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20 resultsShowing papers similar to Inhibitory Effects of Jiuzao Polysaccharides on Alcoholic Fatty Liver Formation in Zebrafish Larvae and Their Regulatory Impact on Intestinal Microbiota
ClearFermented Wheat Bran Polysaccharides Improved Intestinal Health of Zebrafish in Terms of Intestinal Motility and Barrier Function
Researchers found that fermented wheat bran polysaccharides improved intestinal health in zebrafish by enhancing intestinal motility and barrier function, suggesting their potential as functional food additives for gut health.
Black Lycium barbarum polysaccharide attenuates LPS-induced intestine damage via regulation gut microbiota
Researchers studied whether a polysaccharide from black Lycium barbarum could protect against intestinal damage caused by bacterial toxins in mice. They found that the supplement alleviated intestinal tissue damage and improved gut microbiota diversity by promoting beneficial bacteria. The study suggests that this plant-derived polysaccharide may help maintain intestinal health by modulating the gut microbial community.
The Impact of Microalgae and Their Bioactive Compounds on Liver Well-being in Rats Subjected to Synthetic Phenolic Antioxidants
This review examines how microalgae and their bioactive compounds — including polysaccharides, pigments, and polyphenols — protect liver health in animal models, summarizing evidence for anti-inflammatory and antioxidant mechanisms. The authors note that algal-derived compounds show hepatoprotective effects in rodent studies, though human clinical evidence remains limited.
Korean red ginseng extract inhibits microplastic translocation via the gut−liver axis by ameliorating alcohol-induced intestinal disruption
Using a mouse model of alcohol-induced intestinal disruption, researchers found that Korean red ginseng extract reduced translocation of polystyrene microplastics from the gut to the liver by ameliorating alcohol-induced intestinal barrier damage, suggesting a potential protective role for this herbal extract.
Hepatoprotective Effect of Allium ochotense Extracts on Chronic Alcohol-Induced Fatty Liver and Hepatic Inflammation in C57BL/6 Mice
Researchers tested extracts from the plant Allium ochotense for their ability to protect against alcohol-induced liver damage in mice. The study found that the extracts improved lipid metabolism, reduced liver inflammation, and boosted antioxidant defenses, suggesting potential as a natural approach to supporting liver health in the context of chronic alcohol consumption.
Jianwei Xiaoshi oral liquid attenuates high-calorie diet-induced dyspepsia in immature rats via regulating the pancreatic secretion pathway and maintaining the homeostasis of intestinal microbiota
Researchers found that a traditional Chinese herbal medicine formula called Jianwei Xiaoshi oral liquid improved functional digestive problems in young rats fed a high-calorie diet by regulating eight key proteins involved in pancreatic digestion and restoring healthy gut bacteria balance. The findings suggest potential therapeutic benefits of this herbal remedy for diet-induced digestive disorders in children.
Effects of Yu-Ping-Feng polysaccharides (YPP) on the growth performance, intestinal health and lipid metabolism of largemouth bass (Micropterus salmoides)
This paper is not about microplastics; it investigates the effects of Yu-Ping-Feng polysaccharides on growth, intestinal health, and lipid metabolism in largemouth bass, with no connection to plastic or microplastic research.
Preparation of Polysaccharides from Qifuyin and Investigation of Their Anti-Oxidant and Regenerative Effects Based on Planaria
Researchers extracted polysaccharides from the traditional Chinese medicine formula Qifuyin using hydrothermal methods, achieving 29.9% yield and 70.1% purity, and investigated their antioxidant and regenerative effects using planaria as a model organism.
The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota -liver-brain axis
Researchers tested whether the probiotic supplement SLAB51 could counteract the harmful effects of bisphenol A (BPA), a plastic-derived chemical, in zebrafish and found it significantly restored healthy gut bacteria, reduced liver damage, and protected the brain — suggesting probiotics may help offset harm from plastic-associated chemical exposure.
Chestnut Shell Tannins: Effects on Intestinal Inflammation and Dysbiosis in Zebrafish
Researchers tested chestnut shell tannin extract in zebrafish with induced intestinal inflammation and dysbiosis, finding that tannin treatment reduced inflammatory markers and partially restored gut microbiome composition, suggesting potential as a natural anti-inflammatory dietary supplement.
