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61,005 resultsShowing papers similar to Uncovering the nexus of human health hazards of nanoplastics, gut-dysbiosis and antibiotic-resistance
ClearThe ant that may well destroy a whole dam: a systematic review of the health implication of nanoplastics/microplastics through gut microbiota
This systematic review summarizes existing research on how nanoplastics and microplastics disrupt gut bacteria in various organisms. The findings show that plastic particle exposure consistently alters gut microbiome composition, which in turn affects the host's immune function, metabolism, and overall health. These gut bacteria changes may be a key pathway through which microplastics harm human health.
How microplastics and nanoplastics shape antibiotic resistance?
This review examines how micro- and nanoplastics act as vectors for antibiotic resistance genes, facilitating their spread through environmental and biological systems by creating selective pressure and hosting microbial communities that exchange resistance determinants.
Microplastics Versus Microbiome: The Infantile Gut’s Battle for Health
This review examines how microplastics and nanoplastics disrupt the developing gut microbiome in infants, covering potential effects on microbial stabilization, antibiotic resistance gene transfer through biofilm formation, and implications for long-term metabolic and immune health.
Unraveling the effect of micro/nanoplastics on the occurrence and horizontal transfer of environmental antibiotic resistance genes: Advances, mechanisms and future prospects
This review examines how micro- and nanoplastics promote the spread of antibiotic resistance genes in the environment. The tiny plastic particles create conditions that help bacteria exchange resistance genes more easily by generating oxidative stress, making cell membranes more permeable, and providing surfaces where resistant bacteria can form communities. This is a growing public health concern because antibiotic-resistant infections are increasingly difficult to treat.
The role of gut microbiota in MP/NP-induced toxicity
This review summarizes how micro- and nanoplastics disrupt gut bacteria and why that matters for overall health. The tiny plastic particles change the composition and function of the gut microbiome, which can trigger inflammation, weaken the intestinal barrier, and potentially contribute to diseases beyond the gut through the immune and nervous systems.
What is the micro- and nanoplastics impact on pathogenic microorganisms?
This perspective piece reviewed emerging evidence on how micro- and nanoplastics interact with pathogenic microorganisms, potentially enhancing pathogen survival, antibiotic resistance gene transfer, and virulence. The authors highlight the plastisphere as a habitat that may selectively enrich and amplify microbial pathogens.
Do Engineered Nanomaterials Affect Immune Responses by Interacting With Gut Microbiota?
This review examined evidence that engineered nanomaterials including nanoplastics can indirectly modulate immune responses by altering gut microbiota composition, finding that while direct immunotoxicity is often mild, microbiome disruption provides an indirect pathway through which nanomaterials may impair host immunity.
Micro(nano)plastics and their potential impact on human gut health: a narrative review
This narrative review synthesizes evidence on how microplastics and nanoplastics affect the human gut, discussing ingestion routes, gut barrier interactions, microbiome disruption, and potential systemic health effects.
Exploring Bacterial Interactions with Microplastics in the Human Gut Microbiome
This review explored how microplastics interact with bacteria in the human gut microbiome, examining evidence that plastic particles can alter microbial community composition, enable colonization by pathogens, and facilitate horizontal gene transfer of antibiotic resistance genes. The gut microbiome appears to be a significant site of microplastic-microorganism interaction.
Microplastics as vectors for antibiotic resistance genes and their implications for gut health
This review explains how microplastics in the environment serve as platforms for antibiotic-resistant bacteria to grow, creating what scientists call a 'plastisphere.' When people ingest these contaminated microplastics through food and water, the antibiotic-resistant genes may transfer to gut bacteria, potentially making infections harder to treat with standard antibiotics.
Gut microbiota, a key to understanding the knowledge gaps on micro-nanoplastics-related biological effects and biodegradation
This review explores how micro- and nanoplastics affect the community of microorganisms living in the gut, and how those same gut microbes might be able to break down plastic particles. Swallowed microplastics can disrupt the balance of gut bacteria, potentially leading to various diseases. On the other hand, some gut bacteria can actually degrade plastics into smaller, less harmful molecules, opening a possible avenue for biological cleanup.
Interactions between microplastics and microbiota in a One Health perspective
This review examines how microplastics interact with microbial communities across human, animal, and environmental settings using a One Health framework. Microplastics disrupt the normal balance of microbiota in the gut, soil, and water, and serve as surfaces where harmful bacteria and antibiotic resistance genes accumulate and spread. The authors argue that understanding these microplastic-microbe interactions across all domains of life is essential for protecting both ecosystem and human health.
Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects
This expert review examined the biological and epigenetic effects of micro- and nanoplastics on living organisms. The study suggests that while intestinal uptake of plastic particles appears relatively low and size-dependent, nanoplastics may dysregulate molecular signaling pathways, alter gut microbiota composition, and induce transgenerational epigenetic changes potentially linked to metabolic disorders.
A review on the effect of micro- and nano-plastics pollution on the emergence of antimicrobial resistance
This review highlights how microplastics serve as breeding grounds for antimicrobial resistance genes, examining the overlooked interaction between plastic pollution and antibiotic resistance that poses combined threats to environmental and human health.
Understanding the Interplay between Antimicrobial Resistance, Microplastics and Xenobiotic Contaminants: A Leap towards One Health?
This review examines the interplay between antimicrobial resistance, microplastics, and xenobiotic contaminants in the environment, highlighting how microplastics can serve as vectors for antibiotic-resistant bacteria and genes, posing combined threats to ecosystem and human health.
Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health
This review explores how microplastics interact with microorganisms in the environment and within the gut, examining implications for both animal and human health. Researchers found that microplastics can alter gut microbiota composition, promote the spread of antibiotic-resistant bacteria, and amplify the toxicity of other environmental pollutants. The study suggests that the interaction between microplastics and gut microorganisms is an important emerging area for understanding health risks.
A critical review of microbiological colonisation of nano- and microplastics (NMP) and their significance to the food chain
This review examined how nano- and microplastics become colonized by diverse microbial communities in aquatic and terrestrial environments, highlighting how these 'plastisphere' biofilms may harbor pathogens and facilitate the spread of antibiotic resistance genes through the food chain.
Are Microplastics Toxic? A Review from Eco-Toxicity to Effects on the Gut Microbiota
This review summarizes existing research on the toxicity of micro- and nanoplastics, from environmental organisms to effects on gut bacteria. Studies show these particles can cause oxidative stress, disrupt energy metabolism, and damage genes in a range of species. With micro- and nanoplastics now found in human blood, lung tissue, and placentas, the authors stress that much more research is needed to understand the full health risks to people.
How micro-/nano-plastics influence the horizontal transfer of antibiotic resistance genes - A review
This review examines how micro- and nanoplastics help spread antibiotic resistance genes between bacteria -- a major global health threat. The tiny plastic particles can act as platforms where bacteria exchange DNA carrying drug-resistance instructions, potentially making infections harder to treat. The effect depends on the type, size, and concentration of plastics, and has been documented in sewage, livestock farms, and landfills.
Determining the Contribution of Micro/Nanoplastics to Antimicrobial Resistance: Challenges and Perspectives
This review examines how microplastics in the environment serve as surfaces where antibiotic-resistant bacteria can grow and exchange resistance genes, potentially worsening the global antimicrobial resistance crisis. Researchers found that the unique surface properties of micro- and nanoplastics create favorable conditions for the spread of antibiotic resistance genes among microorganisms. The study highlights that microplastic pollution and antibiotic resistance are interconnected environmental health challenges that may need to be addressed together.
Micro- and Nanoplastics as Emerging Threats to Both Terrestrial and Aquatic Animals: A Comprehensive Review
This comprehensive review examined how micro- and nanoplastics enter livestock and terrestrial animals through ingestion, inhalation, and dermal contact, accumulating in organs and disrupting physiological functions. A key finding highlighted is that MNPs facilitate horizontal transfer of antimicrobial resistance genes, exacerbating the global AMR challenge in agricultural settings.
Micro- and nanoplastics facilitate the propagation of antimicrobial resistance in mixed microbial consortia
Researchers examined how micro- and nanoplastics affect the spread of antimicrobial resistance in mixed microbial communities. The study found that nanoplastics were particularly potent at amplifying resistance gene mobility and horizontal gene transfer by elevating reactive oxygen species, damaging cell membranes, and activating stress responses that upregulate conjugation and DNA exchange mechanisms.
Micro- and Nanoplastics as Emerging Environmental Materials: GreenChemistry Insights into Gut Microbiota Disruption and Chronic DiseasePathways
Researchers reviewed how micro- and nanoplastics accumulate in the gastrointestinal tract and disrupt gut microbiota composition, finding evidence linking these exposures to reduced microbial diversity, gut barrier dysfunction, systemic inflammation, and potential contributions to chronic diseases including metabolic disorders and neurodegeneration.
[Effect of microand nanoplastics on the gastrointestinal mucosa and intestinal microbiome].
This review examines how micro- and nanoplastics entering through the food chain affect the gastrointestinal tract, finding evidence of disruption to gut mucosal integrity and intestinal microbiome composition, with implications for digestive health and systemic immune function.