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61,005 resultsShowing papers similar to Microplastics and Nanoplastics in Atheromas
ClearStandardizing methodologies to study microplastics and nanoplastics in cardiovascular diseases
Researchers highlighted that microplastics and nanoplastics are emerging as new risk factors for cardiovascular health, with evidence indicating they can impair blood vessel cell functions and worsen artery-clogging processes. However, the widely varying concentrations of these particles found in heart and vascular tissues point to a lack of standardized research methods. The study calls for unified approaches to better understand how plastic particles affect the cardiovascular system.
Micro- and nanoplastics are elevated in femoral atherosclerotic plaques compared with undiseased arteries
Researchers found significantly higher concentrations of microplastics and nanoplastics in diseased arterial plaques from human patients with limb-threatening vascular disease compared to healthy arteries, adding to growing evidence that these particles accumulate in cardiovascular tissue and may play a role in artery disease.
Microplastics and Nanoplastics in Atheromas and Cardiovascular Events
This landmark clinical study found that patients with micro- and nanoplastics detected in their carotid artery plaque had a significantly higher risk of heart attack, stroke, or death over a 34-month follow-up period compared to those without detectable plastics. This is one of the first studies to directly link microplastic presence in human blood vessels to worse cardiovascular outcomes. The findings suggest that plastic accumulation in arteries may be an important and previously unrecognized risk factor for heart disease.
Analytical techniques for detecting micro- and nanoplastics in blood and vascular tissues: Strengths and limitations
Researchers reviewed analytical techniques for detecting micro- and nanoplastics in blood and vascular tissues, assessing each method's strengths and limitations. The study highlights that human-derived samples pose unique challenges due to limited volumes, high lipid and protein content, and contamination risks, emphasizing the need for standardized protocols to produce reliable data for cardiovascular health research.
Tissue-specific distribution of microplastics in human blood and carotid plaques: A paired sample analysis
In a study of 20 patients undergoing surgery for clogged neck arteries, researchers found microplastics in both blood and artery plaque samples from every patient. The plaques contained nearly six times more microplastics than blood, suggesting that plastics accumulate in damaged blood vessels. Some types of microplastics were linked to changes in cholesterol levels, raising questions about whether plastic particles could worsen heart disease.
Evidence, Mechanisms, and Clinical Implications of Microplastics and Nanoplastics As Emerging Cardiovascular Risk Factors: A Narrative Review
This review examines growing evidence that micro- and nanoplastics may contribute to cardiovascular health risks, with researchers having found these particles in human artery plaques and blood clots. Evidence indicates that the particles can enter the bloodstream, trigger inflammation, damage blood vessel walls, and potentially increase the risk of heart attacks and strokes. While the evidence is not yet conclusive, the study highlights an emerging area of concern that warrants further investigation into how everyday plastic exposure may affect heart and blood vessel health.
Weekly Journal Scan: Plastic particles in carotid plaques—inactive debris or predictors of cardiovascular events?
This journal scan summarizes a prospective multicenter study that detected microplastics and nanoplastics in excised carotid artery plaques and found that higher plaque burden of plastic particles was associated with increased risk of cardiovascular events. The findings raise the possibility that microplastics in arterial tissue are not inert but biologically active.
Micro and Nano-plastic particles: What are they and do they effect cardiovascular health?
This review examines the cardiovascular health effects of micro- and nanoplastics, summarizing evidence that these particles have been detected in human tissues including arterial plaques and may promote endothelial dysfunction and inflammation. The authors call for further clinical and epidemiological research into cardiac risk.
Microplastics release from coronary catheters: Insights from catheter analysis
This study examined whether cardiac catheters used in heart procedures release microplastic particles, and found that all 21 catheter samples tested shed microplastics of varying sizes and types. The findings raise important questions about patient safety, since these tiny plastic fragments could enter the bloodstream during routine cardiovascular procedures.
Kontaminasi dan Akumulasi Mikro-nanoplastik Dapat Menjadi Faktor Risiko Terbaru Penyakit Kardiovaskular
This review (in Indonesian) discusses how unmanaged plastic waste degrades into micro- and nanoplastics that contaminate air, water, soil, and living organisms including humans, and presents these particles as a newly recognized risk factor for cardiovascular disease.
Communicating confidence in the reliability of micro- and nanoplastic identification in human health studies
Researchers propose a framework for improving the reliability of micro- and nanoplastic identification in human health studies by integrating multiple analytical techniques. The study emphasizes the need for transparent reporting of methodological limitations and introduces confidence levels for particle identification, addressing the major challenge of contamination risk and the diverse properties of plastic particles in biological samples.
