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Evaluation of protective efficacy of quercetin on microplastic induced behavioural toxicity in zebrafish (Danio rerio)
Summary
Zebrafish were exposed to microplastics alone and in combination with quercetin at 75 ug/L for 21 days to evaluate whether quercetin could protect against microplastic-induced behavioral toxicity. Microplastic exposure caused behavioral abnormalities, and quercetin treatment modified these effects in a dose-dependent manner, suggesting antioxidant supplementation as a potential protective strategy.
The study was conducted to evaluate the protective effect of quercetin on microplastic induced behavioral abnormalities in zebrafish. Total 240 zebrafish were divided into six groups containing 40 fish in each. Group I served as control and other groups received microplastic and different dose of quercetin either alone or in combination. Research was conducted for the period of 21 days. Results of the study revealed behavioral abnormalities in microplastic alone treated group, quercetin (75 µg/L) alone treated group and in the group where microplastic was given with quercetin (75 µg/L).