Papers

20 results
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Article Tier 2

Transcriptome Analysis to Study the Molecular Response in the Gill and Hepatopancreas Tissues of Macrobrachium nipponense to Salinity Acclimation

Researchers used Illumina RNA sequencing to perform transcriptome analyses of gill and hepatopancreas tissues from the freshwater prawn Macrobrachium nipponense exposed to three salinity levels. They identified differentially expressed genes related to ion transport, oxidative phosphorylation, and glycometabolism, and confirmed carbonic anhydrase as a key regulator of osmotic adaptation through in situ hybridization.

2022 Frontiers in Physiology 17 citations
Article Tier 2

Two genes related to reproductive development in the juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Nanoplastic exposure altered the expression of two genes involved in reproductive development in juvenile freshwater prawns (Macrobrachium nipponense), suggesting that nanoplastics may disrupt reproductive pathways in crustaceans at low concentrations.

2021 Chemosphere 17 citations
Article Tier 2

Metabonomic Analysis of Macrobrachium rosenbergii with Iron Prawn Syndrome (IPS)

Researchers performed metabonomic and RNA-seq analyses of freshwater prawns (Macrobrachium rosenbergii) affected by Iron Prawn Syndrome, identifying hundreds of differentially expressed proteins and key metabolic pathway disruptions that shed light on the molecular basis of this disease.

2023 Fishes 1 citations
Article Tier 2

Two genes related to apoptosis in the hepatopancreas of juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Researchers identified and characterized two apoptosis-related genes in juvenile prawns exposed to polystyrene nanoplastics, finding that nanoplastic exposure induced significant apoptotic responses in hepatopancreas tissue in a concentration-dependent manner.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Transcriptome Analysis Revealed the Early Heat Stress Response in the Brain of Chinese Tongue Sole (Cynoglossus semilaevis)

Researchers used transcriptome analysis to study how the brains of Chinese tongue sole fish respond to short-term heat stress. They identified distinct gene expression patterns in male and female fish, with key pathways related to cortisol production, immune signaling, and stress-response genes like heat shock proteins. The study provides new insights into the sex-specific brain mechanisms fish use to cope with temperature changes.

2023 Animals 12 citations
Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

[Physiological and Ecological Response Characteristics and Transcriptomic Change Characteristics of Rice (Oryza sativa)Under Different Microplastic Stresses].

Researchers used transcriptomic analysis to characterize physiological and ecological response characteristics of an aquatic organism exposed to microplastic stress, identifying gene expression changes in pathways related to immune function, oxidative stress, and energy metabolism.

2025 PubMed
Article Tier 2

Effects of nanoplastics on antioxidant and immune enzyme activities and related gene expression in juvenile Macrobrachium nipponense

Researchers explored the effects of nanoplastics on survival, antioxidant activity, immune enzyme activity, and gene expression in juvenile oriental river prawns. The study found that increasing nanoplastic concentrations suppressed antioxidant and immune enzyme activities while altering related gene expression levels, indicating that nanoplastic exposure can compromise the defense systems of freshwater crustaceans.

2020 Journal of Hazardous Materials 195 citations
Article Tier 2

Transcriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni)

Researchers exposed piebald naked carp to copper — a common water pollutant — and found it significantly disrupted gene activity in the gills and liver, particularly genes involved in building proteins, suggesting that fish respond to metal-induced stress by broadly slowing down protein production as a protective mechanism.

2021 BMC Genomics 16 citations
Article Tier 2

Effects of nanoplastics on energy metabolism in the oriental river prawn (Macrobrachium nipponense)

Oriental river prawns exposed to polystyrene nanoplastics (5–40 mg/L) for up to 28 days showed concentration- and time-dependent decreases in survival and energy metabolism, including disrupted glycogen and triglyceride content, reduced metabolic enzyme activity, and altered gene expression of energy pathways.

2020 Environmental Pollution 110 citations
Article Tier 2

Role of Mn-LIPA in Sex Hormone Regulation and Gonadal Development in the Oriental River Prawn, Macrobrachium nipponense

Researchers cloned and characterized the lysosomal acid lipase gene Mn-LIPA from the oriental river prawn Macrobrachium nipponense and examined its role in sex hormone regulation and gonadal development. The study found that Mn-LIPA expression patterns correlate with reproductive maturation and sex-specific hormone profiles in this commercially farmed freshwater shrimp.