Multimodal detection and analysis of microplastics in human thrombi from multiple anatomically distinct sites
This study used multiple detection methods to find and analyze microplastics in blood clots (thrombi) collected from different locations in the human body. The detection of microplastics within blood clots from various anatomical sites suggests that plastic particles may play a role in clot formation. This research adds to mounting evidence linking microplastic presence in the cardiovascular system to potential heart and stroke risks.
Micro-Nano Plastic in the Aquatic Environment: Methodological Problems and Challenges
This critical review examines methodological inconsistencies in microplastic research, arguing that many studies conflate correlation with causation and that contamination controls and size detection limits are often inadequate. The authors call for more rigorous experimental design before concluding that microplastics are definitively harmful vectors for co-occurring contaminants.
Microplastics in cardiopulmonary bypass: quantification and characterization of particles across systems
Researchers measured microplastic contamination generated by cardiopulmonary bypass machines used during heart surgery and found significant levels of plastic particles across the systems tested. The study characterized the types and quantities of microplastics produced during machine operation. The findings raise questions about patient exposure to microplastics during cardiac procedures and highlight the need for further research into whether these particles have clinical significance.
Impact of microplastics and nanoplastics on cardiovascular health
This review examines the emerging evidence on how microplastics and nanoplastics may affect cardiovascular health. The study discusses clinical evidence suggesting that these particles can accumulate in the cardiovascular system and highlights possible molecular mechanisms including inflammation and oxidative stress, while noting that current evidence linking microplastics to cardiovascular disease remains largely correlative.
A critical viewpoint on current issues, limitations, and future research needs on micro- and nanoplastic studies: From the detection to the toxicological assessment.
This critical review examines the current methods for detecting and characterizing micro- and nanoplastics in various environmental samples, as well as reported toxic effects from in vivo and in vitro studies. The authors found that while substantial effort has been made to understand microplastic behavior, the scientific community is still far from a complete understanding of how these particles behave in biological systems. The review calls for improved standardized protocols and more studies focused on uptake kinetics, accumulation, and biodistribution.
Microplastics and nanoplastics: Exposure and toxicological effects require important analysis considerations
This review highlights that while microplastics and nanoplastics have been found in human tissues and linked to several diseases, the actual toxic effects are still unclear because researchers use very different methods to study them. The authors call for standardized testing approaches so that results can be compared reliably, which is critical for determining what levels of exposure actually pose a risk to human health.
P69 | Microplastics and Atherosclerosis: Evidence of Microplastics in Carotid Atherosclerotic Plaques
This conference abstract reports the detection of multiple types of microplastics in human coronary, carotid, and aortic arteries, finding higher MP concentrations in arteries with atherosclerotic plaques than in plaque-free aortic tissue, suggesting a link between microplastic accumulation and arterial disease.
Morphological and chemical characterization of nanoplastics in human tissue
Researchers developed methods to visualize and chemically characterize nanoplastics that have accumulated in human tissue samples. They were able to identify plastic particles smaller than one micrometer within tissue using advanced microscopy and spectroscopy techniques. The study provides some of the first direct evidence of nanoscale plastic accumulation in the human body, which is essential for designing future health effects research.
Microplastic in perfusion: the hidden risk and how to address it
This commentary addresses the emerging concern that cardiopulmonary bypass circuits and other extracorporeal circulation systems release significant levels of micro- and nanoplastics into patients during medical procedures. The authors note that the same properties making plastics ideal for medical tubing also make their degradation products potentially harmful. The study calls for further research into the clinical implications of plastic particle exposure during these increasingly common medical interventions.
Plastic in Arteries Tied With Higher Risk of Cardiovascular Problems
This report highlights research linking the presence of microplastics and nanoplastics in human arteries to a higher risk of cardiovascular problems. Evidence indicates that these tiny plastic particles have been found in common products like food containers, cosmetics, and drinking water, raising questions about their long-term effects on heart health.
Microplastics and Cardiovascular Disease: Should Clinicians Be Paying Attention?
This clinical review summarizes evidence for microplastics as a cardiovascular risk factor, noting that they have been detected in human cardiovascular tissues and that in vitro and animal studies link them to oxidative stress, endothelial dysfunction, and platelet disruption, while cautioning that human evidence remains associative.
Challenges and Advances in Analytical Techniques to Detect Micro- and Nanoplastics
This research review summarizes the current methods scientists use to detect and study microplastics and nanoplastics - tiny plastic particles that can get into our environment, food, and bodies. The authors explain that identifying these extremely small plastic pieces is very challenging and requires advanced laboratory techniques to understand what types of plastics they are and how much is present. Better detection methods are important because we need to understand how much plastic pollution we're exposed to and its potential effects on human health.
Response to the editor regarding “Identification and characterization of microplastics in human nasal samples”
This is a response to the editor addressing concerns raised about a previously published paper on identification and characterization of microplastics, clarifying methodological choices and data interpretation. The response defends the original paper's conclusions against technical criticisms.