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61,005 resultsShowing papers similar to Current Levels of Environmental Exposure to Cadmium in Industrialized Countries as a Risk Factor for Kidney Damage in the General Population: A Comprehensive Review of Available Data
ClearMicroplastics and Kidneys: An Update on the Evidence for Deposition of Plastic Microparticles in Human Organs, Tissues and Fluids and Renal Toxicity Concern
This review summarizes the growing evidence that microplastics are found throughout the human body, including in the placenta, lungs, liver, heart, blood, and breast milk. While direct evidence for kidney damage in humans is still lacking, animal studies show that microplastics can cause kidney inflammation, cell death, and oxidative stress. The findings highlight that microplastics are accumulating in virtually every human organ, though the long-term health consequences remain unclear.
Effects of microplastics on the kidneys: a narrative review
This review summarizes growing evidence that microplastics can accumulate in the kidneys, where they may trigger inflammation, oxidative stress, and cellular damage that could worsen kidney function. People with chronic kidney disease may be especially vulnerable because impaired kidney filtration could allow microplastics to build up more readily in their bodies.
Microplastics Exacerbate Cadmium-Induced Kidney Injury by Enhancing Oxidative Stress, Autophagy, Apoptosis, and Fibrosis
Researchers exposed mice to microplastics and cadmium for three months and found that microplastics significantly worsened cadmium-induced kidney injury. The combined exposure enhanced oxidative stress, autophagy, cell death, and tissue scarring in the kidneys beyond what cadmium alone caused. The study suggests that microplastics may act as amplifiers of heavy metal toxicity in organ systems.
The gut microbiota: A key player in cadmium toxicity - implications for disease, interventions, and combined toxicant exposures
This review examines how cadmium, a toxic heavy metal found in contaminated soil and water, damages health partly by disrupting gut bacteria. The connection to microplastics is significant because microplastics are known to absorb and carry heavy metals like cadmium, potentially increasing our exposure to these toxins and compounding the damage to our gut health.
A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle
This review summarizes how heavy metals like lead, arsenic, and cadmium damage kidneys in cattle, building up in the body and food chain over time. Even low doses cause oxidative stress and organ damage that worsens with prolonged exposure. While focused on cattle, the findings are relevant to microplastics research because microplastics can absorb and transport these same heavy metals into animals and humans through contaminated food and water.
Unveiling the impacts of microplastics on cadmium transfer in the soil-plant-human system: A review
A meta-analysis found that microplastics significantly increase soil cadmium bioavailability by 6.9% and cadmium accumulation in plant shoots by 9.3%, through both direct surface adsorption and indirect modification of soil pH and dissolved organic carbon. This enhanced cadmium mobility through the soil-plant-human food chain amplifies health risks, as co-ingestion of microplastics and cadmium increases cadmium bioaccessibility and tissue damage.
Microplastiques : une menace silencieuse pour vos reins ?
Researchers reviewed evidence on microplastic contamination and its potential effects on kidney health, noting that microplastics have been detected in kidneys and urine in humans. In vitro and animal studies suggest potential nephrotoxicity from microplastic exposure, and patients with kidney diseases may face increased risk due to higher exposure through medical procedures and reduced urinary elimination. The study calls for further research to clarify the relationship between microplastic exposure and kidney damage.
Influence of cephalexin on cadmium adsorption onto microplastic particles in water: Human health risk evaluation
Researchers studied how the antibiotic cephalexin influences the adsorption of the toxic metal cadmium onto polyethylene microplastics in water. They found that smaller microplastic particles absorbed more cadmium, and that the combined presence of cadmium and microplastics poses health risks, particularly for children exposed through contaminated groundwater. The study provides evidence that microplastics can act as carriers for heavy metals, potentially increasing human exposure to toxic substances.
Environmental toxicants and nephrotoxicity: Implications on mechanisms and therapeutic strategies
This review examines how environmental toxicants, including microplastics, phthalates, and bisphenol A, can damage the kidneys. These substances can accumulate in kidney tissue after being swallowed, inhaled, or absorbed through the skin, triggering inflammation, oxidative stress, and cell death. The findings highlight that the kidneys, which filter about 200 liters of fluid daily, are particularly vulnerable to harm from the growing levels of plastic-related pollutants in our environment.
Sorption properties of cadmium on microplastics: The common practice experiment and A two-dimensional correlation spectroscopic study
Laboratory experiments examined how cadmium adsorbs onto microplastics of different polymer types and aging states, finding that surface chemistry and weathering significantly affect how much heavy metal the plastics can carry. This matters because microplastics contaminated with heavy metals represent a dual pollution risk when ingested by aquatic organisms.
Microplastics may increase the environmental risks of Cd via promoting Cd uptake by plants: A meta-analysis
This meta-analysis found that microplastics in soil can increase how much cadmium (a toxic heavy metal) plants absorb. This is concerning because it means microplastic pollution could make our food crops more contaminated with heavy metals, adding another health risk on top of the plastics themselves.
