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Perspective on the Therapeutic Applications of Algal Polysaccharides

Journal of Polymers and the Environment 2021 64 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 55 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Rachana Singh, Sonal Nigam, Surbhi Sinha Rachana Singh, Surbhi Sinha Surbhi Sinha Surbhi Sinha Sheetal K. Bhardwaj, Rachana Singh, Rokkayya Sami, Rokkayya Sami, Rachana Singh, Maria P. Nikolova, Murthy Chavali, Murthy Chavali, Surbhi Sinha

Summary

Researchers reviewed the extraction, structural properties, and therapeutic bioactivities of algal polysaccharides — complex carbohydrates from marine and freshwater algae — summarizing evidence for their anticancer, antiviral, antidiabetic, and immunomodulatory effects and identifying knowledge gaps needed to develop them as pharmaceuticals.

ABSTRACT: Algae are an enormous source of polysaccharides and have gained much interest in human flourishing as organic drugs. Algal polysaccharides have aroused interest in the health sector owing to the various bioactivities namely anticancer, antiviral, immunoregulation, antidiabetic and antioxidant effects. The research community has comprehensively described the importance of algal polysaccharides regarding their extraction, purification, and potential use in various sectors. However, regardless of all the intriguing properties and potency in the health sector, these algal polysaccharides deserve detailed investigation. Hence, the present review emphasizes extensively on the previous and latest developments in the extraction, purification, structural properties and therapeutic bioactivities of algal polysaccharides to upgrade the knowledge for further advancement in this area of research. Moreover, the review also addresses the challenges, prospective research gaps and future perspective. We believe this review can provide a boost to upgrade the traditional methods of algal polysaccharide production for the development of efficacious drugs that will promote human welfare.

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