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61,005 resultsShowing papers similar to Individual and combined cytotoxicity effects of positively charged polystyrene nanoplastics and ionic surfactants on budding yeast Saccharomyces cerevisiae
ClearThe influencing mechanisms of different characteristics of polystyrene microplastics on Saccharomyces cerevisiae : functional group, particle size and dosage
Researchers examined the effects of polystyrene microplastics on Saccharomyces cerevisiae, systematically varying functional group, particle size, and dosage to determine the mechanisms by which these physicochemical characteristics influence toxicity to this environmentally and industrially important yeast.
Polystyrene Nanoplastic Behavior and Toxicity on Crustacean Daphnia magna: Media Composition, Size, and Surface Charge Effects
Researchers examined how size and surface charge of polystyrene nanoplastics (20-100 nm) affected their behavior and toxicity to Daphnia magna in different water media, finding that smaller particles and certain media compositions significantly increased toxicity and aggregation patterns.
Surface charge-dependent toxicity of polystyrene nanoplastics in human lung epithelial BEAS-2B and HaCaT cells
Researchers exposed human lung epithelial cells (BEAS-2B) and skin keratinocytes (HaCaT) to positively charged, negatively charged, and neutral polystyrene nanoplastics and compared cytotoxicity outcomes. Surface charge was a critical determinant of toxicity: positively charged nanoplastics caused the most severe cell death and oxidative stress in both cell types, with lung cells more sensitive than skin cells.
Polystyrene nanoplastics and wastewater displayed antagonistic toxic effects due to the sorption of wastewater micropollutants
Researchers found that polystyrene nanoplastics and wastewater micropollutants had antagonistic toxic effects when combined, because the nanoplastics sorbed positively charged pollutants through electrostatic interactions, reducing their bioavailability to aquatic organisms.
Polystyrene nanoplastics affect growth and microcystin production of Microcystis aeruginosa
Researchers exposed Microcystis aeruginosa to polystyrene nanoplastics across a range of concentrations and tracked effects on growth, cell aggregation, and microcystin production and release throughout the full growth cycle. They found a dose-dependent growth inhibition and increased aggregation at high concentrations, but nanoplastics at 50 mg/L paradoxically stimulated a period of rapid growth, with complex effects on intracellular and extracellular microcystin levels.
Insights into the synergistic toxicity mechanisms caused by nano- and microplastics with triclosan using a dose-dependent functional genomics approach in Saccharomyces cerevisiae
Researchers used yeast functional genomics to investigate the combined toxicity of polystyrene nano- and microplastics with the antimicrobial compound triclosan. They found that the combined exposure produced synergistic toxic effects that were more harmful than either contaminant alone, disrupting cellular processes related to membrane integrity and protein function. The study provides molecular-level evidence that microplastics may amplify the toxicity of co-occurring chemical pollutants.
Cytotoxic effects of polystyrene nanoplastics with different surface functionalization on human HepG2 cells
Researchers exposed human liver (HepG2) cells to 50 nm polystyrene nanoparticles with three different surface chemistries and found that amino-functionalized particles caused the greatest cytotoxicity and oxidative stress, demonstrating that surface charge and chemistry — not just particle size — determine nanoplastic harm to human cells.
Effects of polystyrene nanoplastics on extracellular polymeric substance composition of activated sludge: The role of surface functional groups
Researchers investigated how three types of polystyrene nanoplastics with different surface functional groups affect activated sludge used in wastewater treatment. All three types significantly reduced total protein production in the sludge and caused cellular oxidative stress and membrane damage, with positively charged particles causing the most harm. The findings suggest that nanoplastic contamination in wastewater could impair the biological processes essential for effective sewage treatment.
Nanopolystyrene size effect and its combined acute toxicity with halogenated PAHs on Daphnia magna
Researchers tested how nanopolystyrene particle size affects toxicity to Daphnia magna water fleas alone and in combination with halogenated polycyclic aromatic hydrocarbons, finding smaller particles (30 nm) were far more toxic than larger ones (1 µm) and that the plastic-chemical mixtures showed antagonistic effects — reducing combined toxicity below what either contaminant caused alone.
Hazard evaluation of polystyrene nanoplastic with nine bioassays did not show particle-specific acute toxicity
Researchers tested polystyrene nanoplastics across nine toxicity assays using ten organisms and found no particle-specific acute toxicity — apparent toxicity in three assays was traced to water-soluble additives (surfactants and a biocide) in the commercial nanoplastic preparations rather than the plastic particles themselves.
Use of Saccharomyces cerevisiae as new technique to remove polystyrene from aqueous medium: modeling, optimization, and performance
Researchers tested whether common baker's yeast (Saccharomyces cerevisiae) could remove polystyrene microplastics from water, achieving up to 95% removal under optimized conditions. The yeast works as a natural clumping agent that binds to microplastic particles and helps them settle out of the water. This low-cost, non-toxic approach could offer a practical biological method for cleaning microplastics from contaminated water.
Influence of ionic surfactant contaminants on polystyrene-air bubble interactions for microplastics removal from wastewater
Researchers investigated how ionic surfactants present in municipal and industrial wastewater affect the efficiency of froth flotation for removing polystyrene microplastics. Surfactant type and concentration strongly influenced bubble-particle interactions, with some surfactants dramatically reducing removal efficiency, highlighting a challenge for flotation-based MP removal systems.
