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20 resultsShowing papers similar to Developmental Dynamics of the Gut Virome in Tibetan Pigs at High Altitude: A Metagenomic Perspective across Age Groups
ClearVirome of high-altitude canine digestive tract and genetic characterization of novel viruses potentially threatening human health
Researchers conducted a metagenomics analysis of the viral community in the digestive tracts of nearly 2,000 dogs from high-altitude regions in China. The study identified 203 novel viruses across 11 known families, including the first detection of hepatitis E virus in dogs, highlighting potential zoonotic risks that warrant further surveillance.
Comparative Analysis of Nasal Microbial Community between Tibetan Sheep with different Ages
Researchers compared nasal microbial communities in adult and young Tibetan sheep using amplicon sequencing, finding that young sheep had greater bacterial diversity at the genus level with 185 genera significantly more abundant, though overall alpha diversity indices were similar between age groups.
Comparative Analysis of Gut Microbiota Provides Insights into High-altitude Adaptation in Rana kukunoris on the Qinghai-Xizang Plateau
Researchers used 16S rRNA gene sequencing to characterize and compare the gut microbiota of the high-altitude frog Rana kukunoris on the Qinghai-Xizang Plateau with two low-altitude frog species, Rana amurensis and Rana dybowskii. The comparative analysis aimed to identify microbial community differences that may reflect adaptive strategies to extreme high-altitude conditions including low oxygen and harsh temperatures.
Comparative analysis of gut fungal composition and structure of the yaks under different feeding models
Researchers compared the gut fungal communities of wild yaks, house-fed domestic yaks, and grazing domestic yaks on the Tibetan plateau. They found that wild and grazing yaks had significantly more diverse gut fungal communities than house-fed yaks, with the feeding model strongly influencing which fungal species thrived. The study suggests that natural grazing supports a richer gut microbiome in yaks compared to indoor feeding, with potential implications for animal health and digestion.
Viral metagenomics reveals persistent as well as dietary acquired viruses in Antarctic fur seals
Researchers analyzed the viruses present in the blood and feces of Antarctic fur seals and identified multiple novel viruses — including crustacean viruses likely acquired through diet — providing a baseline picture of the viral communities in this remote species that may be increasingly exposed to new pathogens through climate change and human activity.
Macrogenomes reveal microbial-mediated microplastic degradation pathways in the porcine gut: a hope for solving the environmental challenges of microplastics
A metagenomic study of pig gut contents found a diverse community of microorganisms harboring genes capable of breaking down multiple types of microplastics. This raises the intriguing possibility that gut microbiota in food animals may partially degrade ingested microplastics, but it also raises questions about whether breakdown products or altered microbial communities pose risks that pass up the food chain to humans.
Bacterial Community Structure and Its Influencing Factors in Surface Sediments of the Nyang River in the Dry Season, China
Researchers analyzed bacterial community diversity in surface sediments of the Nyang River in Tibet using high-throughput sequencing, finding that climate warming and human activities along this plateau river have measurably shaped microbial composition and structure.
Potential risk of microplastics in plateau karst lakes: Insights from metagenomic analysis
Researchers surveyed microplastic pollution in remote alpine lakes on the edge of the Tibetan Plateau, finding concentrations of 20 to 59 particles per liter in water and up to 997 particles per kilogram in sediments. Using metagenomic analysis, they discovered that microplastic surfaces harbored distinct microbial communities carrying antibiotic resistance and virulence genes. The study suggests that even pristine high-altitude ecosystems are affected by microplastic contamination with potential ecological risks.
Metagenomic insights into isolable bacterial communities and antimicrobial resistance in airborne dust from pig farms
Researchers studied bacterial communities and antimicrobial resistance in airborne dust from pig farms in Thailand using metagenomic sequencing. The study found the highest bacterial concentrations inside pig houses, with Staphylococcus and Enterococcus being the most frequently isolated species, and identified that the same resistant bacteria appeared across dust, feed, and fecal samples on individual farms.
Viral diversity and potential environmental risk in microplastic at watershed scale: Evidence from metagenomic analysis of plastisphere
Metagenomic analysis of plastisphere communities on microplastics collected from five freshwater sites revealed diverse viral communities including phages and potential animal pathogens, with plastic-associated viromes differing from those in surrounding water. The study identifies microplastics as previously overlooked carriers of viral diversity and potential environmental health risks in aquatic ecosystems.
