Papers

61,005 results
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Article Tier 2

Particulate contamination of human placenta: Plastic and non-plastic

Researchers examined human placentas and found both microplastic particles and non-plastic particulates embedded in the tissue, confirming that the womb is not a fully protected environment. This study highlights that unborn babies are exposed to a mixture of environmental contaminants before birth, raising questions about how these particles might affect fetal development.

2024 Environmental Advances 27 citations
Article Tier 2

Detection of Microplastic in Human Placenta and Meconium in a Clinical Setting

Researchers detected microplastic particles larger than 50 micrometers in human placenta and meconium (a baby's first stool) collected during cesarean deliveries. This is significant because it provides direct evidence that microplastics are present in the womb and are being passed to babies before and during birth. The study emphasizes the need for careful contamination controls in clinical studies and calls for further research on nano-sized plastics in human tissue.

2021 Pharmaceutics 438 citations
Article Tier 2

Microplastics in maternal blood, fetal appendages, and umbilical vein blood

Researchers detected 16 different types of microplastics in maternal blood, umbilical cord blood, and fetal tissues (placenta, amniotic fluid, fetal membrane, and umbilical cord) from 12 pregnant women who delivered by cesarean section. The most common plastics found were polyamide and polyurethane, and microplastic levels in amniotic fluid increased with maternal age and pre-pregnancy body weight, confirming that these particles can pass from mother to fetus.

2024 Ecotoxicology and Environmental Safety 36 citations
Article Tier 2

Plasticenta: First evidence of microplastics in human placenta

In a landmark study, researchers detected microplastics in human placental tissue for the first time, finding 12 plastic fragments in placentas from four out of six women with healthy pregnancies. The particles were identified as polypropylene and dyed plastics likely from packaging or cosmetics, raising concerns about potential effects on fetal development and pregnancy.

2020 Environment International 2970 citations
Systematic Review Tier 1

Impact of Microplastics on Pregnancy and Fetal Development: A Systematic Review

A systematic review of 12 studies confirmed the presence of microplastics ranging from 2.1 to 100 micrometers in human placentas and fetal tissue. Microplastic levels correlated with reduced birthweight, affected gestational age, diminished microbiome diversity, and impaired fetal growth and development, with lifestyle choices influencing placental microplastic burden.

2024 Cureus 21 citations
Article Tier 2

The Invisible Threat: Microplastics in Human Blood and Placenta

This review summarized current evidence on microplastic detection in human blood and placenta, discussing what is known about how these particles enter the bloodstream and reach fetal tissue. The authors highlight the potential implications for maternal and fetal health.

2024 Journal of Drug Delivery and Therapeutics 1 citations
Article Tier 2

Quantitation and identification of microplastics accumulation in human placental specimens using pyrolysis gas chromatography mass spectrometry

Researchers analyzed 62 human placenta samples and found microplastics in every single one, with concentrations ranging from 6.5 to 685 micrograms per gram of tissue. Polyethylene, the most common plastic in everyday products, made up 54% of the plastics found. This widespread presence of microplastics in placentas raises concerns about fetal exposure during pregnancy and potential effects on development.

2024 Toxicological Sciences 194 citations
Article Tier 2

Year 116 of the plastic age: a Pandora’s box as a time bomb for pregnancy? Review of clinical and fundamental data on prenatal exposure to plastics

This review examined evidence for micro- and nanoplastic presence in the human placenta and assessed implications for pregnancy outcomes, synthesizing in vitro, ex vivo, and epidemiological data. Multiple plastic types were detected in placental tissue from the basal plate to fetal membranes, and the authors raised concerns about placental dysfunction and fetal developmental risk.

2025 Journal of Hazardous Materials
Article Tier 2

Placental plastics in young women from general population correlate with reduced foetal growth in IUGR pregnancies

Researchers analyzed placenta samples from 43 women and found plastic particles present, then examined whether their presence correlated with birth outcomes. They found a significant association between higher concentrations of placental plastics and reduced fetal growth in pregnancies affected by intrauterine growth restriction. The study provides early evidence suggesting that plastic particle accumulation in the placenta may be linked to impaired fetal development.

2022 Environmental Pollution 156 citations
Article Tier 2

Microplastics exposure: implications for human fertility, pregnancy and child health

This review examines growing evidence that microplastics accumulate in the human placenta and may affect pregnancy outcomes and child development. Given that exposure during pregnancy can program lifelong health in offspring, the presence of these tiny plastic particles in reproductive tissues raises important concerns about fertility, pregnancy complications, and children's health.

2024 Frontiers in Endocrinology 115 citations
Article Tier 2

Raman-guided exploration of placental microplastic exposure: Unraveling the polymeric tapestry and assessing developmental implications

Scientists examined placentas from 50 women after delivery and found microplastics in 62% of them, with seven different plastic types identified including Teflon (PTFE), polystyrene, and ABS. While the particles did not appear to affect birth weight, length, or gestational age in this study, their widespread presence in placental tissue confirms that plastic pollution reaches developing babies before birth. More research is needed to understand potential long-term effects.

2024 Journal of Hazardous Materials 26 citations
Article Tier 2

The Association Between Microplastics and Microbiota in Placentas and Meconium: The First Evidence in Humans

Researchers analyzed placentas and meconium from 18 mother-infant pairs in Shanghai and found microplastics present in both, providing some of the first direct evidence of microplastic exposure during pregnancy and at birth. They also discovered correlations between microplastic presence and changes in microbial communities in these tissues. The study raises important questions about whether early-life microplastic exposure could influence infant health and development.

