticles play an important role in determining their environmental impact.

2024 Nanomaterials 5 citations
Article Tier 2

Microplastic fibers influence Ag toxicity and bioaccumulation in Eisenia andrei but not in Enchytraeus crypticus

Researchers exposed two soil invertebrates — Eisenia andrei earthworms and Enchytraeus crypticus enchytraeids — to silver nanoparticles combined with microplastic fibers, finding that fibers increased silver accumulation and toxicity in earthworms but not in enchytraeids, revealing species-specific interactions between these co-contaminants.

2021 Ecotoxicology 25 citations
Article Tier 2

Assessment of oxidative stress, neurotoxicity, genotoxicity and prey-predator interactions in freshwater snails exposed to microplastics

This conference abstract investigates oxidative stress, nerve damage, DNA damage, and changes in predator-prey behavior in freshwater snails exposed to microplastics, pointing to a broad range of harmful biological effects. Understanding these impacts in aquatic invertebrates matters because they occupy important ecological roles and their exposure to microplastics can have cascading effects through food webs.

2023 Endocrine Abstracts
Article Tier 2

Microplastics alleviate phytotoxicity of silver nanoparticles in Ottelia cordata submerged leaves

Researchers investigated the combined effects of silver nanoparticles and polystyrene microplastics on the aquatic plant Ottelia cordata, finding that microplastics actually alleviated the phytotoxicity of silver nanoparticles by reducing their bioavailability. The results highlight complex antagonistic interactions between co-occurring aquatic contaminants.

2025 Aquatic Toxicology
Article Tier 2

Acute Adverse Effects of Metallic Nanomaterials on Cardiac and Behavioral Changes in Daphnia Magna

This study tested the acute toxicity of titanium dioxide and silver nanoparticles on the water flea Daphnia magna, finding that both types slowed heart rate and swimming speed. While focused on metallic nanoparticles rather than microplastics, the study contributes to understanding how nano-scale particles affect aquatic organisms.

2021 Research Square (Research Square) 1 citations
Article Tier 2

Impact of progressively cumulative exposure of AgNPs on earthworms (Eisenia fetida) and implication for eco-toxicological risk assessment

Researchers compared earthworm responses to silver nanoparticles delivered either all at once or progressively increasing doses over 28 days, finding that gradual exposure caused less tissue damage, lower bioaccumulation, and activated more detoxification pathways — suggesting that standard one-step laboratory toxicity tests may overestimate real-world ecological risk.

2023 Chemosphere 18 citations
Article Tier 2

Data acquired in laboratory experiments conducted to characterize Ag bioaccumulation kinetics in Daphnia magna after exposures to polystyrene microplastics and Ag nanoparticles

Researchers assessed how the presence of polystyrene microplastics affects the bioaccumulation of silver nanoparticles in the filter-feeding zooplankton Daphnia magna. The study provides laboratory data on silver uptake kinetics at environmentally relevant concentrations, contributing to understanding how microplastics may interact with other contaminants to alter their biological availability to aquatic organisms.

2026 USGS DOI Tool Production Environment
Article Tier 2

Ingestion and toxicity of microplastics in the freshwater gastropod Lymnaea stagnalis: No microplastic-induced effects alone or in combination with copper

Scientists exposed the freshwater snail Lymnaea stagnalis to polystyrene microplastics alone and combined with copper, finding that the snails ingested and excreted microplastics but that neither microplastics alone nor in combination with copper caused measurable toxic effects.

2020 Chemosphere 87 citations
Article Tier 2

Biotoxicity of silver nanoparticles complicated by the co-existence of micro-/nano-plastics

Researchers gave mice a 90-day oral exposure to silver nanoparticles combined with either micro- or nano-sized polystyrene plastics and found that the plastic particles worsened the toxicity of the silver. Evidence indicates that nanoplastics may be particularly concerning because their smaller size allows them to cross the blood-brain barrier and cause neuronal damage.

2024 Food and Chemical Toxicology 7 citations
Article Tier 2

Acute toxicity of nanoplastics on Daphnia and Gammarus neonates: Effects of surface charge, heteroaggregation, and water properties

Researchers examined nanoplastic toxicity on crustacean neonates and found that smaller particles (20-40 nm) were more toxic, with surface charge and aggregation behavior being the primary factors influencing toxicity depending on species and water conditions.

2022 The Science of The Total Environment 22 citations
Article Tier 2

Metal sorption onto nanoscale plastic debris and trojan horse effects in Daphnia magna: Role of dissolved organic matter

Researchers tested whether nanoscale plastic particles act as a "Trojan horse" by carrying toxic silver ions into water fleas (Daphnia magna), finding that the plastic-silver combination was indeed toxic even when neither substance alone caused harm — but dissolved organic matter (naturally present in rivers and lakes) largely blocked this effect. This suggests the Trojan horse risk from nanoplastics may be lower in natural freshwater environments than lab conditions imply.

2020 Water Research 92 citations
Article Tier 2

Toxicokinetics and toxicodynamics of plastic and metallic nanoparticles: A comparative study in shrimp

Researchers compared the toxicokinetics and toxicodynamics of plastic and metallic nanoparticles in shrimp, finding distinct differences in uptake, distribution, and toxic mechanisms that highlight the need for nanoplastic-specific risk assessment frameworks.

2022 Environmental Pollution 27 citations
Article Tier 2

Toxic effects on ciliates under nano-/micro-plastics coexist with silver nanoparticles

Researchers tested the combined effects of different-sized plastic particles with silver nanoparticles on marine microorganisms and found that the mixture was more toxic than either pollutant alone. Smaller nanoplastics combined with silver nanoparticles caused the most severe damage, disrupting energy and fat metabolism and causing DNA and protein damage. This study shows how microplastics can amplify the toxicity of other environmental pollutants in marine food chains.

2023 Journal of Hazardous Materials 32 citations
Article Tier 2

Effects of natural organic matter on the joint toxicity and accumulation of Cu nanoparticles and ZnO nanoparticles in Daphnia magna

Researchers tested how copper and zinc oxide nanoparticle mixtures affect the water flea Daphnia magna in the presence and absence of natural organic matter, finding additive-to-synergistic joint toxicity and showing that natural organic matter shifts the dominant toxic species toward dissolved zinc ions while increasing nanoparticle accumulation in the organism's body.

2021 Environmental Pollution 27 citations