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61,005 resultsShowing papers similar to Evaluation of the Anti-Inflammatory and Antioxidant Potential of Cymbopogon citratus Essential Oil in Zebrafish
ClearZebrafish models for the evaluation of essential oils (EOs): A comprehensive review
This comprehensive review examines how zebrafish models have been used to evaluate the biological effects and safety of essential oils derived from aromatic plants. Researchers summarize findings on toxicity screening as well as beneficial activities including antioxidant, anti-inflammatory, and neuromodulatory effects. The study concludes that zebrafish offer a valuable, cost-effective model for accelerating the identification and quality assessment of essential oils with potential health applications.
Unveiling the Effects of Fennel (Foeniculum vulgare) Seed Essential Oil as a Diet Supplement on the Biochemical Parameters and Reproductive Function in Female Common Carps (Cyprinus carpio)
Researchers investigated the effects of fennel seed essential oil on the health and reproductive function of common carp over 60 days. At lower doses, the oil improved growth rates and immune parameters, while the highest dose elevated stress-related enzyme levels. The study suggests that fennel oil at moderate doses could serve as a beneficial dietary supplement for farmed fish.
Protective Effects of Curcumin and/or Ginger Supplementation against Oreochromis niloticus Oxidative Stress Induced by Ultraviolet-A Radiation
Researchers found that dietary supplementation with curcumin and/or ginger significantly protected Nile tilapia from oxidative stress induced by ultraviolet-A radiation, improving antioxidant enzyme activity and reducing DNA fragmentation and lipid peroxidation. The findings suggest these natural compounds can serve as effective antioxidant feed additives in aquaculture.
The Interaction between Oxidative Stress Biomarkers and Gut Microbiota in the Antioxidant Effects of Extracts from Sonchus brachyotus DC. in Oxazolone-Induced Intestinal Oxidative Stress in Adult Zebrafish
Researchers found that extracts from Sonchus brachyotus DC. alleviated oxazolone-induced intestinal oxidative stress in zebrafish by modulating antioxidant enzyme activity and reshaping gut microbiota composition.
Chemical Composition, In Vitro Antitumor Effect, and Toxicity in Zebrafish of the Essential Oil from Conyza bonariensis (L.) Cronquist (Asteraceae)
Researchers analyzed the essential oil from the plant Conyza bonariensis and found it showed selective activity against melanoma cells in laboratory tests. The study used zebrafish as a model to assess toxicity and identified the compound lachnophyllum ester as the major component of the oil.
Dietary Curcumin Promotes Gilthead Seabream Larvae Digestive Capacity and Modulates Oxidative Status
Adding curcumin to the diet of gilthead seabream larvae improved their digestive capacity and antioxidant status. The research explores natural dietary supplements for improving fish health in aquaculture, which is relevant as farmed seafood is a source of microplastic exposure for humans.
Ameliorating potential of Cassia absus seed-powder against cadmium-induced alterations in Zebrafish and identification of flavonoids in different extracts of seed
Researchers investigated the protective effects of Cassia absus seed powder against cadmium-induced toxicity in zebrafish, finding it reduced oxidative stress and histological damage, while identifying flavonoid compounds in the seed extracts as likely active components.
Effect of dietary cinnamon supplementation on the growth in length, haematology, serum biochemistry, intestinal microbiota and enzymes and histomorphological changes of the intestine, liver and the kidney of Heteroclarias (Clarias gariepinus ♀ × Heterobra ♂)
Dietary cinnamon supplementation at 1-2% significantly improved growth, blood parameters, antioxidant enzyme activity, and intestinal health in juvenile catfish over a 56-day trial. The spice enhanced beneficial gut microbiota while reducing pathogenic bacteria, suggesting cinnamon as a natural feed additive for aquaculture.
Anti-pathogenicity of Acanthus ilicifolius leaf extracts against A. hydrophila infection in Labeo rohita fingerlings
Researchers evaluated leaf extracts from the mangrove plant Acanthus ilicifolius as a potential herbal alternative to antibiotics for managing bacterial infections in aquaculture fish. The methanol extract showed the highest antibacterial and antioxidant activity, and when used to treat Aeromonas hydrophila-infected fish fingerlings, it achieved a 94% survival rate compared to 0% in untreated controls.
Effects of dietary methanolic extract of hyssop, Hyssopus officinalis, on growth performance, hepatic antioxidant, humoral and intestinal immunity, and intestinal bacteria of rainbow trout, Oncorhynchus mykiss
Researchers found that dietary supplementation with hyssop (Hyssopus officinalis) methanolic extract in rainbow trout boosted immune markers including leukocyte counts and lysozyme activity, without significantly affecting growth performance, suggesting potential as a natural immune enhancer in aquaculture.
The protective efficacy of dual dietary rosemary plus cinnamon mix against lead nitrate-induced immune suppression, genotoxicity, and oxidant/antioxidant status in Nile tilapia fingerlings
Researchers tested whether a dietary mix of rosemary and cinnamon could protect Nile tilapia from the harmful effects of lead exposure. Fish exposed to lead showed reduced growth, suppressed immunity, increased oxidative stress, and DNA damage, but those fed the herbal supplement showed significant improvements across all measures. The study suggests that rosemary and cinnamon supplementation may help mitigate heavy metal toxicity in farmed fish.
