Papers

61,005 results
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Article Tier 2

Micro and Nano-plastic particles: What are they and do they effect cardiovascular health?

This review examines the cardiovascular health effects of micro- and nanoplastics, summarizing evidence that these particles have been detected in human tissues including arterial plaques and may promote endothelial dysfunction and inflammation. The authors call for further clinical and epidemiological research into cardiac risk.

2024 Nepal Journal of Epidemiology 1 citations
Article Tier 2

Emerging cardiovascular risks of micro- and nanoplastics: toxic effects and mechanistic pathways

Tiny plastic particles called micro- and nanoplastics are getting into our bodies through food, air, and skin contact, and researchers have found them building up in people's hearts and blood vessels. This review of existing studies shows these plastic bits may contribute to heart disease by causing inflammation and damaging cells in the cardiovascular system. While more research is needed, this suggests that plastic pollution isn't just an environmental problem—it could be directly harming our heart health.

2026 Particle and Fibre Toxicology
Article Tier 2

Microplastics and nanoplastics: emerging threats to cardiovascular health – a comprehensive review

This comprehensive review examines the emerging evidence linking microplastic and nanoplastic exposure to cardiovascular health problems. The evidence suggests that plastic particles may contribute to heart and blood vessel disease, though more research is needed to fully understand the long-term effects. The review highlights the urgent need for further studies on how chronic exposure to these tiny particles affects the cardiovascular system.

2024 Annals of Medicine and Surgery 13 citations
Article Tier 2

Evidence, Mechanisms, and Clinical Implications of Microplastics and Nanoplastics As Emerging Cardiovascular Risk Factors: A Narrative Review

This review examines growing evidence that micro- and nanoplastics may contribute to cardiovascular health risks, with researchers having found these particles in human artery plaques and blood clots. Evidence indicates that the particles can enter the bloodstream, trigger inflammation, damage blood vessel walls, and potentially increase the risk of heart attacks and strokes. While the evidence is not yet conclusive, the study highlights an emerging area of concern that warrants further investigation into how everyday plastic exposure may affect heart and blood vessel health.

2025 Cureus 2 citations
Article Tier 2

Micro- and nanoplastics: A new cardiovascular risk factor?

This review examines the growing evidence that micro- and nanoplastics may pose risks to the heart and blood vessels. Studies in animals and cell cultures show that these tiny plastic particles can enter the bloodstream, trigger inflammation, promote blood clotting, and damage blood vessel walls. While human data is still limited, the review suggests that micro- and nanoplastic exposure should be considered a potential new risk factor for cardiovascular disease.

2022 Environment International 227 citations
Article Tier 2

Microplastics. a New Risk Factor for Atherosclerotic Cardiovascular Disease

This paper reviews emerging evidence linking microplastic exposure to atherosclerotic cardiovascular disease, noting that MPs have been detected in arterial plaques and human tissues and may contribute to cardiovascular risk through inflammation, oxidative stress, and endothelial disruption.

2025 American Journal of Preventive Cardiology
Article Tier 2

Microplastics, Nanoplastics and Heart Contamination: The Hidden Threat

This review examines growing evidence that micro- and nanoplastics can accumulate in human cardiovascular tissues, including blood, heart muscle, and arterial plaques. Researchers found that these particles may contribute to heart and blood vessel problems through inflammation, oxidative stress, blood clotting, and direct tissue injury. The study identifies plastic particles as a potential new environmental risk factor for cardiovascular health.

2025 Journal of Clinical Medicine 2 citations
Article Tier 2

Micro-nanoplastics and cardiovascular diseases: evidence and perspectives

Growing evidence suggests that micro- and nanoplastic particles may be a previously unrecognized risk factor for heart disease, as they have been detected in atherosclerotic plaques, heart tissue, and blood clots in humans. Lab studies show these particles can trigger oxidative stress, promote blood clotting, and cause inflammation in blood vessel cells, and their presence in artery plaques has been linked to higher rates of cardiovascular events.

2024 European Heart Journal 88 citations
Article Tier 2

Microplastics: A Modifiable Cardiac Risk Factor

This review examines the emerging evidence linking microplastic exposure to cardiovascular disease risk factors, including oxidative stress, inflammation, endothelial dysfunction, and thrombosis. The study highlights that micro- and nanoplastics have been identified in coronary artery plaque, suggesting that microplastic exposure may represent a modifiable but currently underrecognized cardiac risk factor.

2026 Cardiology in Review
Article Tier 2

Impact of microplastics and nanoplastics on cardiovascular health

This review examines the emerging evidence on how microplastics and nanoplastics may affect cardiovascular health. The study discusses clinical evidence suggesting that these particles can accumulate in the cardiovascular system and highlights possible molecular mechanisms including inflammation and oxidative stress, while noting that current evidence linking microplastics to cardiovascular disease remains largely correlative.

2026 Trends in Cardiovascular Medicine
Article Tier 2

Microplastics and Nanoplastics

Researchers examined the connection between microplastics and nanoplastics and cardiovascular disease, a group of conditions affecting the heart and blood vessels. Growing evidence suggests these tiny plastic particles may pose risks to heart and vascular health.

