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61,005 resultsShowing papers similar to Systemic Accumulation and Distribution of Micro- and Nanoplastics in Human Tissues and Their Impact on Health: A Systematic Review
ClearMicroplastics in Human Tissues: Sources, Distribution, Toxicological Effects, and Health Implications
Researchers reviewed the growing body of evidence that microplastics accumulate in human tissues — including lung, blood, placenta, breast milk, and heart tissue — where they can trigger inflammation, oxidative stress, and cell death. The review highlights urgent knowledge gaps around how plastic particles move through the body and what their long-term health effects may be.
A systematic review of the impacts of exposure to micro- and nano-plastics on human tissue accumulation and health
This systematic review found growing evidence that micro- and nanoplastics accumulate in human tissues including lungs, gut, and blood, with lab studies showing potential disruption to immune, reproductive, endocrine, and nervous systems. The review identifies ingestion, inhalation, and dermal contact as the three main exposure routes and highlights that the smallest nanoplastic particles pose the greatest concern due to their ability to cross biological barriers.
The Plastic Within: Microplastics Invading Human Organs and Bodily Fluids Systems
This review documents the presence of microplastics in human organs and body fluids including the liver, blood, heart, placenta, breast milk, lungs, and reproductive tissues. The particles enter through ingestion, inhalation, and skin contact, and may also be introduced through invasive medical procedures. The widespread distribution of microplastics throughout the body raises concerns about their potential effects on organ function and long-term health.
Unveiling the presence of micro and nanoplastics in human biological matrices: A systematic review covering the latest five years from 2020 to 2025
This systematic review covering 2020-2025 confirmed the presence of micro- and nanoplastics in human blood, placenta, lungs, liver, kidneys, and other biological matrices. The findings demonstrate that plastic particles are accumulating in human tissues through ingestion, inhalation, and dermal contact, raising urgent questions about long-term health consequences.
Microplastics and Nanoplastics in human tissues: Systematic review of evidence, analytical protocols, and methodological challenges
This systematic review pulls together evidence on microplastics and nanoplastics found in human tissues like lungs, liver, and placenta. It confirms that tiny plastic particles are accumulating in our bodies, though detection methods still vary widely between studies, making it hard to compare results.
A critical review of micro- and nanoplastic permeation in the human body
This critical review examines how micro- and nanoplastics enter and move through the human body after exposure through food, beverages, and air. Researchers synthesized evidence showing these particles have been detected in multiple human tissues and organs, raising concerns about their potential long-term health effects from chronic environmental exposure.
Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.
Distribution and health impacts of micro- and nanoplastics (MNPs) in human organs: Accumulation, translocation, and toxicity – A systematic review of current evidence
This systematic review summarizes evidence on where micro- and nanoplastics accumulate in the human body. Researchers found these particles in stool, blood, lungs, placenta, and arterial plaques, with polyethylene and polystyrene being the most common types. The findings suggest microplastics can travel through the body and may contribute to inflammation and cardiovascular risk.
Micro and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review covers how micro- and nanoplastic particles enter the human body through ingestion, inhalation, infusion, and skin absorption, distribute to virtually all tissues and organs via the circulatory system, and cause health impacts including inflammatory responses, cellular damage, and endocrine disruption.
Systematic Literature Review: The Presence of Microplastics in the Body and their Impact on Human Health
This systematic review examined evidence on where microplastics accumulate in the human body and what health effects they may cause. Researchers found that microplastics have been detected in various human tissues and can enter the body through ingestion, inhalation, and skin contact. Evidence indicates that microplastics may trigger oxidative stress and inflammation, with potential effects on the digestive, respiratory, reproductive, endocrine, and nervous systems.
Microplastics in the human body: A comprehensive review of exposure, distribution, migration mechanisms, and toxicity
This comprehensive review pulls together research on how microplastics enter the human body through food, air, and skin contact, and where they accumulate in organs and tissues. The review discusses how particle size determines whether microplastics can cross biological barriers like the gut lining and blood-brain barrier. The authors conclude that microplastics pose significant health risks and call for more research into their long-term effects.
Microplastics in humans: Current evidence of presence and their role in organ toxicity
This comprehensive review examined how microplastics enter the human body through ingestion, inhalation, dermal absorption, and maternal-fetal transfer, summarizing documented evidence of MP presence and toxic effects across multiple organs.
Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans
This comprehensive review traces the journey of nano- and microplastics through the human body, covering how they enter through breathing, eating, drinking, and skin contact. Once inside, the smallest particles can cross the gut and lung barriers, enter the bloodstream, and accumulate in organs including the liver, kidneys, and placenta. The review highlights significant knowledge gaps about long-term health effects but notes that the evidence for internal accumulation in humans is growing.
Health Impacts of Micro- and Nanoplastics in Humans: Systematic Review of In Vivo Evidence
This meta-analysis reviews 25 studies that directly measured micro- and nanoplastics in living human tissues and fluids. The evidence confirms that plastic particles accumulate in multiple organ systems, including the heart, reproductive organs, and gut, and are associated with inflammation and functional problems. This is some of the strongest direct evidence that microplastics are present inside our bodies and may be affecting our health.
Effects of Microplastics on Human Physiology: Mechanisms of Toxicity and Health Risks
This systematic review summarizes research on how microplastics affect human body systems, covering studies from 2000 to 2025. The evidence shows that microplastics have been found in blood, placenta, and reproductive tissues, and can trigger inflammation, oxidative stress, and immune responses. While more research is needed, the findings suggest microplastics may contribute to chronic health conditions through multiple biological pathways.
[Human Accumulation and Toxic Effects of Microplastics：A Critical Review].
This review summarizes how microplastics enter the human body through food, drinking water, and air, and where they tend to accumulate in organs and tissues. Researchers found evidence that microplastics can trigger inflammatory responses and oxidative stress in the body. The study calls for more research into the long-term health effects of continuous microplastic exposure in humans.
Why Detecting Nanoplastics in Humans Matters: Exposure Routes, Biological Evidence, and Potential Health Implications
This review summarizes current evidence on nanoplastic detection in human biological samples, including blood, lung tissue, placenta, and brain samples, confirming that human exposure involves internal uptake rather than just environmental contact. The study discusses how ingestion and inhalation are the dominant exposure pathways, while experimental research suggests nanoplastics may induce oxidative stress, inflammation, and endocrine disruption, though direct causal links in humans remain limited.
Harmful Effects of Microplastics and Nanoplastics in Human Body Systems: A Systematic Review
A new review of 30 studies found that tiny plastic particles called microplastics are now widespread in human bodies, showing up in blood, lungs, and other organs. Higher levels of these plastic particles were linked to more severe disease in the heart, lungs, digestive system, and reproductive organs. This research suggests that the plastic pollution around us may be harming our health, though more studies are needed to prove these plastics directly cause disease.
Toxicokinetic Effects of Micro/Nano Plastics on Human Health
This review covers the toxicokinetics of micro- and nanoplastics in humans, examining how particles enter the body through ingestion, inhalation, and skin contact, distribute across organs via the circulatory system, and trigger cellular and biochemical responses at the tissue level.
The Invisible Intruder: a Review of Microplastics Accumulation in Human Tissues and Implications for Public Health, with Emphasis on Reproductive Health
This review synthesizes biomonitoring studies on microplastic and nanoplastic accumulation in human tissues, with particular emphasis on reproductive health effects. Researchers found these particles have been detected in blood, lungs, placentas, breast milk, testes, and brain tissue, raising questions about potential long-term implications for human health and reproduction.
Effects of Microplastics on Human Physiology: Mechanisms of Toxicity and Health Risks
This systematic review of 48 studies found that microplastics have been detected in human blood, placenta, and reproductive tissues, showing they can cross biological barriers. The most common harmful effects include oxidative stress, inflammation, hormonal disruption, and DNA damage, raising serious questions about long-term health consequences.
Tracing Microplastics in the Human Body: From Detection to Disease Mechanisms
This review traces the detection of microplastics across multiple human tissues — from nasal lavage and bronchoalveolar fluid to blood and lung tissue — and examines the disease mechanisms linking plastic particle accumulation to respiratory, cardiovascular, and other systemic health effects.
Microplastics in the Human Food Chain: Exposure and Health Implications
This review documents how microplastics have permeated the human food chain and are now detected in human tissues including lungs, liver, placenta, and breast milk, examining exposure routes through ingestion, inhalation, and dermal contact and the potential health consequences of this ubiquitous contamination.
Bioaccumulation of Microplastics: From Environmental Pollutants to Multisystemic Toxicity in Humans
This review examined how microplastics accumulate in the human body and the potential toxic effects across multiple organ systems. Researchers summarized evidence indicating that microplastics can enter the body through ingestion, inhalation, and skin contact, then distribute to organs including the gut, lungs, liver, and brain. The study highlights growing concerns about chronic low-level exposure and calls for more research into the long-term health implications of microplastic bioaccumulation.