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20 resultsShowing papers similar to Contaminants of emerging concern in the fetal environment
ClearMaternal-fetal implications of exposure to phthalates and nanoplastics during pregnancy in rats
Researchers studied the maternal-fetal implications of exposure to phthalates and PET nanoplastics during rat pregnancy, examining effects on placental function and fetal development. The study investigates how these endocrine-disrupting compounds accumulate in gestating animals and tests the hypothesis that adverse in utero conditions from plastic chemical exposure affect offspring development.
Microplastics in the Perinatal Period: Emerging Evidence on Maternal Exposure, Placental Transfer, and Fetal Health Outcomes
This review summarizes emerging evidence that microplastics can cross the placenta and reach developing babies, having been detected in maternal blood, placental tissue, amniotic fluid, cord blood, and breast milk. The tiny plastic particles may damage the placenta, disrupt hormones, alter immune responses, and potentially affect fetal growth and brain development. While more research is needed, the findings raise serious concerns about microplastic exposure during pregnancy and its implications for infant health.
Placental Exposure to Nanoplastics Threatening the Maternal and Fetal Health
This review examines how nanoplastics reaching the placenta threaten maternal and fetal health, summarizing evidence from animal and in vitro studies showing that placental nanoplastic accumulation disrupts nutrient transport, immune function, and fetal development.
Assessing microplastics as a novel threat to maternal-fetal health: Placental barrier penetration and fetal developmental consequences
This review addressed how microplastics cross the placental barrier and affect fetal development, covering cellular responses in placental tissue, animal model findings, and limited human study data. The authors concluded that transplacental microplastic transfer is a plausible mechanism for intergenerational health effects.
Year 116 of the plastic age: a Pandora’s box as a time bomb for pregnancy? Review of clinical and fundamental data on prenatal exposure to plastics
This review examined evidence for micro- and nanoplastic presence in the human placenta and assessed implications for pregnancy outcomes, synthesizing in vitro, ex vivo, and epidemiological data. Multiple plastic types were detected in placental tissue from the basal plate to fetal membranes, and the authors raised concerns about placental dysfunction and fetal developmental risk.
Microplastics exposure: implications for human fertility, pregnancy and child health
This review examines growing evidence that microplastics accumulate in the human placenta and may affect pregnancy outcomes and child development. Given that exposure during pregnancy can program lifelong health in offspring, the presence of these tiny plastic particles in reproductive tissues raises important concerns about fertility, pregnancy complications, and children's health.
Pregnancy in the Era of the Environmental Crisis: Plastic and Pollution
This review examined the effects of plastic pollution and other environmental contaminants on pregnancy outcomes, arguing that the ongoing environmental crisis poses growing risks to fetal development. The authors called for greater expert focus on educating women about reducing exposure to plastics and pollutants during pregnancy.
Impact of Microplastics on Pregnancy and Fetal Development: A Systematic Review
A systematic review of 12 studies confirmed the presence of microplastics ranging from 2.1 to 100 micrometers in human placentas and fetal tissue. Microplastic levels correlated with reduced birthweight, affected gestational age, diminished microbiome diversity, and impaired fetal growth and development, with lifestyle choices influencing placental microplastic burden.
Endocrine-Disrupting Chemicals and the Offsprings: Prenatal Exposure
This review examines prenatal exposure to endocrine-disrupting chemicals, synthesizing evidence from international regulatory agencies and research groups on how maternal environmental chemical exposure affects fetal development and offspring health outcomes.
Fetus Exposure to Drugs and Chemicals: A Holistic Overview on the Assessment of Their Transport and Metabolism across the Human Placental Barrier
This review examines the various experimental methods used to study how drugs and chemicals cross the placental barrier and reach the developing fetus. Understanding how contaminants including microplastics can pass from mother to baby is essential for protecting fetal health and developing safer guidelines for chemical exposure during pregnancy.
Microplastics: A threat to Fetoplacental unit and Reproductive systems
This review examines how micro- and nanoplastics may harm the placenta and reproductive system, particularly during pregnancy. The authors highlight that these tiny plastic particles have been found in placental tissue and may interfere with fetal development, though they note that much more research is needed to understand the full risks to mothers and babies.
The Impact of Maternal Nanoplastic and Microplastic Particle Exposure on Mammal’s Offspring
This review summarizes research on how a mother's exposure to nanoplastics and microplastics during pregnancy can affect her developing baby. Studies show that these tiny plastic particles can cross the placenta and reach the fetus, potentially harming brain development, the reproductive system, metabolism, and the immune system of offspring. The review calls for more research using realistic exposure levels to better understand the risks of prenatal microplastic exposure to human babies.
Examining the hidden dangers: Understanding how microplastics affect pregnancy
This review examines how microplastics may affect pregnancy, covering how these tiny particles enter the body through food, water, and air, and can potentially cross the placenta to reach the developing fetus. Early research suggests that the timing of exposure during pregnancy may influence the level of risk to both mother and baby. While the field is still young, the findings highlight pregnancy as a particularly vulnerable period for microplastic exposure.
Editorial: Maternal-fetal interface: new insight in placenta research, volume II
This editorial compiles research showing that microplastics have been detected in human placental tissue and induce cytotoxicity, oxidative stress, and metabolic disturbances in placental explants. The collection of studies underscores that environmental contaminants including microplastics represent a significant and urgent threat to placental function and fetal development.
The impact of environmental factors and contaminants on thyroid function and disease from fetal to adult life: current evidence and future directions
This review examines how environmental factors including pollution, endocrine-disrupting chemicals like bisphenols and phthalates, and microplastics may be contributing to the rising rates of thyroid disorders and thyroid cancer over the past decade. These contaminants can mimic or block thyroid hormones, disrupting the gland's ability to regulate metabolism and development from fetal life through adulthood.
Microplastics as an emerging threat to human health: Challenges and advancements in their detection
This review examined microplastics as an emerging threat to human health, highlighting their endocrine-disrupting properties, ability to accumulate pollutants, and the analytical challenges in accurately detecting and characterizing them across environmental and biological samples.
The Invisible Threat: Microplastics in Human Blood and Placenta
This review summarized current evidence on microplastic detection in human blood and placenta, discussing what is known about how these particles enter the bloodstream and reach fetal tissue. The authors highlight the potential implications for maternal and fetal health.
Microplastics and the Placenta: A Call to Action for Perinatal Research
This commentary reviewed evidence that microplastics have been detected in human placental and neural tissues and discussed their potential effects on fetal development, including systemic inflammation, neurotoxicity, and endocrine disruption. The authors called for multidisciplinary perinatal research to understand and mitigate microplastic exposure during pregnancy.
Micro- and nanoplastics: Emerging environmental threats to the Developmental Origins of Health and Disease
This review examines how micro- and nanoplastic exposure may contribute to chronic health conditions through the lens of developmental origins of health and disease. Evidence suggests that microplastics accumulate in human metabolic and reproductive tissues and may induce physiological and epigenetic changes that could potentially be inherited by future generations, though research into these mechanisms is still in early stages.
Impact of prenatal micro/nanoplastics exposure on intrauterine development and growth: a systematic review
This systematic review examines how exposure to micro- and nanoplastics during pregnancy may affect fetal development and growth. The research gathered evidence showing that tiny plastic particles can reach the placenta and potentially disrupt normal intrauterine development. While more research is needed, these findings raise important questions about protecting pregnant women from microplastic exposure through food, water, and air.