2024 International Journal of Molecular Sciences 7 citations
Article Tier 2

Toxicokinetics of microplastics in Macrobrachium nipponense and their impact on the bioavailability of loaded pollutants

Researchers studied the toxicokinetics of microplastics in the freshwater prawn Macrobrachium nipponense, tracking uptake, distribution, and clearance across tissues and examining impacts on antioxidant defenses and immune function.

2024 Journal of Hazardous Materials 5 citations
Article Tier 2

Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense

Researchers found that polystyrene nanoplastics significantly decreased molting frequency and induced oxidative stress in adult freshwater prawns, with effects on antioxidant enzyme activities observed at environmentally relevant concentrations.

2022 Fish & Shellfish Immunology 37 citations
Article Tier 2

Molecular responses to pollution stress in glass eels (Anguilla anguilla): Gene expression changes associated with varying contamination levels and temperature across estuaries

Researchers measured gene expression in European eel glass eels entering estuaries with varying levels of microplastic and heavy metal contamination, finding that pollution and temperature shifts alter stress-response and metabolic gene expression in ways that may impair survival.

2025 Aquatic Toxicology
Article Tier 2

Molecular characterization and transcriptional response to TiO2–GO nanomaterial exposure of two molt-related genes in the juvenile prawn, Macrobrachium rosenbergii

Researchers studied how exposure to titanium dioxide-graphene oxide nanoparticles — materials used in industrial water treatment — disrupts the expression of two genes that control molting in freshwater prawns. Suppressing these molt-regulating genes could impair growth in crustaceans, raising concerns about the ecological impact of engineered nanomaterials entering aquatic environments.

2023 Scientific Reports 1 citations
Article Tier 2

Acute and chronic effects of polystyrene microplastics on brine shrimp: First evidence highlighting the molecular mechanism through transcriptome analysis

Researchers investigated both acute and chronic toxicity of polystyrene microplastics on brine shrimp, using transcriptome analysis to uncover molecular mechanisms. While acute exposure did not significantly affect survival, chronic exposure led to concentration-dependent bioaccumulation and increased reactive oxygen species generation, with gene expression analysis revealing disrupted metabolic and stress response pathways.

2020 Journal of Hazardous Materials 176 citations
Article Tier 2

Noncoding Variation and Transcriptional Plasticity Promote Thermal Adaptation in Oysters by Altering Energy Metabolism

Comparative genomic and transcriptomic analysis of two closely related oyster species from warm and cold environments found that noncoding sequence divergence and adaptive transcriptional plasticity underpin thermal adaptation, with warm-adapted oysters showing higher plasticity in energy metabolism genes that up-regulate ATP production and lipid catabolism in response to heat.

2021 Molecular Biology and Evolution 68 citations
Article Tier 2

Transcriptional response in the whiteleg shrimp (Penaeus vannamei) to short-term microplastic exposure

Researchers exposed whiteleg shrimp (Penaeus vannamei) to microplastics for 96 hours and used transcriptomics to profile gene expression changes, finding significant upregulation of stress response, immune, and detoxification pathways, indicating that even short-term microplastic exposure triggers a broad molecular stress response.

2021 Aquaculture Reports 26 citations
Article Tier 2

Seasonal tissue-specific gene expression reveals reproductive and stress-related transcriptional systems in wild crown-of-thorns starfish

This paper is not about microplastics; it maps seasonal gene expression changes in the crown-of-thorns starfish, finding that summer reproductive activity is governed by hundreds of hormonal and stress-response genes.

2023
Article Tier 2

Effects of Microplastics, Polystyrene, and Polyethylene on Antioxidants, Metabolic Enzymes, HSP-70, and Myostatin Expressions in the Giant River Prawn Macrobrachium rosenbergii: Impact on Survival and Growth

Researchers exposed juvenile giant river prawns (Macrobrachium rosenbergii) to polystyrene microspheres and polyethylene microparticles and found that both types reduced survival and growth while increasing oxidative stress markers and altering expression of heat shock proteins and myostatin, with polystyrene causing more severe effects.

2021 Archives of Environmental Contamination and Toxicology 34 citations