2022 Environmental Science & Technology 176 citations
Systematic Review Tier 1

Editorial: Maternal-fetal interface: new insight in placenta research, volume II

This editorial compiles research showing that microplastics have been detected in human placental tissue and induce cytotoxicity, oxidative stress, and metabolic disturbances in placental explants. The collection of studies underscores that environmental contaminants including microplastics represent a significant and urgent threat to placental function and fetal development.

2025 Frontiers in Endocrinology 1 citations
Article Tier 2

Impact of placental microplastics on birth anthropometrics: A cross-sectional study

Researchers studied placental microplastic content in 1,750 mother-infant pairs in China and examined associations with birth weight, length, and head circumference. Using advanced laser infrared imaging, they identified and quantified specific polymer types including PVC, polypropylene, PBS, and PET in placental tissue. The study provides large-scale evidence linking placental microplastic exposure to fetal growth measurements, contributing to the growing understanding of prenatal microplastic impacts.

2026 Ecotoxicology and Environmental Safety
Article Tier 2

Plastic and Life

Scientists developed new methods to detect tiny plastic particles in human placental tissue and found that these particles can get trapped in the placenta, with smaller pieces being retained more than larger ones. The research shows that plastic pollution has reached the most vulnerable stage of human life - unborn babies in the womb - though the particles don't seem to cross easily from mother to baby. This matters because we still don't know if these plastic particles could harm developing babies, making this an important area for future health research.

2026
Article Tier 2

Placental Exposure to Nanoplastics Threatening the Maternal and Fetal Health

This review examines how nanoplastics reaching the placenta threaten maternal and fetal health, summarizing evidence from animal and in vitro studies showing that placental nanoplastic accumulation disrupts nutrient transport, immune function, and fetal development.

2025 Health Dynamics
Article Tier 2

Microplastics: A threat to Fetoplacental unit and Reproductive systems

This review examines how micro- and nanoplastics may harm the placenta and reproductive system, particularly during pregnancy. The authors highlight that these tiny plastic particles have been found in placental tissue and may interfere with fetal development, though they note that much more research is needed to understand the full risks to mothers and babies.

2025 Toxicology Reports 15 citations
Systematic Review Tier 1

A Systematic Review of the Placental Translocation of Micro- and Nanoplastics

Nine out of eleven studies confirmed that micro- and nanoplastics can cross the placental barrier, with translocation depending on particle size, charge, chemical modification, and protein corona formation. Animal and in vitro studies showed emerging evidence of placental and fetal toxicity from plastic particle exposure.

2023 Current Environmental Health Reports 63 citations
Systematic Review Tier 1

Placental Micro- and Nanoplastic Contamination: A Systematic Review of Eco-Exposome Pathways to Preterm Birth and Neonatal Outcomes

This systematic review examined evidence that micro- and nanoplastics have been found in human placentas and may be linked to preterm birth. The particles appear to cause inflammation, oxidative stress, and disruption of placental function through multiple molecular pathways, raising concerns about the impact of plastic pollution on pregnancy outcomes and newborn health.

2025
Article Tier 2

Deeply in Plasticenta: Presence of Microplastics in the Intracellular Compartment of Human Placentas

Researchers analyzed human placenta samples and for the first time located microplastics within the intracellular compartment of placental tissue, not just on the surface. They found various polymer types including polyethylene and polypropylene embedded inside placental cells. The discovery that microplastics penetrate into the interior of human cells raises new questions about their potential biological effects during pregnancy.

2022 International Journal of Environmental Research and Public Health 165 citations
Article Tier 2

Placental microplastics contamination and its impact on thyroid function in newborns

Researchers analyzed placental tissue from over 1,200 mother-child pairs and found microplastics present in the samples, then examined whether these levels were associated with thyroid hormone profiles in the newborns. The study found associations between placental microplastic contamination and variations in newborn thyroid function, which is critical for early growth and development. These findings suggest that prenatal microplastic exposure warrants further investigation as a potential factor in infant health.

2025 Ecotoxicology and Environmental Safety 3 citations
Systematic Review Tier 1

Unveiling the presence of micro and nanoplastics in human biological matrices: A systematic review covering the latest five years from 2020 to 2025

This systematic review covering 2020-2025 confirmed the presence of micro- and nanoplastics in human blood, placenta, lungs, liver, kidneys, and other biological matrices. The findings demonstrate that plastic particles are accumulating in human tissues through ingestion, inhalation, and dermal contact, raising urgent questions about long-term health consequences.

2025 The Science of The Total Environment 1 citations
Article Tier 2

Human reproductive exposure to microplastics: A multi-technique analytical study of menstrual and amniotic fluids

Scientists found tiny plastic particles called microplastics in menstrual blood and amniotic fluid (the fluid that surrounds babies in the womb) for the first time. These plastic pieces came from common materials like water bottles and food packaging, showing that plastic pollution is reaching deep into our reproductive systems. While we don't yet know what health effects this might cause, the discovery raises important questions about how widespread plastic contamination could affect pregnancy and reproductive health.

2026 NanoImpact
Article Tier 2

Plasticizing Pregnancy: Microplastics Identified in Expectant Mothers’ Feces

Researchers detected microplastic polymers in the feces of pregnant women in Indonesia, providing evidence of microplastic exposure during pregnancy. The study identified several types of plastic particles present in the samples. The findings raise concerns about maternal microplastic exposure and highlight the need for further research into potential effects during pregnancy.

2024 Environmental Health Insights 17 citations