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61,005 resultsShowing papers similar to Impact of prenatal micro/nanoplastics exposure on intrauterine development and growth: a systematic review
ClearHealth Implications of Microplastic Exposure in Pregnancy and Early Childhood: A Systematic Review
This systematic review summarizes existing research on how microplastic exposure during pregnancy and early childhood may affect health. The evidence shows that microplastics can reach the placenta and may cause oxidative stress and inflammation, raising concerns about potential effects on fetal development and infant health during these vulnerable life stages.
Microplastic Exposure During Pregnancy: A Systematic Review of Risks to Maternal and Fetal Health
This systematic review summarizes existing research on how microplastic exposure during pregnancy may affect mothers and developing babies. Studies suggest microplastics can cross the placental barrier, raising concerns about potential effects on fetal development, though more human research is needed to confirm specific risks.
Micro- and Nanoplastics and Fetal Health: Challenges in Assessment and Evidence from Epidemiological Studies
This review examines the emerging evidence that micro- and nanoplastics can reach the developing fetus during pregnancy, with animal studies showing potential effects on neurological development and placental blood flow. The study also highlights major challenges in accurately detecting and measuring these tiny particles in biological tissues from mothers and babies. The authors call for standardized methods and more human studies to better understand the risks of prenatal microplastic exposure.
Microplastics in the Perinatal Period: Emerging Evidence on Maternal Exposure, Placental Transfer, and Fetal Health Outcomes
This review summarizes emerging evidence that microplastics can cross the placenta and reach developing babies, having been detected in maternal blood, placental tissue, amniotic fluid, cord blood, and breast milk. The tiny plastic particles may damage the placenta, disrupt hormones, alter immune responses, and potentially affect fetal growth and brain development. While more research is needed, the findings raise serious concerns about microplastic exposure during pregnancy and its implications for infant health.
Impact of Microplastics on Pregnancy and Fetal Development: A Systematic Review
A systematic review of 12 studies confirmed the presence of microplastics ranging from 2.1 to 100 micrometers in human placentas and fetal tissue. Microplastic levels correlated with reduced birthweight, affected gestational age, diminished microbiome diversity, and impaired fetal growth and development, with lifestyle choices influencing placental microplastic burden.
Placental Exposure to Nanoplastics Threatening the Maternal and Fetal Health
This review examines how nanoplastics reaching the placenta threaten maternal and fetal health, summarizing evidence from animal and in vitro studies showing that placental nanoplastic accumulation disrupts nutrient transport, immune function, and fetal development.
The Impact of Maternal Nanoplastic and Microplastic Particle Exposure on Mammal’s Offspring
This review summarizes research on how a mother's exposure to nanoplastics and microplastics during pregnancy can affect her developing baby. Studies show that these tiny plastic particles can cross the placenta and reach the fetus, potentially harming brain development, the reproductive system, metabolism, and the immune system of offspring. The review calls for more research using realistic exposure levels to better understand the risks of prenatal microplastic exposure to human babies.
Microplastics: A threat to Fetoplacental unit and Reproductive systems
This review examines how micro- and nanoplastics may harm the placenta and reproductive system, particularly during pregnancy. The authors highlight that these tiny plastic particles have been found in placental tissue and may interfere with fetal development, though they note that much more research is needed to understand the full risks to mothers and babies.
Examining the hidden dangers: Understanding how microplastics affect pregnancy
This review examines how microplastics may affect pregnancy, covering how these tiny particles enter the body through food, water, and air, and can potentially cross the placenta to reach the developing fetus. Early research suggests that the timing of exposure during pregnancy may influence the level of risk to both mother and baby. While the field is still young, the findings highlight pregnancy as a particularly vulnerable period for microplastic exposure.
Breach of Security? Placental Uptake of Micro- and Nanoplastic Particles
This review examines emerging evidence for placental uptake of micro- and nanoplastic particles, exploring whether the placenta's barrier function can be breached by these contaminants during pregnancy. The review raises concerns about potential fetal exposure to plastic particles and the implications for developmental health.
Exposure to micro- and nanoplastics and human reproductive outcomes: a systematic review
This systematic review summarizes existing research on whether micro and nanoplastics affect human fertility and pregnancy outcomes. While the evidence is still emerging, the review found that these particles have been detected in placenta and fetal tissue, raising important questions about potential effects on reproductive health that warrant further study.
Assessing microplastics as a novel threat to maternal-fetal health: Placental barrier penetration and fetal developmental consequences
This review addressed how microplastics cross the placental barrier and affect fetal development, covering cellular responses in placental tissue, animal model findings, and limited human study data. The authors concluded that transplacental microplastic transfer is a plausible mechanism for intergenerational health effects.