2024 JACC Advances 3 citations
Article Tier 2

Nanoplastics as emerging cardiovascular hazards: a narrative review of current evidence

This review examines the emerging evidence that nanoplastics may pose risks to cardiovascular health. Researchers summarized studies showing that nanoplastics can enter the bloodstream through ingestion, inhalation, and skin contact, potentially causing inflammation and oxidative damage to blood vessels and heart tissue. The study suggests that nanoplastic exposure represents an understudied but potentially significant environmental risk factor for heart and vascular problems.

2024 The Egyptian Journal of Internal Medicine 7 citations
Article Tier 2

An Emerging Role of Micro- and Nanoplastics in Vascular Diseases

This review summarizes emerging research on how micro- and nanoplastics may contribute to vascular diseases, which are the leading cause of death worldwide. Studies suggest that these tiny plastic particles can damage blood vessel walls, promote inflammation, and worsen conditions like atherosclerosis. While more research is needed, the evidence points to microplastic exposure as a potential new risk factor for heart and blood vessel diseases.

2024 Life 15 citations
Article Tier 2

Microplastics and Cardiovascular Disease: Should Clinicians Be Paying Attention?

This clinical review summarizes evidence for microplastics as a cardiovascular risk factor, noting that they have been detected in human cardiovascular tissues and that in vitro and animal studies link them to oxidative stress, endothelial dysfunction, and platelet disruption, while cautioning that human evidence remains associative.

2025 Current Cardiology Reports
Article Tier 2

Tiny trouble: microplastics, nanoplastics, and their heartfelt impact on cardiovascular health

This review summarizes growing evidence that microplastics and nanoplastics have been found in human heart tissue, arterial plaques, and blood, and may increase the risk of cardiovascular disease. Lab studies show these particles can damage blood vessel walls, disrupt cholesterol processing, trigger inflammation, and promote blood clot formation, raising serious concerns about heart health.

2025 Cardiovascular Research 10 citations
Article Tier 2

Micro- and nanoplastics are elevated in femoral atherosclerotic plaques compared with undiseased arteries

Researchers found significantly higher concentrations of microplastics and nanoplastics in diseased arterial plaques from human patients with limb-threatening vascular disease compared to healthy arteries, adding to growing evidence that these particles accumulate in cardiovascular tissue and may play a role in artery disease.

2025 JVS Vascular Science 3 citations
Article Tier 2

Standardizing methodologies to study microplastics and nanoplastics in cardiovascular diseases

Researchers highlighted that microplastics and nanoplastics are emerging as new risk factors for cardiovascular health, with evidence indicating they can impair blood vessel cell functions and worsen artery-clogging processes. However, the widely varying concentrations of these particles found in heart and vascular tissues point to a lack of standardized research methods. The study calls for unified approaches to better understand how plastic particles affect the cardiovascular system.

2024 Trends in Endocrinology and Metabolism 6 citations
Article Tier 2

Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review

Researchers reviewed evidence from animal and human studies on how micro- and nanoplastics (MNPs) affect the heart and blood vessels, finding that MNPs can damage the inner lining of blood vessels, promote plaque buildup, and interfere with blood clotting — all of which raise the risk of heart disease. The review calls for more research to understand how much MNP accumulation occurs in the human cardiovascular system and what it means for long-term cardiac health.

2025 Journal of Exposure Science & Environmental Epidemiology 16 citations
Article Tier 2

Weekly Journal Scan: Plastic particles in carotid plaques—inactive debris or predictors of cardiovascular events?

This journal scan summarizes a prospective multicenter study that detected microplastics and nanoplastics in excised carotid artery plaques and found that higher plaque burden of plastic particles was associated with increased risk of cardiovascular events. The findings raise the possibility that microplastics in arterial tissue are not inert but biologically active.

2024 European Heart Journal
Article Tier 2

Effects of microplastics and nanoplastics on the kidney and cardiovascular system

This review summarizes evidence that microplastics and nanoplastics found in human hearts, kidneys, blood, and urine can cause oxidative stress, inflammation, cell death, and metabolic disruption. Kidney dialysis patients may face especially high exposure, and clinical evidence suggests particulate plastic exposure is a risk factor for cardiovascular disease.

2025 Nature Reviews Nephrology 24 citations
Article Tier 2

Microplastics and Nanoplastics in Atheromas and Cardiovascular Events

This landmark clinical study found that patients with micro- and nanoplastics detected in their carotid artery plaque had a significantly higher risk of heart attack, stroke, or death over a 34-month follow-up period compared to those without detectable plastics. This is one of the first studies to directly link microplastic presence in human blood vessels to worse cardiovascular outcomes. The findings suggest that plastic accumulation in arteries may be an important and previously unrecognized risk factor for heart disease.

2024 New England Journal of Medicine 843 citations
Article Tier 2

Plastic particle impacts on the cardiovascular system and angiogenesis potential

This review examines emerging evidence on how micro- and nanoplastic particles may affect the cardiovascular system. Researchers found that these particles can potentially cross biological barriers and reach cardiovascular tissues, where they may interact with cellular components and amplify the toxicity of other co-occurring contaminants.

2024 Molecular and Cellular Biochemistry 3 citations
Systematic Review Tier 1

Micro- and nanoplastics in the cardiovascular system: current evidence, research gaps: a systematic review

This systematic review examined how microplastics and nanoplastics affect the heart and blood vessels. Studies in both animals and human tissue found that these particles can cause blood vessel inflammation, disrupt heart function, and were even linked to higher rates of heart attack and stroke in people with plastic particles in their arteries.

2025 MEDICAL SCIENCE PULSE