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Papers
20 resultsShowing papers similar to Gut Microbiome and Small RNA Integrative-Omic Perspective of Meconium and Milk-FED Infant Stool Samples
ClearInfant microbiota formation: mother – placenta – fetus – baby
This review examines how infant gut microbiota forms through the mother-placenta-fetus-baby pathway, with colonization beginning during the prenatal period. The study discusses how factors such as delivery mode, breastfeeding, and maternal health shape early microbial communities that influence long-term health outcomes.
Investigating prenatal and perinatal factors on meconium microbiota: a systematic review and cohort study
Researchers reviewed 69 studies and conducted a cohort study to understand what shapes the gut microbiome of newborns at birth, finding that conditions during delivery — such as cesarean section versus vaginal birth — have a much stronger influence on early microbiota than factors during pregnancy. This suggests the initial seeding of a baby's gut microbiome happens mainly during the birth process itself.
Maternal and early life exposures and their potential to influence development of the microbiome
This review explores how maternal and early-life environmental exposures, including to emerging contaminants, can influence the development of the infant microbiome. Researchers found that factors such as nutrition, chemical exposures, and living conditions during pregnancy and early childhood shape the microbial communities that are critical for immune and metabolic development. The study highlights the importance of understanding how environmental pollutants may disrupt healthy microbiome establishment in vulnerable populations.
Microplastics Versus Microbiome: The Infantile Gut’s Battle for Health
This review examines how microplastics and nanoplastics disrupt the developing gut microbiome in infants, covering potential effects on microbial stabilization, antibiotic resistance gene transfer through biofilm formation, and implications for long-term metabolic and immune health.
Associations of Plastic Bottle Exposure with Infant Fecal Microbiota, Short-Chain Fatty Acids, and Growth
Researchers investigated associations between plastic bottle use and infant gut health, examining whether exposure influences early fecal microbiota composition, short-chain fatty acid levels, and growth trajectories in infants.
Integration of Non-Coding RNA and mRNA Profiles Reveals the Mechanisms of Rumen Development Induced by Different Types of Diet in Calves
Researchers used integrated non-coding RNA and mRNA profiling to reveal molecular mechanisms underlying rumen development in calves fed different diet types, identifying regulatory networks that influence gastrointestinal maturation.
Socializing Models During Lactation Alter Colonic Mucosal Gene Expression and Fecal Microbiota of Growing Piglets
Researchers investigated how intermittent or continuous social contact with neighboring litters during lactation affects piglet gut health, using RNA sequencing and 16S rRNA microbiome analysis to show that enriched social environments alter colonic mucosal gene expression and fecal microbiota composition in growing piglets.
Editorial: Impact of gut ecosystem in health and diseases: microbiome, mucosal barrier and cytokine milieu
This editorial introduces a research collection examining the gut ecosystem's role in health and disease, focusing on how the perinatal and lifetime 'exposome' (diet, pre/probiotics, environmental factors) shapes microbiome composition, mucosal barrier function, and cytokine/chemokine signaling in intestinal immunity.
Fate of microplastics in human digestive in vitro environment and study of the dialogue between epithelium, microbiota and mucus
Researchers used an in vitro human digestive model to track the fate of microplastics through simulated gastrointestinal conditions, investigating how MPs interact with digestive physico-chemical parameters, the epithelium, gut microbiota, and mucus layer, with particular attention to the vulnerable infant population.
In vitro gut models reveal how microplastics interact with human microbiome in adults and infants.
Researchers used in vitro gut models to investigate how microplastics interact with the human gut microbiome in both adults and infants, finding differences in microbial community responses depending on life stage. The study provides mechanistic insights into how microplastic ingestion may differentially affect gut health across age groups.
Resilience to Global Health Challenges Through Nutritional Gut Microbiome Modulation
This review explores how gut microbiome composition during early life influences long-term health, and how nutritional strategies can help build resilience against chronic diseases. Researchers highlight that environmental factors including microplastics and other contaminants can disrupt the developing gut microbiome, potentially contributing to allergies, obesity, and neurological conditions. The study suggests that targeted nutritional interventions to support healthy gut bacteria could help counteract some of these environmental exposures.
Exploring Protein Functions of Gut Bacteriome and Mycobiome in Thai Infants Associated with Atopic Dermatitis Through Metaproteomic and Host Interaction Analysis
Researchers analyzed gut microbiome protein expression in Thai infants with atopic dermatitis using metaproteomic analysis. The study found reduced abundance of probiotic species and increased pathogenic bacteria and fungi in affected infants, along with stress-related protein expression patterns, suggesting that gut microbial imbalances and their functional interactions may play a role in this allergic skin condition.
Interactions of microplastics with the human gut microbiota of adults and infants using in vitro gut models
Using in vitro gut models mimicking adult and infant digestive systems, researchers studied how microplastics interact with the human gut microbiota, finding that plastic particles can alter microbial community composition. These disruptions to the gut microbiome could have downstream implications for immune function, digestion, and overall health, particularly in vulnerable infants.
[Effect of microand nanoplastics on the gastrointestinal mucosa and intestinal microbiome].
This review examines how micro- and nanoplastics entering through the food chain affect the gastrointestinal tract, finding evidence of disruption to gut mucosal integrity and intestinal microbiome composition, with implications for digestive health and systemic immune function.
Microplastics-gut microbiota interactions in an in vitro model of the toddler colon
Researchers used an in vitro model of the toddler colon to investigate how microplastics interact with the gut microbiota in young children. The study examined changes in microbial community composition and metabolic activity following microplastic exposure, providing early evidence of potential disruption to the developing gut ecosystem.
A probiotic for preventing microplastic toxicity: Clostridium dalinum mitigates microplastic-induced damage via microbiota-metabolism-barrier interactions
Using metagenomics and metabolomics, this study found that the probiotic bacterium Clostridium dalinum reduced microplastic-induced gut damage in mice by modulating gut microbiota composition, metabolic pathways, and intestinal barrier integrity.
Microplastics and their interactions with microbiota
This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.
Toxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review
This review examines how various environmental pollutants affect the gut microbiome — the community of microorganisms in the intestinal tract. Microplastics are among the pollutants discussed, and their ability to alter gut microbiota composition is increasingly recognized as a mechanism by which plastic particles may harm human and animal health.
Exploring the Crucial Role of the Gut Microbiome in Advancing Food Processing Technologies
This review explores the role of gut microbiome composition in food processing and technology development, examining how microbial communities influence fermentation, nutrient bioavailability, and food safety, with implications for probiotic and prebiotic product design.
Microplastic-associated gut microbial profile and antibiotic resistance in preschool children: a multicentre cross-sectional study in China
In a multicentre study of 335 preschool children across three Chinese cities, researchers detected eight types of microplastics in fecal samples at a median concentration of 212.1 micrograms per gram. The study found that microplastic exposure was associated with changes in gut microbiota composition and function, including metabolic pathways related to macronutrients and vitamins, as well as a relationship with antibiotic resistance gene abundance.