We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Microplastics: A threat for developing and repairing organs?
ClearReview: Microplastics: A threat for developing and repairing organs? — R1/PR8
This review synthesizes evidence on how micro- and nanoplastics (MNPs) affect organ development and repair processes in humans and laboratory rodents, noting that MNPs have been detected in virtually every human tissue including the placenta. Early developmental windows are particularly vulnerable because MNPs and their chemical additives can disrupt genome programming and hormonal signaling during critical growth phases. The review concludes that MNPs and their leached chemicals can impair both normal development and the healing processes that reuse developmental pathways after injury.
Review: Microplastics: A threat for developing and repairing organs? — R1/PR7
This review examines how micro- and nanoplastics (MNPs) can interfere with organ development and repair across the human lifespan. MNPs have been detected throughout the body, including the placenta, raising concerns that early-life exposure could disrupt fetal programming and increase disease risk. The authors also assess how chemical additives that leach from plastic particles may compound the harm, concluding that MNPs have measurable effects on developing and regenerating organs.
Review: Microplastics: A threat for developing and repairing organs? — R0/PR3
This peer review document covers a study compiling evidence that micro- and nanoplastics (MNP) and their chemical additives can impair developmental and regenerative processes across multiple organs, including the placenta, liver, lung, and nervous system, based on human and rodent data. The review raises particular alarm about exposure during early developmental windows when genomic programming is occurring. These findings suggest that the ubiquitous presence of MNP in the human body may carry underappreciated risks for fetal health and tissue repair throughout life.
Review: Microplastics: A threat for developing and repairing organs? — R0/PR2
This comprehensive review synthesizes evidence showing that micro- and nanoplastics have been detected in virtually every human organ, including the placenta, raising serious concerns about their effects during fetal development and organ repair in adults. The authors find that microplastic particles and their associated chemical additives can disrupt hormones, trigger inflammation, and interfere with genetic programming during critical developmental windows. The review concludes that human exposure to microplastics likely increases the risk of developmental disorders and impairs the body's ability to heal damaged tissue, making this an urgent medical research priority.
Author comment: Microplastics: A threat for developing and repairing organs? — R0/PR1
This review examines how micro- and nanoplastics and their chemical additives may disrupt human developmental and regenerative processes, finding evidence across multiple organ systems in both humans and animal models that plastic particle exposure during critical growth windows can impair organ development and repair.
Recommendation: Microplastics: A threat for developing and repairing organs? — R0/PR4
This peer review recommendation evaluates a paper documenting that micro- and nanoplastics (MNP) have been detected throughout the human body, including in the placenta, and summarizes evidence that MNP and their chemical additives can disrupt developmental and organ-repair processes in humans and rodent models. Early life stages and organ regeneration appear particularly vulnerable because developmental pathways are especially sensitive to environmental disruptors. The findings underscore concern that widespread MNP exposure could impair fetal development and healing across multiple organ systems.
Decision: Microplastics: A threat for developing and repairing organs? — R1/PR10
This review examines how micro- and nanoplastics (MNP) may disrupt organ development and repair processes across the human lifespan. MNP have been detected throughout the human body — including the placenta — and their chemical additives can interfere with critical developmental windows, potentially raising long-term disease risk. The review also finds that MNP may impair the body's ability to repair organs after injury, representing a threat that extends well beyond initial exposure.
Recommendation: Microplastics: A threat for developing and repairing organs? — R1/PR9
This peer review document is a referee recommendation for the paper 'Microplastics: A threat for developing and repairing organs?' (the underlying study reviews evidence that micro- and nanoplastics disrupt organ development and repair across the human lifespan, including detection in the placenta). As a review decision document rather than a primary study, it reflects the academic evaluation process for a significant microplastics-and-human-health paper.
Author comment: Microplastics: A threat for developing and repairing organs? — R1/PR6
This is an author response document in the peer review of the paper "Microplastics: A threat for developing and repairing organs?" — it repeats the same abstract as the review itself. The underlying review synthesizes evidence that micro- and nanoplastics detected throughout the human body, including the placenta, can impair organ development in fetuses and repair processes in adults, with effects compounded by chemical additives leaching from the plastic particles.
Micro- and nanoplastics: Emerging environmental threats to the Developmental Origins of Health and Disease
This review examines how micro- and nanoplastic exposure may contribute to chronic health conditions through the lens of developmental origins of health and disease. Evidence suggests that microplastics accumulate in human metabolic and reproductive tissues and may induce physiological and epigenetic changes that could potentially be inherited by future generations, though research into these mechanisms is still in early stages.
Impact of prenatal micro/nanoplastics exposure on intrauterine development and growth: a systematic review
This systematic review examines how exposure to micro- and nanoplastics during pregnancy may affect fetal development and growth. The research gathered evidence showing that tiny plastic particles can reach the placenta and potentially disrupt normal intrauterine development. While more research is needed, these findings raise important questions about protecting pregnant women from microplastic exposure through food, water, and air.
