Papers

61,005 results
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Article Tier 2

Microplastic Exposure Across Trophic Levels: Effects on the Host Microbiota of Freshwater Organisms

Researchers investigated how microplastic exposure affects the gut bacteria communities of freshwater organisms including fish, invertebrates, and crustaceans. Microplastics—particularly when combined with pesticides—altered gut microbiota composition, which could impair digestion, immunity, and overall health of freshwater species.

2021 1 citations
Article Tier 2

The effects of exposure to microplastics and pollutants on the arthropod microbiome

This thesis investigated how microplastics and other pollutants (pesticides, detergents, metals) affect the gut microbiome of freshwater invertebrates. Disruption of the host-microbiome relationship by microplastics could impair immune function and overall health in aquatic organisms that form important parts of the food web.

2021 Digital comprehensive summaries of Uppsala dissertations from the Faculty of Science and Technology
Article Tier 2

Effect of emerging pollutants on the gut microbiota of freshwater animals: Focusing on microplastics and pesticides

This review examines how microplastics and pesticides, two pollutants commonly found together in freshwater, each disrupt the gut bacteria of fish and other aquatic animals, and their combined presence can make the effects worse. Changes in gut bacteria caused by these pollutants can impair metabolism, immunity, and overall health of aquatic organisms, with potential consequences for the food chain.

2024 The Science of The Total Environment 46 citations
Article Tier 2

Microplastic exposure across trophic levels: effects on the host–microbiota of freshwater organisms

Researchers examined how microplastic exposure across trophic levels affects the gut microbiota of freshwater organisms, finding that microplastics alter microbial community composition and that effects can transfer through food web interactions.

2022 Environmental Microbiome 29 citations
Article Tier 2

From plankton to fish: The multifaceted threat of microplastics in freshwater environments

This review summarizes how microplastics harm freshwater organisms from tiny plankton to fish through oxidative stress, inflammation, DNA damage, gut microbiome disruption, and metabolic disorders. Microplastics often combine with other pollutants in water, making their toxic effects even worse. Since freshwater systems are a major pathway for microplastics entering oceans and our food supply, understanding these effects is critical for protecting both ecosystems and human health.

2025 Aquatic Toxicology 17 citations
Article Tier 2

Single and combined effects of microplastics, pyrethroid and food resources on the life-history traits and microbiome of Chironomus riparius

Researchers exposed Chironomus riparius larvae to microplastics alone and combined with a pyrethroid pesticide under varying food conditions, finding that combined stress altered life-history traits and shifted the gut microbiome composition, with food availability modulating the severity of effects.

2021 Environmental Pollution 47 citations
Article Tier 2

Effects of microplastics and phenanthrene on gut microbiome and metabolome alterations in the marine medaka Oryzias melastigma

Researchers exposed marine medaka fish to microplastics combined with phenanthrene, a common organic pollutant, and found that the combination disrupted gut bacteria and metabolism more than either substance alone. Specific gut bacterial communities shifted in response to the combined exposure, leading to changes in important metabolic processes. This study underscores that microplastics in the ocean don't act alone; they interact with other pollutants to amplify harm to aquatic organisms and potentially to the humans who consume seafood.

2023 Journal of Hazardous Materials 33 citations
Article Tier 2

Effects of environmental factors on host-microbiota interactions in the guts of aquatic organisms: A review

This review synthesizes how environmental stressors — including microplastics, heavy metals, photoperiod, and aquaculture feed additives — alter gut microbiota in fish and aquatic invertebrates, identifying common patterns of microbial disruption and compromised gut barrier integrity.

2025 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 2 citations
Article Tier 2

Plastics in our water: Fish microbiomes at risk?

This review examined how microplastics and leached plasticizers affect the gut microbiomes of freshwater and marine fish, summarizing evidence for dysbiosis and reduced microbial diversity and discussing potential consequences for fish immunity, metabolism, and environmental fitness.

2021 Comparative Biochemistry and Physiology Part D Genomics and Proteomics 25 citations
Article Tier 2

Ecological risks of combination of multiple pollutants at environmentally relevant concentrations: Insights from the changes in life history traits, gut microbiota, and transcriptomic responses in Daphnia magna

Researchers exposed Daphnia magna to a combination of 11 pollutants including microplastics, antibiotics, and heavy metals at environmentally relevant ng/L–μg/L concentrations and found significant reductions in heart rate, reproduction, and lifespan, plus gut microbiota and transcriptomic changes — effects that single-pollutant studies would not predict.

2025 Resources Environment and Sustainability
Article Tier 2

Gut microbiota of aquatic organisms: A key endpoint for ecotoxicological studies

This review examines how environmental contaminants including microplastics, pesticides, heavy metals, and pharmaceuticals affect the gut microbiota of aquatic organisms. Researchers highlight that changes in gut bacterial communities can serve as sensitive indicators of pollution exposure and may have downstream effects on host fitness. The study calls for improved methodologies to better link contaminant-induced shifts in gut microbiota to measurable health outcomes in aquatic species.

2019 Environmental Pollution 261 citations
Article Tier 2

Impact of polypropylene microplastics and chemical pollutants on European sea bass (Dicentrarchus labrax) gut microbiota and health

Researchers investigated how polypropylene microplastics, alone and combined with chemical pollutants, affect the gut health and microbiome of European sea bass. They found that microplastic ingestion altered the gut microbial community composition and that combined exposure with pollutants amplified the harmful effects. The study suggests that microplastics may serve as carriers for toxic chemicals, compounding their impact on fish health and potentially affecting seafood safety.