Perspective on the Therapeutic Applications of Algal Polysaccharides
Researchers reviewed the extraction, structural properties, and therapeutic bioactivities of algal polysaccharides — complex carbohydrates from marine and freshwater algae — summarizing evidence for their anticancer, antiviral, antidiabetic, and immunomodulatory effects and identifying knowledge gaps needed to develop them as pharmaceuticals.
Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics in mice
Researchers found that the probiotic Lactobacillus rhamnosus GG helped protect mice from liver damage caused by polystyrene microplastic exposure. The probiotic worked by restoring healthy gut bacteria and normalizing liver metabolic pathways disrupted by the microplastics. The study suggests that supporting gut health through beneficial bacteria may help mitigate some of the toxic effects microplastics have on the liver.
Selenium-containing polysaccharide from Spirulina platensis alleviates Cd-induced toxicity in mice by inhibiting liver inflammation mediated by gut microbiota
Researchers found that selenium-containing polysaccharide from Spirulina platensis alleviates cadmium-induced liver toxicity in mice by modulating gut microbiota composition and suppressing inflammatory pathways, suggesting a protective role against heavy metal exposure.
In Vitro and In Vivo Effects of Ulvan Polysaccharides from Ulva rigida
Researchers investigated the biological activity of ulvan polysaccharides extracted from the seaweed Ulva rigida, testing them against cancer cell lines and zebrafish embryos. The study found that ulvan showed cytotoxic effects on human colon cancer cells in vitro, but the in vivo zebrafish assays revealed potential toxicity at higher concentrations, suggesting further safety evaluation is needed before therapeutic applications.
Ameliorative effects of mulberry fruit anthocyanin extract on gut microbiota and liver metabolites in high-fat and high-cholesterol diet-fed ApoE−/− mice
Researchers investigated mulberry anthocyanin extract in high-fat, high-cholesterol diet-fed mice and found it reduced LDL cholesterol and inflammatory markers while favorably shifting gut microbial composition and modulating liver metabolites including glutamine and ATP, suggesting a mechanism linking gut microbiota to atherosclerosis risk reduction.
Agrocybe cylindracea Polysaccharides Ameliorate DSS-Induced Colitis by Restoring Intestinal Barrier Function and Reprogramming Immune Homeostasis via the Gut–Liver Axis
Researchers investigated whether polysaccharides from the edible mushroom Agrocybe cylindracea could alleviate colitis in a mouse model. They found that oral administration of the polysaccharides significantly reduced disease symptoms, restored intestinal barrier integrity, and reshaped gut microbiota composition by promoting beneficial bacteria. The study positions these mushroom polysaccharides as a potential natural therapeutic that works through multiple pathways including immune modulation and gut-liver axis signaling.
Seaweed polysaccharide relieves hexavalent chromium-induced gut microbial homeostasis
Researchers found that seaweed polysaccharides can restore gut microbial balance disrupted by hexavalent chromium exposure in mice, reducing pathogenic bacteria and increasing beneficial species, suggesting a potential dietary intervention for heavy metal-induced intestinal damage.
The Interaction between Oxidative Stress Biomarkers and Gut Microbiota in the Antioxidant Effects of Extracts from Sonchus brachyotus DC. in Oxazolone-Induced Intestinal Oxidative Stress in Adult Zebrafish
Researchers found that extracts from Sonchus brachyotus DC. alleviated oxazolone-induced intestinal oxidative stress in zebrafish by modulating antioxidant enzyme activity and reshaping gut microbiota composition.
Electroacupuncture treatment ameliorates metabolic disorders in obese ZDF rats by regulating liver energy metabolism and gut microbiota
Researchers found that electroacupuncture treatment improved blood sugar and fat metabolism in obese rats by reshaping their gut bacteria and altering liver metabolic pathways. The treatment boosted beneficial gut bacteria, reduced harmful ones, and influenced key processes like fat production and amino acid metabolism in the liver. The study suggests a strong connection between the gut microbiome and liver function in metabolic health.
Protective Effect of Paeoniae Radix Alba Carbonisata on Hepatic Amyloidosis by Regulating Calcium Homeostasis
Scientists tested a traditional Chinese herbal medicine called PRAC on a serious liver condition where harmful proteins build up and damage the organ. The herb extract helped protect liver cells and reduced inflammation by fixing problems with calcium balance inside cells. While this is early research done in lab dishes and mice, it suggests this traditional remedy might help treat certain types of liver disease, though human studies are still needed.