We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to An Ilex latifolia‐containing compound tea regulates glucose–lipid metabolism and modulates gut microbiota in high‐fat diet‐fed mice
ClearAmeliorative effects of mulberry fruit anthocyanin extract on gut microbiota and liver metabolites in high-fat and high-cholesterol diet-fed ApoE−/− mice
Researchers investigated mulberry anthocyanin extract in high-fat, high-cholesterol diet-fed mice and found it reduced LDL cholesterol and inflammatory markers while favorably shifting gut microbial composition and modulating liver metabolites including glutamine and ATP, suggesting a mechanism linking gut microbiota to atherosclerosis risk reduction.
Characterizing the Gut Microbial Metabolic Profile of Mice with the Administration of Berry-Derived Cyanidin-3-Glucoside
This paper is not about microplastics — it characterizes how the berry-derived compound cyanidin-3-glucoside alters gut microbiome composition and metabolic profiles in mice.
Gut microbiota remodeling drived by dietary millet protein prevents the metabolic syndrome
Researchers found that millet bran protein extract prevented metabolic syndrome in high-fat diet mice by remodeling gut microbiota and reducing obesity, chronic inflammation, and insulin resistance. The protective effects were linked to specific gut microbial metabolites influenced by dietary millet protein.
Electroacupuncture treatment ameliorates metabolic disorders in obese ZDF rats by regulating liver energy metabolism and gut microbiota
Researchers found that electroacupuncture treatment improved blood sugar and fat metabolism in obese rats by reshaping their gut bacteria and altering liver metabolic pathways. The treatment boosted beneficial gut bacteria, reduced harmful ones, and influenced key processes like fat production and amino acid metabolism in the liver. The study suggests a strong connection between the gut microbiome and liver function in metabolic health.
Jianwei Xiaoshi oral liquid attenuates high-calorie diet-induced dyspepsia in immature rats via regulating the pancreatic secretion pathway and maintaining the homeostasis of intestinal microbiota
Researchers found that a traditional Chinese herbal medicine formula called Jianwei Xiaoshi oral liquid improved functional digestive problems in young rats fed a high-calorie diet by regulating eight key proteins involved in pancreatic digestion and restoring healthy gut bacteria balance. The findings suggest potential therapeutic benefits of this herbal remedy for diet-induced digestive disorders in children.
Inhibitory Effects of Jiuzao Polysaccharides on Alcoholic Fatty Liver Formation in Zebrafish Larvae and Their Regulatory Impact on Intestinal Microbiota
Researchers investigated the protective effects of Laowuzeng Jiuzao polysaccharides on ethanol-induced alcoholic fatty liver in zebrafish larvae, finding that the polysaccharides reduced hepatic damage and regulated intestinal microbiota composition, suggesting therapeutic potential for alcohol-related liver disease.
Erchen Decoction Alleviates High-Fat Diet + AOM/DSS-Induced CRC by Ameliorating Cholesterol-Bile Acid Metabolism Disorder through Regulating FXR and the Gut Microbiota
Researchers found that Erchen Decoction, a traditional Chinese medicine formula, alleviates colorectal cancer progression in a high-fat diet mouse model by correcting cholesterol-bile acid metabolism disorders through modulation of FXR signaling and gut microbiota composition.
A Single Strain of Lactobacillus (CGMCC 21661) Exhibits Stable Glucose- and Lipid-Lowering Effects by Regulating Gut Microbiota
Researchers identified a novel Lactobacillus strain (CGMCC 21661) that outperformed fecal microbiota transplantation and Bifidobacterium in lowering blood glucose and lipids in diabetic mice, demonstrating stable therapeutic effects through gut microbiota regulation.
Natural Compounds in the Modulation of the Intestinal Microbiota: Implications in Human Physiology and Pathology
This review examines how natural compounds including polyphenols, fatty acids, and fiber can modulate the gut microbiome and affect human health. While focused on nutrition and gut health rather than microplastics, the gut microbiome is increasingly recognized as a target of microplastic toxicity, making dietary protective factors relevant.
Dysbiosis of gut microbiota in C57BL/6-Lepem1hwl/Korl mice during microplastics-caused hepatic metabolism disruption
Researchers administered polypropylene microplastics orally to obese mice for 9 weeks and found disruption of hepatic lipid, glucose, and amino acid metabolism alongside structural changes in gut microbiota, with microplastic-treated mice showing decreased hepatic lipid accumulation and altered abundance of specific bacterial genera.
Effects of frying on microplastics load in fish and implications on health
Researchers investigated the effects of polyethylene microplastics on gut microbiota composition in mice fed a high-fat diet, finding that microplastic exposure altered microbial diversity and increased gut permeability. Co-exposure with a high-fat diet amplified metabolic disruption.