2021 The Science of The Total Environment 119 citations
Article Tier 2

Micro- and nanoplastics effects in a multiple stressed marine environment

Researchers examined how micro- and nanoplastics interact with other environmental stressors in marine settings, finding that realistic multi-stressor scenarios can amplify or modify plastic toxicity in ways single-exposure studies miss.

2022 Journal of Hazardous Materials Advances 21 citations
Article Tier 2

Gut microbiota related response of Oryzias melastigma to combined exposure of polystyrene microplastics and tetracycline

Researchers exposed estuarine fish to polystyrene microplastics and the antibiotic tetracycline, both alone and in combination, for four weeks. The combined exposure caused more severe disruption to gut bacteria and liver tissue than either pollutant alone, with microplastics appearing to worsen the effects of tetracycline. The study suggests that the co-occurrence of microplastics and antibiotics in coastal waters may pose greater ecological risks than either contaminant by itself.

2023 The Science of The Total Environment 18 citations
Article Tier 2

Interactive Threats: Multi-stress Systems in Aquatic Environments

Researchers examined how aquatic organisms face multiple simultaneous stressors — including plastic pollution, climate change, altered pH, and habitat loss — finding that the combined interactive effects of these threats are poorly understood yet critical to developing effective conservation and management strategies.

2023 1 citations
Article Tier 2

Combined Effects of Polystyrene Nanoplastics and Enrofloxacin on the Life Histories and Gut Microbiota of Daphnia magna

Researchers exposed Daphnia magna to polystyrene nanoplastics and the antibiotic enrofloxacin alone and in combination, measuring life history traits and gut microbiota responses. Both stressors individually reduced survival and reproduction, and combined exposure altered the taxonomic composition and metabolic function of gut microbiota more than either contaminant alone.

2022 Water 19 citations
Article Tier 2

Freshwater systems in the Anthropocene: why we need to evaluate microplastics in the context of multiple stressors

Real-world organisms are exposed to microplastics alongside many other environmental stressors — temperature change, chemical pollutants, habitat degradation — yet most lab studies test microplastics in isolation. This review argues that ecotoxicology needs to adopt a multi-stressor approach to truly understand how microplastics affect freshwater life at every level, from individual cells to whole ecosystems. Without this broader context, risk assessments will consistently underestimate the actual harm microplastics cause in nature.

2024 F1000Research 2 citations
Article Tier 2

Microplastics as an aquatic pollutant affect gut microbiota within aquatic animals

This review examined how microplastics affect the gut microbiota of aquatic animals, analyzing the roles of plastic-associated chemicals and biofilms in disrupting microbial communities from ingestion through physiological impacts.

2021 Journal of Hazardous Materials 109 citations
Article Tier 2

A fishy tale: the impact of multiple stressors on host behaviour, physiology, and susceptibility to infectious disease

This PhD thesis studied how multiple stressors — including microplastics, chemicals, and disease — combine to affect fish behavior, physiology, and vulnerability to infections in freshwater habitats. Freshwater fish face converging threats that are driving population declines faster than any other vertebrate group.

2020
Article Tier 2

Effects of microplastics on Daphnia-associated microbiomes in situ and in vitro

This study investigated how microplastic exposure alters the microbiome associated with Daphnia in freshwater, finding shifts in bacterial community composition that may affect host health and ecological function. The results suggest that microplastics can indirectly harm zooplankton by disrupting their microbial symbionts.

2024
Article Tier 2

Toxicological effects of microplastics and phenanthrene to zebrafish (Danio rerio)

Researchers exposed zebrafish to polystyrene microplastics, the pollutant phenanthrene, and a combination of both to assess their toxicity over 24 days. They found that co-exposure amplified oxidative stress, suppressed immune gene expression, and significantly disrupted the gut microbiome compared to either contaminant alone. The study suggests that microplastics can worsen the toxic effects of organic pollutants in aquatic organisms by altering how chemicals accumulate and interact in the body.

2020 The Science of The Total Environment 190 citations
Article Tier 2

Co-exposure to microplastics and tire particles exacerbates oxidative stress and gut microbiome dysbiosis in zebrafish (Danio rerio)

Researchers exposed zebrafish for 21 days to environmentally relevant mixtures of microplastics and tire particles and found that combined exposure caused more severe oxidative stress and gut microbiome disruption than either pollutant alone. Particle accumulation occurred mainly in the gut with secondary deposition in the liver, and the most pronounced tissue damage was observed under the highest combined exposure. Gut microbiota analysis revealed significant shifts in community structure, including reduced beneficial bacteria and increased pollutant-tolerant species.

2026 Environmental Research
Article Tier 2

The combined effects of polypropylene microplastics and sulfonamide antibiotics on the gut-liver axis of Gymnocypris przewalskii

A multi-omics study examined combined exposure of Gymnocypris przewalskii fish from Qinghai Lake to polypropylene microplastics and sulfonamide antibiotics, finding that co-exposure disrupted metabolic pathways and immune responses more severely than either contaminant alone.

2025 Aquatic Toxicology
Article Tier 2

Microplastic Exposure Across Trophic Levels: Effects on the Host-microbiota of Freshwater Organisms

Researchers found that exposure to 1 µm microplastic beads and the pesticide deltamethrin caused carry-over reductions in microbiome diversity and abundance across a three-level freshwater food chain of daphnids, damselfly larvae, and dragonfly larvae.

2022 Research Square (Research Square) 2 citations