Cellular interactions with polystyrene nanoplastics—The role of particle size and protein corona
Researchers investigated how polystyrene nanoplastics interact with mammalian cells, finding that particle size and the protein corona that forms around particles in biological fluids strongly influence cellular uptake and toxicity. Smaller nanoplastics penetrated cell membranes more readily and caused greater disruption, suggesting that the tiniest plastic particles may pose the greatest biological risk.
Effect of salinity and humic acid on the aggregation and toxicity of polystyrene nanoplastics with different functional groups and charges
Researchers showed that surface charge governs nanoplastic behavior in water — higher salinity caused negatively charged nanoplastics to aggregate while positively charged particles remained stable — and that humic acid (dissolved organic matter) alleviated toxicity to Daphnia, increasing survival from 15% to nearly 100% in some cases.
Cytotoxicity of amine-modified polystyrene MPs and NPs on neural stem cells cultured from mouse subventricular zone
Researchers tested the effects of polystyrene microplastics and nanoplastics with a positive surface charge on neural stem cells from mouse brains. Both sizes of particles reduced cell survival, but nanoplastics were significantly more toxic at lower concentrations, causing cell death and preventing stem cells from developing into mature brain cells. These findings suggest that nanoplastics that reach the brain could potentially harm the nervous system's ability to repair and maintain itself.
The effects of two sized polystyrene nanoplastics on the growth, physiological functions, and toxin production of Alexandrium tamarense
Polystyrene nanoplastics at two size ranges were found to inhibit growth and alter physiological functions of the harmful algal bloom dinoflagellate Alexandrium tamarense, with larger particles having stronger effects on toxin production and smaller particles causing more pronounced growth inhibition.
Investigating the toxicities of different functionalized polystyrene nanoplastics on Daphnia magna
Researchers compared the toxicity of plain and surface-modified polystyrene nanoplastics on Daphnia water fleas, finding that unmodified particles were most lethal by activating stress kinase pathways, while surface-functionalized particles were less toxic — largely because positively charged particles aggregated rapidly in water and reduced their effective exposure concentration.
Uptake and toxicity of polystyrene micro/nanoplastics in gastric cells: Effects of particle size and surface functionalization
Researchers evaluated the uptake and toxicity of polystyrene micro- and nanoplastics in human gastric cells, comparing different sizes and surface treatments. The study found that smaller 50-nanometer particles were taken up at significantly higher rates, with positively charged aminated particles being the most toxic, causing cytotoxicity at lower concentrations and higher rates of cell death.
What Is on the Outside Matters—Surface Charge and Dissolve Organic Matter Association Affect the Toxicity and Physiological Mode of Action of Polystyrene Nanoplastics toC. elegans
Researchers investigated how surface charge and organic matter coatings affect the toxicity of polystyrene nanoplastics to the nematode C. elegans. Positively charged nanoplastics were over 60 times more toxic than negatively charged ones, and organic matter coatings reduced toxicity across all particle types. The findings suggest that surface chemistry plays a critical role in nanoplastic toxicity and should be considered when assessing environmental risks.
Toxic effects of polystyrene nanoplastics on MDA-MB-231 breast cancer and HFF-2 normal fibroblast cells: viability, cell death, cell cycle and antioxidant enzyme activity
Researchers exposed human breast cancer cells and normal skin cells to polystyrene nanoplastics and found that smaller particles at higher concentrations caused significant cell death through apoptosis (programmed cell death) and reduced the cells' ability to defend against oxidative damage. The dose- and size-dependent toxicity suggests that nanoplastics small enough to enter cells are more biologically harmful than larger particles.
Does triclosan adsorption on polystyrene nanoplastics modify the toxicity of single contaminants?
Researchers investigated whether triclosan adsorption onto polystyrene nanoplastics modifies the toxicity of each contaminant individually, using a multi-tiered approach to assess how nanoplastic carrier effects alter the combined hazard of this common antimicrobial agent in aquatic environments.
Combined Toxicity of Polystyrene Nanoplastics and Pyriproxyfen to Daphnia magna
Researchers evaluated the combined toxic effects of polystyrene nanoplastics and the insecticide pyriproxyfen on the water flea Daphnia magna under both acute and chronic exposure conditions. They found that nanoplastics initially reduced the acute toxicity of the pesticide within 24 hours but worsened chronic effects over longer periods. The study suggests that nanoplastics can alter how other environmental contaminants affect aquatic organisms, complicating risk assessments.
Role of nanoparticle surface charge in their toxicity
This study examined how surface charge (carboxyl vs. amino functionalization) affects the toxicity of polystyrene nanoparticles formed during plastic degradation, noting that nanoparticle toxicity can differ substantially from bulk material. Results highlighted that surface chemistry is a critical determinant of nanoparticle behavior in biological environments.
Aggregation kinetics of different surface-modified polystyrene nanoparticles in monovalent and divalent electrolytes
Researchers investigated how surface chemistry and morphology affect the clumping behavior (aggregation kinetics) of polystyrene nanoplastics in water, finding that surface charge and functional groups strongly govern stability, while dissolved organic matter can either inhibit or promote aggregation depending on concentration and whether mono- or divalent ions are present.