Protective effects of exocarpium citri grandis extract and its flavonoid components against polystyrene microplastic-induced hepatointestinal injury
Scientists found that an extract from citrus fruit peels (called ECG) helped protect mice from liver and gut damage caused by tiny plastic particles. The citrus extract reduced harmful inflammation and oxidative stress while improving healthy gut bacteria balance. This research suggests that natural compounds from citrus peels might help protect our bodies from the health risks of microplastics that we encounter in our food and environment.
Citrus limon Essential Oil: Chemical Composition and Selected Biological Properties Focusing on the Antimicrobial (In Vitro, In Situ), Antibiofilm, Insecticidal Activity and Preservative Effect against Salmonella enterica Inoculated in Carrot
This study analyzed the chemical makeup and antimicrobial properties of lemon essential oil, finding it effective against various harmful bacteria and their protective biofilms. While not directly related to microplastics, natural antimicrobial compounds are being explored as alternatives to synthetic preservatives that can contribute to plastic-packaged food contamination.
Micro-algal astaxanthin ameliorates polystyrene microplastics-triggered necroptosis and inflammation by mediating mitochondrial Ca2+ homeostasis in carp’s head kidney lymphocytes (Cyprinus carpio L.)
Researchers investigated whether astaxanthin, a natural pigment from microalgae, could protect carp immune cells from damage caused by polystyrene microplastics. They found that astaxanthin reduced inflammation and cell death triggered by microplastics by helping maintain calcium balance within the cells' mitochondria. The study suggests that natural antioxidant compounds may help mitigate some of the harmful immune effects of microplastic exposure in fish.
Quercetin Prevents Bisphenol S Induced Behavioral Changes and Oxidative Stress iZebrafish by Modulating Brain Antioxidant Defense Mechanism
Researchers found that quercetin supplementation in zebrafish exposed to bisphenol S reduced oxidative stress markers and normalized abnormal behavioral responses in the brain, suggesting the natural antioxidant may counteract some neurotoxic effects of this common plastic additive.
Effects of Metamifop on Defense Systems in Monopterus albus
Researchers exposed the rice field fish Monopterus albus to the herbicide metamifop at four concentrations, finding dose-dependent increases in reactive oxygen species, oxidative damage markers, and apoptosis indicators. The results demonstrate that metamifop poses toxicity risks to non-target aquatic organisms in paddy field environments.
Application of transgenic zebrafish for investigating inflammatory responses to nanomaterials: Recommendations for new users
Researchers proposed using transgenic zebrafish expressing fluorescent proteins in immune cells as a screening tool for nanomaterial toxicity, demonstrating that inflammatory responses to nanomaterials can be visualized and quantified in non-protected life stages, offering a more ethically favorable alternative to rodent-based nanotoxicology studies.
Malathion-induced Biochemical and Molecular Changes in the Brain of Danio rerio as Biomarkers of Oxidative Stress Damage
Not relevant to microplastics — this study examines how the pesticide malathion causes oxidative stress and neurological damage in zebrafish brains, using antioxidant enzyme activity and gene expression as biomarkers.
The endocannabinoid system in zebrafish and its potential to study the effects of Cannabis in humans
Researchers reviewed how zebrafish — a small freshwater fish widely used in medical research — can serve as a model for studying how cannabis compounds interact with the body's endocannabinoid system, the network of receptors involved in pain, mood, and immune function. Zebrafish share many biological similarities with humans and allow faster, lower-cost studies than mammalian models, making them useful for testing potential cannabis-based therapies.
Natural Bioactive Phytocompounds to Reduce Toxicity in Common Carp Cyprinus carpio: A Challenge to Environmental Risk Assessment of Nanomaterials
Researchers investigated the toxic effects of copper oxide nanoparticles on common carp and found that Myristica fragrans seed extract provided protective benefits by reducing oxidative stress and mitigating nanoparticle-induced damage.
Inflammatory, Oxidative Stress, and Apoptosis Effects in Zebrafish Larvae after Rapid Exposure to a Commercial Glyphosate Formulation
Researchers examined the effects of acute exposure to a commercial glyphosate formulation on zebrafish larvae, observing inflammatory responses, oxidative stress, and cell death at environmentally relevant concentrations, suggesting potential risks to aquatic organisms.
Bioremediation of hemotoxic and oxidative stress induced by polyethylene microplastic in Clarias gariepinus using lycopene, citric acid, and chlorella
Researchers found that lycopene, citric acid, and chlorella provided protective bioremediation against polyethylene microplastic toxicity in African catfish, reducing hemotoxicity, oxidative stress, and tissue accumulation of MPs in the first study of phytobioremediation against MP toxicity in fish.
Evaluation of protective efficacy of quercetin on microplastic induced behavioural toxicity in zebrafish (Danio rerio)
Zebrafish were exposed to microplastics alone and in combination with quercetin at 75 ug/L for 21 days to evaluate whether quercetin could protect against microplastic-induced behavioral toxicity. Microplastic exposure caused behavioral abnormalities, and quercetin treatment modified these effects in a dose-dependent manner, suggesting antioxidant supplementation as a potential protective strategy.
The Impact of Microalgae and Their Bioactive Compounds on Liver Well-being in Rats Subjected to Synthetic Phenolic Antioxidants
This review examines how microalgae and their bioactive compounds — including polysaccharides, pigments, and polyphenols — protect liver health in animal models, summarizing evidence for anti-inflammatory and antioxidant mechanisms. The authors note that algal-derived compounds show hepatoprotective effects in rodent studies, though human clinical evidence remains limited.