Microplastics: A threat to Fetoplacental unit and Reproductive systems
This review examines how micro- and nanoplastics may harm the placenta and reproductive system, particularly during pregnancy. The authors highlight that these tiny plastic particles have been found in placental tissue and may interfere with fetal development, though they note that much more research is needed to understand the full risks to mothers and babies.
Placental Exposure to Nanoplastics Threatening the Maternal and Fetal Health
This review examines how nanoplastics reaching the placenta threaten maternal and fetal health, summarizing evidence from animal and in vitro studies showing that placental nanoplastic accumulation disrupts nutrient transport, immune function, and fetal development.
Assessing microplastics as a novel threat to maternal-fetal health: Placental barrier penetration and fetal developmental consequences
This review addressed how microplastics cross the placental barrier and affect fetal development, covering cellular responses in placental tissue, animal model findings, and limited human study data. The authors concluded that transplacental microplastic transfer is a plausible mechanism for intergenerational health effects.
Decision: Microplastics: A threat for developing and repairing organs? — R0/PR5
This is a peer review decision record for a paper examining how micro- and nanoplastics (MNPs) affect organ development and repair across different life stages. The underlying research concludes that MNPs and their chemical additives can disrupt developing and regenerating organs in both humans and animal models, with early developmental windows being particularly vulnerable. The existence of this review process reflects the scientific community's rigorous scrutiny of claims about microplastic health effects, an important step toward establishing evidence-based medical consensus.
Impact of microplastics and nanoplastics on human health: Mechanistic insights and exposure pathways
This review examines how microplastics and nanoplastics enter the human body through ingestion, inhalation, and skin contact, and deposit in tissues including the lungs, kidneys, and gastrointestinal tract. Evidence indicates these particles can cross embryonic layers and reach the placenta, and may cause inflammation, oxidative stress, metabolic disruptions, and immune system effects upon interaction with biological tissues.
Impact of micro-nano plastics in daily life on human health: toxicological evaluation from the perspective of normal tissue cells and organoids
This review found that micro- and nanoplastics are present in nearly all everyday products, including food, drinks, and household items, and can enter the human body through the digestive tract, respiratory system, and body fluids. Lab studies on human cells and organoids show these tiny particles cause measurable cell damage and genetic changes, even at concentrations similar to normal environmental exposure. The findings highlight the need for long-term health monitoring, especially since these particles can transfer from a mother's placenta to her unborn child.
The Impact of Maternal Nanoplastic and Microplastic Particle Exposure on Mammal’s Offspring
This review summarizes research on how a mother's exposure to nanoplastics and microplastics during pregnancy can affect her developing baby. Studies show that these tiny plastic particles can cross the placenta and reach the fetus, potentially harming brain development, the reproductive system, metabolism, and the immune system of offspring. The review calls for more research using realistic exposure levels to better understand the risks of prenatal microplastic exposure to human babies.
Health Implications of Microplastic Exposure in Pregnancy and Early Childhood: A Systematic Review
This systematic review summarizes existing research on how microplastic exposure during pregnancy and early childhood may affect health. The evidence shows that microplastics can reach the placenta and may cause oxidative stress and inflammation, raising concerns about potential effects on fetal development and infant health during these vulnerable life stages.
Micro and nano-plastics, a threat to human health?
This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.
Nanoplastics at the Placenta–Fetal Interface: Emerging Chemical Toxicology Concerns
Researchers reviewed how nanoplastics interact with trophoblasts at the placenta-fetal interface, identifying plastic additives, surface chemistry, and adsorbed protein coronas as drivers of oxidative stress and disrupted cellular function, and calling for advanced placental models to guide developmental toxicity risk assessment.
Microplastics in humans: Current evidence of presence and their role in organ toxicity
This comprehensive review examined how microplastics enter the human body through ingestion, inhalation, dermal absorption, and maternal-fetal transfer, summarizing documented evidence of MP presence and toxic effects across multiple organs.
Microplastics in the Perinatal Period: Emerging Evidence on Maternal Exposure, Placental Transfer, and Fetal Health Outcomes
This review summarizes emerging evidence that microplastics can cross the placenta and reach developing babies, having been detected in maternal blood, placental tissue, amniotic fluid, cord blood, and breast milk. The tiny plastic particles may damage the placenta, disrupt hormones, alter immune responses, and potentially affect fetal growth and brain development. While more research is needed, the findings raise serious concerns about microplastic exposure during pregnancy and its implications for infant health.
Micro(nano)plastic and Related Chemicals: Emerging Contaminants in Environment, Food and Health Impacts
This review summarizes recent research on microplastic contamination found in all types of food, from seafood and produce to drinks and packaging, as well as in human blood, heart, placenta, and breast milk. Studies using mammals and human cells suggest microplastics can damage the lungs, kidneys, heart, nervous system, and DNA, though research is complicated by the many variables involved. The review highlights the growing evidence that microplastics and their chemical additives in food represent a real and widespread threat to human health.