A Systematic Review of the Placental Translocation of Micro- and Nanoplastics
Nine out of eleven studies confirmed that micro- and nanoplastics can cross the placental barrier, with translocation depending on particle size, charge, chemical modification, and protein corona formation. Animal and in vitro studies showed emerging evidence of placental and fetal toxicity from plastic particle exposure.
Impacts of micro- and nanoplastics on early-life health: a roadmap towards risk assessment
Researchers proposed a detailed risk assessment roadmap specifically for how micro- and nanoplastic exposure during pregnancy and early childhood could harm fetal and infant development, noting that these tiny particles have already been detected in human placentas. The framework identifies critical gaps in dosing data, detection methods, and placental transfer research needed before reliable safety conclusions can be drawn.
Maternal Exposure to Polystyrene Micro- and Nanoplastics Causes Fetal Growth Restriction in Mice
Researchers exposed pregnant mice to polystyrene micro and nanoplastics and found that exposure caused fetal growth restriction and placental abnormalities. The study observed that plastic particles accumulated in placental tissue and disrupted normal placental function. These findings raise concern that maternal exposure to plastic particles during pregnancy may interfere with fetal development.
Micro- and nanoplastic inhalation during pregnancy: Impacts on uteroplacental function and offspring health
This review examined evidence that inhaled micro- and nanoplastics during pregnancy accumulate in placental and fetal tissues, impair uteroplacental blood flow and immune function, and are associated with adverse developmental outcomes in offspring, identifying inhalation as a critical but understudied exposure route.
Microplastics: A threat for developing and repairing organs?
This review examines how micro- and nanoplastics may affect organ development and repair in humans and animals. Researchers found evidence that these particles and their chemical additives can disrupt critical developmental processes in multiple organs, including during fetal development via placental exposure. The study suggests that micro- and nanoplastics pose particular risks during early developmental windows and when the body is attempting to regenerate damaged tissue.
Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications
This review summarizes existing research on how nanoplastics (tiny plastic particles smaller than one micrometer) affect reproductive health in animals and potentially humans. Studies show that nanoplastics can accumulate in reproductive organs including the placenta, and evidence from animal studies links exposure to hormone disruption, reduced fertility, and developmental problems. The authors highlight a significant knowledge gap about nanoplastic effects on human reproduction, despite growing evidence that these particles reach our reproductive systems.
What Health Concerns Could Micro and Nanoplastics Pose for Infants? A Review
Microplastics and nanoplastics have been detected in human placentas, meconium, and infant faeces, meaning babies can be exposed before and immediately after birth. This review examines what these early-life exposures might mean for infant health and development, and discusses broader policy responses to reduce plastic overproduction as the most direct route to protecting future generations.
Placental Micro- and Nanoplastic Contamination: A Systematic Review of Eco-Exposome Pathways to Preterm Birth and Neonatal Outcomes
This systematic review examined evidence that micro- and nanoplastics have been found in human placentas and may be linked to preterm birth. The particles appear to cause inflammation, oxidative stress, and disruption of placental function through multiple molecular pathways, raising concerns about the impact of plastic pollution on pregnancy outcomes and newborn health.
Impact of microplastics and nanoplastics on human health: Mechanistic insights and exposure pathways
This review examines how microplastics and nanoplastics enter the human body through ingestion, inhalation, and skin contact, and deposit in tissues including the lungs, kidneys, and gastrointestinal tract. Evidence indicates these particles can cross embryonic layers and reach the placenta, and may cause inflammation, oxidative stress, metabolic disruptions, and immune system effects upon interaction with biological tissues.
Biological interactions between nanomaterials and placental development and function following oral exposure
Researchers reviewed animal studies on orally ingested nanomaterials (including nanoplastics) and found that while the placenta is generally an effective barrier preventing fetal transfer, nanomaterials accumulating in placental tissue can impair placental development and function, with potential downstream effects on fetal health.
Bridging the Gaps between Microplastics and Human Health
This review summarizes how microplastics and nanoplastics enter the human body through breathing, eating, drinking, skin contact, and even transfer from mother to fetus during pregnancy. Once inside, these particles can cross tissue barriers and potentially affect cellular processes important for fetal development. While the health effects are still being studied, the evidence so far points to real concerns about reproductive and developmental impacts from our daily plastic exposure.
Microplastics exposure: implications for human fertility, pregnancy and child health
This review examines growing evidence that microplastics accumulate in the human placenta and may affect pregnancy outcomes and child development. Given that exposure during pregnancy can program lifelong health in offspring, the presence of these tiny plastic particles in reproductive tissues raises important concerns about fertility, pregnancy complications, and children's health.