Comparative Analysis of the Gut Microbiota between Two Horse Species
Researchers compared the gut microbiota of native Mongolian horses and imported Dutch Warmblood horses using genetic sequencing. They found notable differences in bacterial community composition between the two breeds, suggesting that host genetics plays a role in shaping gut microbial populations. The study adds to the growing understanding of how the gut microbiome varies across closely related animal species.
Diversity and potential functional characteristics of phage communities colonizing microplastic biofilms
Researchers used metagenomics to characterize phage communities colonizing microplastic biofilms, discovering 240 distinct virus types across polypropylene, polyethylene, and PET plastics that differed from those on stone surfaces, suggesting microplastics host unique viral communities with potential ecological implications.
Viral Metagenomics as a Tool to Track Sources of Fecal Contamination: A One Health Approach
This review evaluates viral metagenomics as a tool for tracking sources of fecal contamination across water, food, soil, and air within a One Health framework. Researchers found that viral metagenomics can complement traditional culture and PCR-based methods by identifying a broader range of viral indicators with narrow host ranges. The study discusses both the promise and current limitations of this approach, including challenges in sample processing and bioinformatics analysis.
Identification and prevalence of fluke infection in yak and Tibetan sheep around Qinghai Lake, China
This Chinese study identified and assessed the prevalence of liver and rumen flukes in yak and sheep grazing around Qinghai Lake. While focused on veterinary parasitology rather than microplastics, the study contributes to understanding the health of livestock in a remote region where plastic contamination of grazing land is an emerging concern.
Study on the association between microplastic exposure and gut microbiota based on metagenomics: A pilot study on 66 young college students in China
In a pilot study of 66 young college students in China, researchers analyzed stool samples to examine the relationship between microplastic exposure and gut microbiota composition. Participants with higher microplastic concentrations in their stools showed increased abundance of potentially harmful intestinal bacteria, with polystyrene microplastics having the most pronounced effect on gut microbial community structure.
Different living environments drive deterministic microbial community assemblages in the gut of Alpine musk deer (Moschus chrysogaster)
Researchers found that captive and wild Alpine musk deer harbor significantly different gut microbial communities, with living environment being a deterministic factor in shaping microbial assembly and diversity in this endangered ruminant.
Multidrug-resistant Escherichia coli causing diarrhea in yak calves on the Qinghai-Tibet Plateau: phenotypic characterization, whole-genome sequencing, and pathogenicity analysis
Scientists found dangerous, drug-resistant E. coli bacteria in sick yak calves in Tibet that doesn't respond to most common antibiotics. These "superbug" strains could potentially spread to humans through the food chain or environment, making infections much harder to treat. This highlights the growing global threat of antibiotic-resistant bacteria, especially in areas where antibiotics are used heavily in livestock.
Gut Microbiome and Small RNA Integrative-Omic Perspective of Meconium and Milk-FED Infant Stool Samples
Characterization of bacteriome, virome, and smallRNome in infant meconium and stool samples found that the gut environment changes rapidly after birth with the bacteriome, virome, and small RNA profiles all differing between meconium and milk-fed infant stool, suggesting transkingdom interactions shape early gut colonization.
Rare Bacteria Can Be Used as Ecological Indicators of Grassland Degradation
Researchers used full-length 16S rRNA sequencing to study bacterial communities across degraded grasslands on the Qinghai-Tibet Plateau, finding that rare bacterial taxa were more sensitive to grassland degradation and soil nutrient changes than abundant taxa, and that rare bacteria may serve as reliable ecological indicators of grassland health.
Integrated Analysis of the Transcriptome and Microbial Diversity in the Intestine of Miniature Pig Obesity Model
Researchers fed miniature pigs a high-fat, high-carbohydrate diet for 26 weeks and compared their gut health to pigs on a normal diet. The obesity-prone pigs showed increased inflammation, disrupted blood sugar metabolism, and significant declines in beneficial gut bacteria. The study reveals strong connections between diet-induced gut microbial changes and immune-related gene expression in the intestines.