Mechanism of Mulberry Leaves and Black Sesame in Alleviating Slow Transit Constipation Revealed by Multi-Omics Analysis
Researchers examined how mulberry leaves and black sesame alleviate slow transit constipation in a mouse model, measuring gut motility, microbiota composition, and intestinal gene expression. Both dietary interventions increased beneficial bacteria, enhanced gut peristalsis, and upregulated genes associated with intestinal motility, supporting their traditional use for digestive health.
The Traditional Chinese Medicine in Treating Diabetic Nephropathy: A Bibliometric Analysis
This bibliometric analysis reviews research trends on Traditional Chinese Medicine for treating diabetic nephropathy. The study identifies key research hotspots including the clinical efficacy of herbal treatments and their pharmacological mechanisms, with improving oxidative stress and regulating gut microbiota highlighted as promising directions for future investigation.
Impact of Microplastic Exposure on Blood Glucose Levels and Gut Microbiota: Differential Effects under Normal or High-Fat Diet Conditions
Mice exposed to polystyrene microplastics showed changes in blood sugar levels and gut bacteria, with the effects being worse when combined with a high-fat diet. The microplastics disrupted the balance of beneficial gut bacteria and increased markers associated with type 2 diabetes. This study suggests that microplastic exposure could contribute to blood sugar problems in people, especially those who already eat an unhealthy diet.
Immune mechanism of gut microbiota and its metabolites in the occurrence and development of cardiovascular diseases
This review examines immune mechanisms linking gut microbiota and its metabolites to cardiovascular diseases, explaining how disruptions in the microbiota-immune balance contribute to conditions such as atherosclerosis, hypertension, and heart failure.
Oral Exposure to Epoxiconazole Disturbed the Gut Micro-Environment and Metabolic Profiling in Male Mice
Researchers found that oral exposure to the fungicide epoxiconazole disrupted gut microbiota composition and metabolic profiling in male mice, altering intestinal barrier function and mucus secretion with implications for gut health.
Oral exposure to polyethylene microplastics of adult male mice fed a normal or western-style diet: impact on gut and gut-liver axis homeostasis
Researchers orally exposed adult male mice to polyethylene microplastics under both normal and high-fat diets, assessing effects on the gastrointestinal tract. The study found that diet influences microplastic-induced gut changes, with greater effects observed in animals fed a western-style high-fat diet.
Long-term exposure to polystyrene microplastics promotes HFD-induced obesity in mice through exacerbating microbiota dysbiosis
Researchers found that long-term polystyrene microplastic exposure worsened high-fat-diet-induced obesity in mice by exacerbating gut microbiota dysbiosis, suggesting microplastic ingestion may amplify metabolic disease risk through disruption of the gut microbiome.
Molecular LandscapeRemodeling Unravels the Cross-Linksof Microplastics-Induced Lipidomic Fluctuations,Nutrient Disorders and Energy Disarrangements
Researchers examined polypropylene microplastic retention in mouse liver using lipidomics and transcriptomics, finding that chronic exposure disrupted lipid metabolism, cholesterol turnover, and antioxidant defense, with high-dose treatment causing regional liver fibrosis.
Long-Term Exposure to Polystyrene Microspheres and High-Fat Diet-Induced Obesity in Mice: Evaluating a Role for Microbiota Dysbiosis.
A long-term mouse study examined how chronic exposure to polystyrene microspheres interacts with a high-fat diet to affect obesity-related outcomes, finding that microplastics worsened metabolic disruption and fat accumulation compared to diet alone. The results raise concern that microplastic exposure may be an environmental factor contributing to the global obesity epidemic.
Epigallocatechin-3-gallate ameliorates polystyrene microplastics-induced anxiety-like behavior in mice by modulating gut microbe homeostasis
A mouse study found that exposure to polystyrene microplastics caused anxiety-like behavior by disrupting gut bacteria and triggering brain inflammation. A green tea compound called EGCG (epigallocatechin-3-gallate) reversed these effects by restoring healthy gut microbe balance and reducing inflammation in the brain. This suggests the gut-brain connection plays a key role in how microplastics affect mental health, and that certain dietary compounds might offer protection.
Microplastics and Metabolism: Physiological Responses in Mice Following Ingestion
Researchers found that mice orally exposed to microplastic microspheres showed changes in lipid metabolism and other metabolic pathways, with particles detected in tissues throughout the body. The effects were more pronounced when mice were exposed to mixed microplastic types compared to polystyrene alone, suggesting that real-world mixtures of microplastics may have broader physiological impacts.
Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice
Researchers fed mice two sizes of polystyrene microplastics for five weeks and observed significant disruption of gut bacteria and changes in liver fat metabolism. The microplastics decreased mucus production in the gut and shifted the balance of key bacterial populations at multiple taxonomic levels. The study suggests that microplastic ingestion can trigger gut microbiota imbalance in mammals, which may in turn affect metabolic health.
Supporting information.
Researchers found that nine weeks of oral polystyrene microplastic administration disrupted hepatic lipid, glucose, and amino acid metabolism in leptin-knockout obese mice while also altering fecal microbiota composition, suggesting that microplastic exposure compounds metabolic dysfunction in obesity.