Microplastics and CKD: Are we overlooking the role of ecotoxins
This review argues that microplastics deserve greater consideration as a contributing factor to chronic kidney disease, synthesizing evidence that MPs can accumulate in renal tissue, trigger inflammation and oxidative stress, and may represent an underappreciated environmental driver of CKD.
Microplastics as a vehicle of heavy metals in aquatic environments: A review of adsorption factors, mechanisms, and biological effects
This review summarizes how microplastics in water can absorb and carry toxic heavy metals like lead and cadmium, making them more dangerous to aquatic life than either pollutant alone. Environmental factors such as water acidity, salinity, and organic matter influence how much metal sticks to microplastic surfaces. Since contaminated seafood is a major source of human exposure, understanding these interactions is important for assessing health risks.
The threat of microplastics to human kidney health: Mechanisms of nephrotoxicity and future research directions
This review examines the growing evidence that microplastics can reach and damage human kidneys, where they were first detected in 2023. Short-term exposure triggers oxidative stress and inflammation, while long-term exposure may lead to kidney scarring through a process called ferroptosis, a type of cell death linked to iron buildup. The authors propose that microplastics may also activate the immune system in kidneys through a gut-kidney connection, highlighting that kidney health is an important but overlooked concern in microplastic research.
[Effects of Aging on the Cd Adsorption by Microplastics and the Relevant Mechanisms].
This study examined how aging affects the ability of microplastics — including polyethylene and polystyrene — to adsorb the heavy metal cadmium. Weathered microplastics showed different adsorption behavior than virgin particles, which has implications for how microplastics transport toxic metals through aquatic environments.
Effects of microplastics and nanoplastics on the kidney and cardiovascular system
This review summarizes evidence that microplastics and nanoplastics found in human hearts, kidneys, blood, and urine can cause oxidative stress, inflammation, cell death, and metabolic disruption. Kidney dialysis patients may face especially high exposure, and clinical evidence suggests particulate plastic exposure is a risk factor for cardiovascular disease.
Prenatal exposure to microplastics and biomarkers of renal dysfunction in umbilical cord blood: Evidence from a birth cohort in China
Researchers analyzed placental tissue from 1,350 pregnant women in China for microplastic content and tested associations with renal biomarkers in umbilical cord blood, finding that prenatal microplastic exposure was linked to elevated markers of kidney dysfunction in newborns.
The combined effects of polystyrene of different sizes and cadmium in mouse kidney tissues
Researchers studied how polystyrene particles of different sizes combined with cadmium affect kidney health in mice. They found that smaller nanoplastic particles (100 nm) caused more severe kidney damage than larger ones (1 micrometer), and that exposure to both sizes together with cadmium produced the worst outcomes. The study suggests that in real-world conditions where plastics of various sizes coexist with heavy metals, the combined toxic effects on kidneys may be more complicated and harmful than exposure to any single contaminant.
Research on the Mechanisms of Plant Enrichment and Detoxification of Cadmium
This review examines how plants absorb, transport, and accumulate the heavy metal cadmium from contaminated soil, as well as the detoxification mechanisms plants use to cope with cadmium stress. While focused on cadmium rather than microplastics, the research is relevant because microplastics in soil can alter cadmium mobility and uptake by crops, potentially affecting food safety.
The detrimental effects of microplastic exposure on kidney function
This review explores the two-way relationship between kidney function and microplastic exposure, asking whether MPs can be cleared renally and whether kidney disease impairs their clearance. Evidence suggests MPs accumulate in kidney tissue and may contribute to disease progression, though clinical data remain limited.
Effects of Orally Ingested Microplastics on the Structure and Function of the Kidneys
This study reviewed the structural and functional effects of orally ingested microplastics on kidney tissue, synthesizing experimental evidence from animal and in vitro studies. Microplastic exposure was consistently associated with kidney histopathology including inflammation and fibrosis, with particle size, shape, and polymer type influencing the severity of renal damage.
Effects of Microplastics and Nanoplastics on the Kidneys
This review of existing research finds that tiny plastic particles from everyday items can reach your kidneys through your bloodstream and cause damage. The plastic pieces trigger inflammation and create harmful chemical reactions that can harm kidney function and may worsen chronic kidney disease. This matters because we're all exposed to these microscopic plastics daily through food, water, and air, but we're still learning how much damage they might cause to our health.
Microplastic exposure and its consequences for renal and urinary health: systematic review of in vivo studies
This systematic review examines animal studies on how microplastic exposure affects the kidneys and urinary system. The evidence suggests that microplastics can accumulate in kidney tissue and may cause inflammation and oxidative stress, raising concerns about potential long-term effects on human kidney health as our exposure to these particles continues to grow.
Influences of coexisting aged polystyrene microplastics on the ecological and health risks of cadmium in soils: A leachability and oral bioaccessibility based study
This study tested whether the presence of aged microplastics in soil changes how easily the toxic heavy metal cadmium can enter the human body through accidental soil ingestion. The results showed that aged polystyrene microplastics actually reduced cadmium absorption in the stomach phase, though the effect varied by soil type. This suggests that the interaction between microplastics and other pollutants in soil creates a complicated picture for assessing human health risks.